SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bxe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 6bxe VARIABLE LYMPHOCYTE
RECEPTOR DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 12 LEU A 102
LEU A  78
LEU A  54
LEU A  88
LEU A  85
 None
 0.94A 1sqnB-6bxeA:
undetectable		 1sqnB-6bxeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 6bxe VARIABLE LYMPHOCYTE
RECEPTOR DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 5 GLY A  37
PRO A  44
VAL A  43
ILE A  61
 None
 0.78A 2aoiA-6bxeA:
undetectable		 2aoiA-6bxeA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 6bxe VARIABLE LYMPHOCYTE
RECEPTOR DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 10 LEU A  54
ILE A  47
PRO A  23
SER A  42
GLY A  45
 None
 1.32A 3ijxB-6bxeA:
undetectable
3ijxD-6bxeA:
undetectable		 3ijxB-6bxeA:
14.40
3ijxD-6bxeA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 6bxe VARIABLE LYMPHOCYTE
RECEPTOR DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 10 ILE A  47
PRO A  23
SER A  42
GLY A  45
LEU A  54
 None
 1.32A 3ik6B-6bxeA:
undetectable
3ik6E-6bxeA:
undetectable		 3ik6B-6bxeA:
14.40
3ik6E-6bxeA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 6bxe VARIABLE LYMPHOCYTE
RECEPTOR DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 10 LEU A  54
ILE A  47
PRO A  23
SER A  42
GLY A  45
 None
 1.34A 3ik6B-6bxeA:
undetectable
3ik6E-6bxeA:
undetectable		 3ik6B-6bxeA:
14.40
3ik6E-6bxeA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 6bxe VARIABLE LYMPHOCYTE
RECEPTOR DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 10 LEU A  54
ILE A  47
PRO A  23
SER A  42
GLY A  45
 None
 1.35A 3iluB-6bxeA:
undetectable
3iluE-6bxeA:
undetectable		 3iluB-6bxeA:
14.40
3iluE-6bxeA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 6bxe VARIABLE LYMPHOCYTE
RECEPTOR DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 11 ILE A  47
PRO A  23
SER A  42
GLY A  45
LEU A  54
 None
 1.34A 3iluB-6bxeA:
undetectable
3iluE-6bxeA:
undetectable		 3iluB-6bxeA:
14.40
3iluE-6bxeA:
14.40