SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bzc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		4 / 5 GLU A 307
THR A 306
HIS A 302
LEU A 315
 None
 1.12A 1d4fC-6bzcA:
2.4		 1d4fC-6bzcA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 PHE A 473
ALA A 486
LEU A 169
LEU A 292
HIS A 302
 None
 1.26A 1qabF-6bzcA:
undetectable		 1qabF-6bzcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 PRO A 379
GLY A 380
ASN A 382
LEU A 348
ASP A 352
 None
 1.44A 2b9eA-6bzcA:
undetectable		 2b9eA-6bzcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 ILE A 135
ILE A 276
ILE A 204
LEU A 202
PHE A 130
 None
None
None
None
EDO  A 604 (-4.6A)
 1.14A 2qo5A-6bzcA:
undetectable		 2qo5A-6bzcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 ILE A 334
LEU A 484
ALA A 486
ILE A 485
PHE A 344
 None
 1.12A 3b2rA-6bzcA:
undetectable		 3b2rA-6bzcA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 11 ILE A 334
LEU A 484
ALA A 486
ILE A 485
PHE A 344
 None
 1.15A 3b2rB-6bzcA:
undetectable		 3b2rB-6bzcA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 MET A 420
LEU A 419
GLY A 380
LEU A 476
ILE A 403
 None
 1.42A 3h52A-6bzcA:
undetectable		 3h52A-6bzcA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 9 GLY A 372
ILE A 334
PHE A 487
PHE A  51
GLY A 320
 None
 1.26A 3ko0A-6bzcA:
0.5
3ko0C-6bzcA:
0.5		 3ko0A-6bzcA:
27.08
3ko0C-6bzcA:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG201_1
(PROTEIN S100-A4)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 9 GLY A 320
GLY A 372
ILE A 334
PHE A 487
PHE A  51
 None
 1.33A 3ko0F-6bzcA:
0.5
3ko0G-6bzcA:
0.6		 3ko0F-6bzcA:
27.08
3ko0G-6bzcA:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI201_1
(PROTEIN S100-A4)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 9 GLY A 320
GLY A 372
ILE A 334
PHE A 487
PHE A  51
 None
 1.32A 3ko0H-6bzcA:
0.6
3ko0I-6bzcA:
0.5		 3ko0H-6bzcA:
27.08
3ko0I-6bzcA:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 10 GLY A 320
GLY A 372
ILE A 334
PHE A 487
PHE A  51
 None
 1.21A 3ko0L-6bzcA:
0.3
3ko0N-6bzcA:
0.6		 3ko0L-6bzcA:
27.08
3ko0N-6bzcA:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 10 GLY A 372
ILE A 334
PHE A 487
PHE A  51
GLY A 320
 None
 1.25A 3ko0R-6bzcA:
0.5
3ko0T-6bzcA:
0.6		 3ko0R-6bzcA:
27.08
3ko0T-6bzcA:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NHX_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 LEU A 293
VAL A 266
MET A 127
ALA A 275
PHE A 262
 None
 1.43A 3nhxA-6bzcA:
undetectable		 3nhxA-6bzcA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 THR A 212
ASN A 218
GLY A 154
ALA A 206
ALA A 241
 G6P  A 601 (-3.1A)
None
None
None
None
 1.15A 3p5nB-6bzcA:
undetectable		 3p5nB-6bzcA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 9 LEU A 348
ASP A 352
GLY A 320
ILE A 334
ILE A 375
 None
 1.00A 3s56B-6bzcA:
undetectable		 3s56B-6bzcA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 THR A 466
GLN A 426
PHE A 387
HIS A 392
GLN A 349
 GOL  A 605 ( 4.6A)
None
None
None
None
 1.24A 3v3oA-6bzcA:
undetectable		 3v3oA-6bzcA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		4 / 5 ILE A 334
ILE A 492
TYR A 488
GLU A 489
 None
 1.18A 4a99D-6bzcA:
undetectable		 4a99D-6bzcA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 HIS A  98
SER A 355
GLY A 496
SER A 503
VAL A 497
 None
 1.16A 4danA-6bzcA:
2.4
4danB-6bzcA:
3.1		 4danA-6bzcA:
16.60
4danB-6bzcA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 VAL A 150
ILE A 204
PHE A 239
ILE A 254
PHE A 130
 None
None
None
None
EDO  A 604 (-4.6A)
 1.21A 5b8iC-6bzcA:
undetectable		 5b8iC-6bzcA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 ILE A 485
ALA A 486
GLY A 295
GLY A 161
VAL A 165
 None
 1.17A 5i71A-6bzcA:
undetectable		 5i71A-6bzcA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 ILE A 485
ALA A 486
GLY A 295
GLY A 161
VAL A 165
 None
 1.20A 5i75A-6bzcA:
undetectable		 5i75A-6bzcA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 GLY A 186
PHE A 203
ALA A 222
SER A 158
ILE A 155
 None
None
None
G6P  A 601 (-2.6A)
None
 1.25A 5ih0A-6bzcA:
undetectable		 5ih0A-6bzcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		3 / 3 GLY A 267
GLY A 268
GLN A 506
 None
G6P  A 601 ( 3.9A)
G6P  A 601 ( 4.2A)
 0.36A 5imsA-6bzcA:
4.8		 5imsA-6bzcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		5 / 12 LEU A 476
GLY A 161
ALA A 168
LEU A 341
GLY A 277
 None
 0.96A 5kb5A-6bzcA:
undetectable		 5kb5A-6bzcA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		4 / 6 SER A 158
ALA A 275
SER A 274
ALA A 206
 G6P  A 601 (-2.6A)
None
None
None
 0.78A 6bocA-6bzcA:
undetectable
6bocB-6bzcA:
undetectable
6bocC-6bzcA:
undetectable
6bocD-6bzcA:
undetectable		 6bocA-6bzcA:
undetectable
6bocB-6bzcA:
undetectable
6bocC-6bzcA:
undetectable
6bocD-6bzcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		4 / 7 TYR A 369
TRP A  14
CYH A  73
LEU A  69
 None
 1.28A 6cnjA-6bzcA:
undetectable
6cnjB-6bzcA:
0.5		 6cnjA-6bzcA:
24.75
6cnjB-6bzcA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		4 / 8 TYR A 369
TRP A  14
CYH A  73
LEU A  69
 None
 1.37A 6cnjD-6bzcA:
undetectable
6cnjE-6bzcA:
2.0		 6cnjD-6bzcA:
24.75
6cnjE-6bzcA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_B_NCTB402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		4 / 7 TYR A 369
TRP A  14
CYH A  73
LEU A  69
 None
 1.27A 6cnkB-6bzcA:
undetectable
6cnkC-6bzcA:
undetectable		 6cnkB-6bzcA:
24.75
6cnkC-6bzcA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 6bzc GLUCOSE-6-PHOSPHATE
ISOMERASE
(Elizabethkingia
anophelis) 		3 / 3 HIS A 171
ASN A 409
LEU A 476
 None
 0.72A 6f7lB-6bzcA:
undetectable		 6f7lB-6bzcA:
undetectable