SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bwy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 6bwy DU-EDITING ENZYME
APOBEC-3G FUSION
PROTECTION OF
TELOMERES PROTEIN 1,
DNA DC->
(Homo
sapiens;
Schizosaccharomy
ces
pombe) 		4 / 7 LEU A  65
PHE A  47
GLY A  67
ILE A 118
 None
 1.01A 2bdmA-6bwyA:
undetectable		 2bdmA-6bwyA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 6bwy PROTECTION OF
TELOMERES PROTEIN 1,
DNA DC->
DU-EDITING ENZYME
APOBEC-3G FUSION
(Schizosaccharomy
ces
pombe;
Homo
sapiens) 		4 / 6 ALA A 182
PHE A  66
ILE A  42
GLU A 178
 None
 0.95A 2cizA-6bwyA:
undetectable		 2cizA-6bwyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 6bwy DU-EDITING ENZYME
APOBEC-3G FUSION
PROTECTION OF
TELOMERES PROTEIN 1,
DNA DC->
(Homo
sapiens;
Schizosaccharomy
ces
pombe) 		5 / 12 ALA A 296
THR A 327
ALA A 321
ILE A 335
LEU A 220
 None
 1.20A 2nyrA-6bwyA:
undetectable		 2nyrA-6bwyA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME
KP18CYS PEPTIDE)		 6bwy PROTECTION OF
TELOMERES PROTEIN 1,
DNA DC->
DU-EDITING ENZYME
APOBEC-3G FUSION
(Schizosaccharomy
ces
pombe;
Homo
sapiens) 		5 / 12 TYR A  40
GLN A  48
SER A  52
ARG A  51
LEU A 185
 None
 1.37A 4k38A-6bwyA:
undetectable
4k38D-6bwyA:
undetectable		 4k38A-6bwyA:
undetectable
4k38D-6bwyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 6bwy PROTECTION OF
TELOMERES PROTEIN 1,
DNA DC->
DU-EDITING ENZYME
APOBEC-3G FUSION
(Schizosaccharomy
ces
pombe;
Homo
sapiens) 		5 / 12 TYR A  40
GLN A  48
SER A  52
ARG A  51
LEU A 185
 None
 1.41A 4k39A-6bwyA:
undetectable		 4k39A-6bwyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)		 6bwy DU-EDITING ENZYME
APOBEC-3G FUSION
PROTECTION OF
TELOMERES PROTEIN 1,
DNA DC->
(Homo
sapiens;
Schizosaccharomy
ces
pombe) 		5 / 10 LEU A 260
PRO A 287
ALA A 333
GLU A 294
LEU A 220
 None
 1.48A 4la0A-6bwyA:
undetectable		 4la0A-6bwyA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 6bwy DU-EDITING ENZYME
APOBEC-3G FUSION
PROTECTION OF
TELOMERES PROTEIN 1,
DNA DC->
(Homo
sapiens;
Schizosaccharomy
ces
pombe) 		4 / 5 ARG A  51
THR A  95
ASP A  93
TYR A  40
 None
 1.47A 4qwpB-6bwyA:
undetectable		 4qwpB-6bwyA:
17.12