SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6byf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 6byf TYROSINE-PROTEIN
PHOSPHATASE SIW14
(Saccharomyces
cerevisiae) 		3 / 3 ASN A 121
ARG A 131
ASP A 255
 None
 0.95A 2qe6A-6byfA:
undetectable		 2qe6A-6byfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 6byf TYROSINE-PROTEIN
PHOSPHATASE SIW14
(Saccharomyces
cerevisiae) 		3 / 3 ASN A 121
ARG A 131
ASP A 255
 None
 0.93A 2qe6B-6byfA:
undetectable		 2qe6B-6byfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 6byf TYROSINE-PROTEIN
PHOSPHATASE SIW14
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 155
ILE A 156
ALA A 198
VAL A 202
PHE A 134
 None
 1.41A 2qo4A-6byfA:
undetectable		 2qo4A-6byfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 6byf TYROSINE-PROTEIN
PHOSPHATASE SIW14
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 210
PHE A 142
PHE A 122
TYR A 130
 None
 1.27A 3elzB-6byfA:
undetectable		 3elzB-6byfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJR_A_0LAA404_1
(DNA POLYMERASE III
SUBUNIT BETA)		 6byf TYROSINE-PROTEIN
PHOSPHATASE SIW14
(Saccharomyces
cerevisiae) 		5 / 9 TYR A 243
THR A 221
GLY A 217
LEU A 155
VAL A 154
 None
None
CIT  A 301 (-4.0A)
None
None
 1.44A 4mjrA-6byfA:
undetectable		 4mjrA-6byfA:
12.67