SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bzy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 6bzy 22D11 HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 117
PRO H 147
THR H 116
PRO H 118
 None
 1.34A 1dsdC-6bzyH:
undetectable		 1dsdC-6bzyH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 6bzy 22D11 HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 117
PRO H 147
THR H 116
PRO H 118
 None
 1.34A 1dsdC-6bzyH:
undetectable		 1dsdC-6bzyH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6bzy 22D11 HEAVY CHAIN
(Mus
musculus) 		3 / 3 GLU H 192
THR H 188
LEU H 159
 None
 0.61A 1v8bC-6bzyH:
undetectable		 1v8bC-6bzyH:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 6bzy 22D11 HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER H 204
ALA H 199
VAL H 198
 None
 0.52A 5xiwC-6bzyH:
undetectable		 5xiwC-6bzyH:
22.12