SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6byw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		3 / 3 VAL B 245
VAL B 178
TRP B 176
 None
 0.94A 1av2A-6bywB:
undetectable
1av2B-6bywB:
undetectable		 1av2A-6bywB:
undetectable
1av2B-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		3 / 3 GLU B 446
ALA B 441
SER B 438
 None
None
SO4  B 903 (-4.1A)
 0.64A 1errB-6bywB:
undetectable		 1errB-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 8 SER B 731
ALA B 733
PHE B 741
ILE B 732
 None
 1.03A 1gm7A-6bywB:
undetectable
1gm7B-6bywB:
undetectable		 1gm7A-6bywB:
undetectable
1gm7B-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		3 / 3 ASP B 666
LYS B 184
ARG B 224
 None
 0.89A 1ra8A-6bywB:
undetectable		 1ra8A-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		3 / 3 TRP B 755
VAL B 703
PRO B 702
 None
 0.87A 1rg1A-6bywB:
undetectable		 1rg1A-6bywB:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		3 / 3 TRP B 755
VAL B 703
PRO B 702
 None
 0.88A 1rh0A-6bywB:
undetectable		 1rh0A-6bywB:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 6 ILE B 507
GLY B 506
ALA B 216
HIS B 583
 None
 0.93A 1wmqA-6bywB:
undetectable		 1wmqA-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 6 ILE B 507
GLY B 506
ALA B 216
HIS B 583
 None
 0.93A 1wmqB-6bywB:
undetectable		 1wmqB-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 6 ILE B 507
GLY B 506
ALA B 216
HIS B 583
 None
 0.92A 1wpuA-6bywB:
undetectable		 1wpuA-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 6 ILE B 507
GLY B 506
ALA B 216
HIS B 583
 None
 0.93A 1wpuB-6bywB:
undetectable		 1wpuB-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 6 ILE B 507
GLY B 506
ALA B 216
HIS B 583
 None
 0.97A 1wrqA-6bywB:
undetectable		 1wrqA-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 6 ILE B 507
GLY B 506
ALA B 216
HIS B 583
 None
 0.98A 1wrqB-6bywB:
undetectable		 1wrqB-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 7 SER B 308
SER B 310
SER B 311
ASN B 321
 None
 0.90A 2cmlA-6bywB:
undetectable		 2cmlA-6bywB:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 8 SER B 308
SER B 310
SER B 311
ASN B 321
 None
 0.80A 2cmlB-6bywB:
undetectable		 2cmlB-6bywB:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 8 SER B 308
SER B 310
SER B 311
ASN B 321
 None
 0.94A 2cmlC-6bywB:
undetectable		 2cmlC-6bywB:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 8 SER B 308
SER B 310
SER B 311
ASN B 321
 None
 0.91A 2cmlD-6bywB:
undetectable		 2cmlD-6bywB:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		5 / 12 LEU B 194
ILE B 597
ASN B 645
ALA B 642
ASP B 195
 None
 1.24A 2ejtA-6bywB:
undetectable		 2ejtA-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 7 LEU B 628
ASN B 629
LEU B 625
TYR B 634
 None
 1.26A 2w8yA-6bywB:
undetectable		 2w8yA-6bywB:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_1
(NEURAMINIDASE A)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		5 / 12 ARG B 404
ILE B 365
ASP B 360
TYR B  45
TYR B 807
 None
None
MG  B 901 (-2.8A)
None
None
 1.25A 2ya7A-6bywB:
undetectable		 2ya7A-6bywB:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_1
(NEURAMINIDASE A)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		5 / 12 ARG B 404
ILE B 365
ASP B 360
TYR B  45
TYR B 807
 None
None
MG  B 901 (-2.8A)
None
None
 1.26A 2ya7C-6bywB:
undetectable		 2ya7C-6bywB:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_1
(NEURAMINIDASE A)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		5 / 12 ARG B 404
ILE B 365
ASP B 360
TYR B  45
TYR B 807
 None
None
MG  B 901 (-2.8A)
None
None
 1.25A 2ya7D-6bywB:
undetectable		 2ya7D-6bywB:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 5 ALA B 362
GLN B 364
ILE B 365
ARG B 404
 MG  B 901 (-4.0A)
None
None
None
 1.48A 2z0aA-6bywB:
undetectable		 2z0aA-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		3 / 3 MET B 671
MET B 219
PHE B 582
 None
 1.12A 3gn8A-6bywB:
undetectable		 3gn8A-6bywB:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		5 / 11 LEU B  12
GLN B 623
TRP B 353
GLY B 329
GLY B 665
 None
 1.17A 3gy3A-6bywB:
undetectable		 3gy3A-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		3 / 3 ASN B 419
ASN B 426
GLU B 549
 None
 0.90A 3kpdC-6bywB:
undetectable		 3kpdC-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		3 / 3 ASN B 419
ASN B 426
GLU B 549
 None
 0.94A 3kpdB-6bywB:
undetectable		 3kpdB-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		3 / 3 TYR B 400
TYR B  39
GLU B 366
 None
 0.94A 3pfgA-6bywB:
undetectable		 3pfgA-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		5 / 12 VAL B 331
ALA B 352
ALA B 566
LEU B 295
TYR B 154
 None
 1.03A 3qxyA-6bywB:
undetectable		 3qxyA-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		5 / 11 VAL B 331
ALA B 352
ALA B 566
LEU B 295
TYR B 154
 None
 1.07A 3rc0A-6bywB:
undetectable		 3rc0A-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		5 / 12 VAL B 331
ALA B 352
ALA B 566
LEU B 295
TYR B 154
 None
 1.09A 3rc0B-6bywB:
undetectable		 3rc0B-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		5 / 10 PHE B 535
VAL B 395
PHE B 392
ILE B 422
PHE B 431
 None
 1.38A 3t3qB-6bywB:
undetectable		 3t3qB-6bywB:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		5 / 10 PHE B 535
VAL B 395
PHE B 392
ILE B 422
PHE B 431
 None
 1.38A 3t3qC-6bywB:
undetectable		 3t3qC-6bywB:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		3 / 3 TYR B 190
GLU B 587
TYR B 578
 None
None
TRQ  B 697 ( 3.8A)
 0.92A 3ug8A-6bywB:
undetectable		 3ug8A-6bywB:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 8 TRP B 660
PHE B 637
PRO B 591
TRP B 590
 None
 1.40A 3v35A-6bywB:
undetectable		 3v35A-6bywB:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		3 / 3 ARG B 571
ARG B 401
ASP B 394
 None
 1.01A 3wipG-6bywB:
undetectable
3wipH-6bywB:
undetectable		 3wipG-6bywB:
undetectable
3wipH-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 6 MET B 371
MET B 592
LEU B 621
ILE B   8
 None
 0.96A 4okxA-6bywB:
undetectable		 4okxA-6bywB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 5 TYR B 154
PHE B 619
LEU B 616
PRO B  11
 None
 0.80A 5csyB-6bywB:
undetectable		 5csyB-6bywB:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		3 / 3 ARG B 593
ASN B 504
ASP B 508
 None
 0.91A 5gwxA-6bywB:
undetectable		 5gwxA-6bywB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		5 / 9 ILE B 480
SER B 496
SER B 512
GLY B 511
THR B 687
 None
 1.37A 6awpA-6bywB:
undetectable		 6awpA-6bywB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H3D_A_DHIA601_0
(DUF2338
DOMAIN-CONTAINING
PROTEIN)		 6byw GOXA
(Pseudoalteromona
s
luteoviolacea) 		4 / 5 TYR B  45
ASN B 700
TYR B 361
ARG B  16
 None
MG  B 901 (-3.4A)
None
None
 1.45A 6h3dA-6bywB:
undetectable		 6h3dA-6bywB:
undetectable