SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6byx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		3 / 3 TRP A 348
VAL A 361
TRP A 358
 None
 1.34A 1c4dC-6byxA:
undetectable
1c4dD-6byxA:
undetectable		 1c4dC-6byxA:
undetectable
1c4dD-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 HIS A 341
LEU A 345
SER A 339
PRO A 285
PHE A 283
 None
 1.06A 1dfoA-6byxA:
undetectable		 1dfoA-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 HIS A 341
LEU A 345
SER A 339
PRO A 285
PHE A 283
 None
 1.05A 1dfoB-6byxA:
undetectable		 1dfoB-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 HIS A 341
LEU A 345
SER A 339
PRO A 285
PHE A 283
 None
 1.05A 1dfoC-6byxA:
undetectable		 1dfoC-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 HIS A 341
LEU A 345
SER A 339
PRO A 285
PHE A 283
 None
 1.05A 1dfoD-6byxA:
undetectable		 1dfoD-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		4 / 8 HIS A 133
HIS A 131
TYR A 169
PHE A 182
 None
 1.30A 1eqbA-6byxA:
undetectable
1eqbB-6byxA:
undetectable		 1eqbA-6byxA:
undetectable
1eqbB-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		4 / 8 TYR A 169
PHE A 182
HIS A 133
HIS A 131
 None
 1.31A 1eqbA-6byxA:
undetectable
1eqbB-6byxA:
undetectable		 1eqbA-6byxA:
undetectable
1eqbB-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		4 / 8 HIS A 133
HIS A 131
TYR A 169
PHE A 182
 None
 1.30A 1eqbC-6byxA:
undetectable
1eqbD-6byxA:
undetectable		 1eqbC-6byxA:
undetectable
1eqbD-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		4 / 8 TYR A 169
PHE A 182
HIS A 133
HIS A 131
 None
 1.31A 1eqbC-6byxA:
undetectable
1eqbD-6byxA:
undetectable		 1eqbC-6byxA:
undetectable
1eqbD-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		4 / 6 GLY A 388
GLY A 304
TYR A 303
SER A 442
 GOL  A 612 (-3.4A)
GOL  A 611 (-3.7A)
GOL  A 611 (-4.5A)
GOL  A 612 ( 4.9A)
 0.76A 1eswA-6byxA:
undetectable		 1eswA-6byxA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		4 / 7 MET A 228
PHE A 238
PHE A 283
PHE A 186
 None
 1.21A 1fxvA-6byxA:
undetectable
1fxvB-6byxA:
undetectable		 1fxvA-6byxA:
undetectable
1fxvB-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 11 LEU A 360
ALA A 337
TYR A 335
LEU A 302
GLN A 319
 None
 1.17A 1iiuA-6byxA:
undetectable		 1iiuA-6byxA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		4 / 8 VAL A 153
TYR A  94
ASP A 198
LEU A 114
 None
 1.15A 1pk2A-6byxA:
undetectable		 1pk2A-6byxA:
30.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 11 LEU A 360
ALA A 337
TYR A 335
LEU A 302
GLN A 319
 None
 1.38A 1qabE-6byxA:
undetectable		 1qabE-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 11 LEU A 360
ALA A 337
TYR A 335
LEU A 302
GLN A 319
 None
 1.13A 1rlbF-6byxA:
undetectable		 1rlbF-6byxA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 11 TYR A  94
SER A 115
VAL A 153
ALA A 152
LEU A 114
 None
 1.25A 1uduA-6byxA:
undetectable		 1uduA-6byxA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 GLY A  88
ALA A  86
ASP A  89
ALA A  90
TYR A 499
 None
 1.11A 2avdB-6byxA:
undetectable		 2avdB-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 PHE A  79
GLY A  81
HIS A 146
GLU A 144
HIS A 167
 None
 1.33A 2pgfA-6byxA:
undetectable		 2pgfA-6byxA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		4 / 5 GLY A 195
GLY A 158
PHE A  97
PHE A  99
 None
 1.07A 2qr2A-6byxA:
undetectable
2qr2B-6byxA:
undetectable		 2qr2A-6byxA:
18.06
2qr2B-6byxA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 10 TYR A 498
ILE A 489
TYR A 497
LEU A 518
VAL A  42
 None
 1.38A 2w98A-6byxA:
undetectable		 2w98A-6byxA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 ILE A  84
GLY A  88
ASP A  89
LEU A 511
TYR A 103
 None
 1.18A 2zw9A-6byxA:
3.2		 2zw9A-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		6 / 12 GLY A 494
ILE A 491
PHE A 451
ALA A 465
SER A 449
GLY A 447
 None
 1.40A 3hs6B-6byxA:
undetectable		 3hs6B-6byxA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		3 / 3 ASP A 165
GLU A 144
GLY A 135
 None
 0.62A 3w9tA-6byxA:
undetectable		 3w9tA-6byxA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 TYR A 497
ILE A  50
GLU A  45
HIS A  96
VAL A 124
 None
 1.44A 4a97A-6byxA:
undetectable
4a97B-6byxA:
undetectable		 4a97A-6byxA:
16.39
4a97B-6byxA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 PHE A 472
SER A 449
ARG A 314
HIS A 400
ILE A 402
 None
 1.14A 4krhB-6byxA:
undetectable		 4krhB-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 TYR A 303
ALA A 267
TYR A 268
GLY A 301
THR A 242
 GOL  A 611 (-4.5A)
None
None
None
None
 1.25A 4mm4A-6byxA:
undetectable		 4mm4A-6byxA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 TYR A 303
ALA A 267
TYR A 268
GLY A 301
THR A 242
 GOL  A 611 (-4.5A)
None
None
None
None
 1.26A 4mm4B-6byxA:
undetectable		 4mm4B-6byxA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 GLY A  53
LEU A 511
MET A 501
HIS A 486
ILE A  84
 None
None
None
SO4  A 608 (-4.8A)
None
 1.34A 4okbA-6byxA:
undetectable		 4okbA-6byxA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		3 / 3 MET A 166
MET A 113
TYR A 189
 None
 1.23A 4p6xI-6byxA:
undetectable		 4p6xI-6byxA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 HIS A 512
GLU A 502
PHE A 484
GLN A 478
GLY A 481
 None
 1.18A 4uilH-6byxA:
undetectable
4uilL-6byxA:
undetectable		 4uilH-6byxA:
undetectable
4uilL-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 11 GLY A 301
LEU A 302
ASP A 364
SER A 363
PHE A 317
 None
None
GOL  A 614 (-2.6A)
GOL  A 614 ( 4.7A)
None
 1.37A 4wnuC-6byxA:
undetectable		 4wnuC-6byxA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		3 / 3 ASP A 448
GLY A 467
ASP A 398
 None
 0.68A 4xdtA-6byxA:
undetectable		 4xdtA-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		4 / 5 THR A 134
GLY A 138
HIS A 146
ASP A 165
 None
 1.26A 5c0oH-6byxA:
undetectable		 5c0oH-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		4 / 6 PRO A 244
HIS A 133
ALA A  54
LEU A 511
 None
 1.05A 5igiA-6byxA:
undetectable		 5igiA-6byxA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 TYR A 476
LEU A 455
GLY A 458
PHE A 484
LEU A 500
 None
 1.30A 5jo9A-6byxA:
undetectable		 5jo9A-6byxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 6byx SHORT ULVAN LYASE
(Alteromonas
sp.
LOR) 		5 / 12 HIS A 512
LEU A 511
PRO A 460
GLY A 458
LEU A 455
 None
 1.14A 6b0lB-6byxA:
undetectable		 6b0lB-6byxA:
20.00