SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6byk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 6byk 14-3-3 PROTEIN
BETA/ALPHA
(Homo
sapiens) 		3 / 3 ARG A  58
ILE A  88
TRP A  61
 None
 1.10A 1nodB-6bykA:
undetectable		 1nodB-6bykA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 6byk 14-3-3 PROTEIN
BETA/ALPHA
(Homo
sapiens) 		3 / 3 ARG A  58
ILE A  88
TRP A  61
 None
 1.13A 1qomA-6bykA:
undetectable		 1qomA-6bykA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 6byk 14-3-3 PROTEIN
BETA/ALPHA
(Homo
sapiens) 		3 / 3 ARG A  58
ILE A  88
TRP A  61
 None
 1.06A 2nodB-6bykA:
undetectable		 2nodB-6bykA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 6byk 14-3-3 PROTEIN
BETA/ALPHA
(Homo
sapiens) 		4 / 5 SER A 132
GLY A 125
GLU A 133
CYH A  96
 None
 1.22A 3aiaA-6bykA:
undetectable
3aiaB-6bykA:
undetectable		 3aiaA-6bykA:
undetectable
3aiaB-6bykA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6byk 14-3-3 PROTEIN
BETA/ALPHA
(Homo
sapiens) 		3 / 3 ARG A  58
ILE A  88
TRP A  61
 None
 1.09A 3e7iB-6bykA:
undetectable		 3e7iB-6bykA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6byk 14-3-3 PROTEIN
BETA/ALPHA
(Homo
sapiens) 		3 / 3 ARG A  58
ILE A  88
TRP A  61
 None
 0.99A 3nw2A-6bykA:
undetectable		 3nw2A-6bykA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6byk 14-3-3 PROTEIN
BETA/ALPHA
(Homo
sapiens) 		3 / 3 ARG A  58
ILE A  88
TRP A  61
 None
 1.00A 3nw2B-6bykA:
undetectable		 3nw2B-6bykA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 6byk 14-3-3 PROTEIN
BETA/ALPHA
(Homo
sapiens) 		5 / 11 ARG A  58
LEU A  92
LEU A 100
GLY A 125
ASP A 126
 None
 1.32A 3sfuC-6bykA:
undetectable		 3sfuC-6bykA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 6byk 14-3-3 PROTEIN
BETA/ALPHA
(Homo
sapiens) 		3 / 3 GLU A 210
LYS A 214
ASN A 209
 None
 0.93A 4y1dA-6bykA:
undetectable
4y1dD-6bykA:
undetectable		 4y1dA-6bykA:
undetectable
4y1dD-6bykA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6byk 14-3-3 PROTEIN
BETA/ALPHA
(Homo
sapiens) 		4 / 5 PHE A 198
THR A 217
MET A 220
ARG A 224
 None
 1.47A 5m35A-6bykA:
33.9		 5m35A-6bykA:
undetectable