SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bzh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 6bzh PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58
(Mus
musculus) 		3 / 3 LEU A 124
ASN A 121
ARG A 140
 None
 0.88A 2qhfA-6bzhA:
undetectable		 2qhfA-6bzhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 6bzh PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58
(Mus
musculus) 		3 / 3 GLU A  37
GLN A  65
ARG A   6
 None
 0.97A 2w3bB-6bzhA:
undetectable		 2w3bB-6bzhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 6bzh PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58
(Mus
musculus) 		4 / 5 LEU A 124
ARG A 143
ARG A 140
ARG A 148
 None
 1.29A 3ticA-6bzhA:
undetectable		 3ticA-6bzhA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 6bzh PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58
(Mus
musculus) 		4 / 6 TYR A  15
ARG A 104
ASP A  93
LEU A 100
 None
 1.21A 4ax8A-6bzhA:
undetectable		 4ax8A-6bzhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 6bzh PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58
(Mus
musculus) 		4 / 6 ASP A  21
ASN A  46
ALA A  43
TYR A  40
 None
 1.22A 4mdbA-6bzhA:
undetectable		 4mdbA-6bzhA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 6bzh PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58
(Mus
musculus) 		4 / 7 GLY A  49
ARG A 161
TYR A  24
ALA A  53
 None
 0.70A 5e26A-6bzhA:
undetectable
5e26B-6bzhA:
undetectable		 5e26A-6bzhA:
undetectable
5e26B-6bzhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 6bzh PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58
(Mus
musculus) 		4 / 8 TYR A  24
ALA A  53
GLY A  49
ARG A 161
 None
 0.72A 5e26C-6bzhA:
undetectable
5e26D-6bzhA:
undetectable		 5e26C-6bzhA:
undetectable
5e26D-6bzhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 6bzh PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58
(Mus
musculus) 		4 / 8 LEU A  77
ILE A  97
ALA A  54
LEU A  58
 None
 0.72A 5y7pC-6bzhA:
undetectable		 5y7pC-6bzhA:
undetectable