SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bzg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 6bzg PROTEIN ZIP2
SPORULATION-SPECIFIC
PROTEIN 16
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 149
SER A 148
ASP B 572
LYS B 568
 None
 1.26A 1hwiC-6bzgA:
undetectable		 1hwiC-6bzgA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 6bzg PROTEIN ZIP2
SPORULATION-SPECIFIC
PROTEIN 16
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 149
SER A 148
ASP B 572
LYS B 568
 None
 1.26A 1hwiD-6bzgA:
undetectable		 1hwiD-6bzgA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 6bzg SPORULATION-SPECIFIC
PROTEIN 16
(Saccharomyces
cerevisiae) 		4 / 5 VAL A  62
ASN A  61
VAL A  28
ILE A  11
 None
 0.94A 1z2bC-6bzgA:
undetectable		 1z2bC-6bzgA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 6bzg PROTEIN ZIP2
SPORULATION-SPECIFIC
PROTEIN 16
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 654
GLY B 655
MET A 151
VAL A 149
THR B 689
 None
 1.30A 1z95A-6bzgB:
undetectable		 1z95A-6bzgB:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 6bzg PROTEIN ZIP2
(Saccharomyces
cerevisiae) 		4 / 7 TYR B 637
LEU B 659
LYS B 663
SER B 544
 None
 1.20A 3lslA-6bzgB:
undetectable
3lslD-6bzgB:
undetectable		 3lslA-6bzgB:
undetectable
3lslD-6bzgB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 6bzg PROTEIN ZIP2
SPORULATION-SPECIFIC
PROTEIN 16
(Saccharomyces
cerevisiae) 		5 / 12 TYR B 604
GLU A 130
PHE A 135
VAL A  23
ILE A  14
 None
 1.42A 4a99A-6bzgB:
undetectable
4a99C-6bzgB:
undetectable		 4a99A-6bzgB:
11.20
4a99C-6bzgB:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 6bzg SPORULATION-SPECIFIC
PROTEIN 16
(Saccharomyces
cerevisiae) 		4 / 4 ASN A  83
SER A 101
LEU A  98
THR A  85
 None
 1.47A 4an2A-6bzgA:
undetectable		 4an2A-6bzgA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 6bzg PROTEIN ZIP2
(Saccharomyces
cerevisiae) 		4 / 5 ALA B 631
ILE B 503
LEU B 526
LYS B 501
 None
 1.22A 4g19A-6bzgB:
undetectable		 4g19A-6bzgB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 6bzg PROTEIN ZIP2
(Saccharomyces
cerevisiae) 		3 / 3 LEU B 688
MET B 693
ASP B 649
 None
 0.76A 4j7xB-6bzgB:
3.2		 4j7xB-6bzgB:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 6bzg PROTEIN ZIP2
SPORULATION-SPECIFIC
PROTEIN 16
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 654
GLY B 655
MET A 151
VAL A 149
THR B 689
 None
 1.34A 4ojbA-6bzgB:
undetectable		 4ojbA-6bzgB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 6bzg PROTEIN ZIP2
SPORULATION-SPECIFIC
PROTEIN 16
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 654
GLY B 655
MET A 151
VAL A 149
THR B 689
 None
 1.35A 4okbA-6bzgB:
undetectable		 4okbA-6bzgB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 6bzg PROTEIN ZIP2
SPORULATION-SPECIFIC
PROTEIN 16
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 654
GLY B 655
MET A 151
VAL A 149
THR B 689
 None
 1.32A 4okwA-6bzgB:
undetectable		 4okwA-6bzgB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 6bzg PROTEIN ZIP2
SPORULATION-SPECIFIC
PROTEIN 16
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 654
GLY B 655
MET A 151
VAL A 149
THR B 689
 None
 1.35A 4okxA-6bzgB:
undetectable		 4okxA-6bzgB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 6bzg PROTEIN ZIP2
SPORULATION-SPECIFIC
PROTEIN 16
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 654
GLY B 655
MET A 151
VAL A 149
THR B 689
 None
 1.35A 4olmA-6bzgB:
undetectable		 4olmA-6bzgB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 6bzg SPORULATION-SPECIFIC
PROTEIN 16
PROTEIN ZIP2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 MET B 556
ASP B 594
ARG A 125
 None
 1.06A 5z6jA-6bzgB:
undetectable		 5z6jA-6bzgB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_A_NCTA405_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4)		 6bzg PROTEIN ZIP2
SPORULATION-SPECIFIC
PROTEIN 16
(Saccharomyces
cerevisiae) 		4 / 6 TRP B 599
THR A 121
CYH A  25
THR A 118
 None
 1.40A 6cnkA-6bzgB:
undetectable
6cnkB-6bzgB:
undetectable		 6cnkA-6bzgB:
20.00
6cnkB-6bzgB:
20.00