SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c0d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		4 / 5 LEU A 163
LEU A  35
SER A  82
GLY A  63
 None
 0.94A 1a4lC-6c0dA:
undetectable		 1a4lC-6c0dA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		4 / 4 ALA A 238
VAL A 241
ALA A 242
HIS A 312
 None
None
None
EDO  A 507 (-4.2A)
 1.05A 1q23A-6c0dA:
2.7		 1q23A-6c0dA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		4 / 4 ALA A 238
VAL A 241
ALA A 242
HIS A 312
 None
None
None
EDO  A 507 (-4.2A)
 1.07A 1q23F-6c0dA:
undetectable		 1q23F-6c0dA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		4 / 8 THR A  87
GLY A  89
GLN A 191
PRO A  28
 None
 0.98A 1rxcI-6c0dA:
10.5		 1rxcI-6c0dA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 11 LEU A  20
ILE A  98
ARG A  43
VAL A 120
GLY A  79
 None
 1.39A 2bxeA-6c0dA:
undetectable		 2bxeA-6c0dA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 12 ALA A 342
ASP A 343
PRO A 376
VAL A 375
ILE A 202
 None
SO4  A 504 (-4.1A)
EDO  A 509 ( 4.5A)
None
None
 1.25A 2o4lA-6c0dA:
undetectable		 2o4lA-6c0dA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_E_MTXE621_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 12 ALA A 411
LEU A 334
LEU A  76
ILE A 368
ARG A 180
 None
 0.99A 2oipE-6c0dA:
undetectable		 2oipE-6c0dA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 11 GLY A  61
ASP A  60
ARG A 173
ILE A 144
LEU A 134
 None
 1.33A 3bexC-6c0dA:
undetectable
3bexD-6c0dA:
undetectable		 3bexC-6c0dA:
undetectable
3bexD-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 10 LEU A 134
GLY A  61
ASP A  60
ARG A 173
ILE A 144
 None
 1.33A 3bexC-6c0dA:
undetectable
3bexD-6c0dA:
undetectable		 3bexC-6c0dA:
undetectable
3bexD-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 10 GLY A  61
ASP A  60
ARG A 173
ILE A 144
LEU A 134
 None
 1.32A 3bexE-6c0dA:
undetectable
3bexF-6c0dA:
undetectable		 3bexE-6c0dA:
undetectable
3bexF-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 11 LEU A 134
GLY A  61
ASP A  60
ARG A 173
ILE A 144
 None
 1.33A 3bexE-6c0dA:
undetectable
3bexF-6c0dA:
undetectable		 3bexE-6c0dA:
undetectable
3bexF-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 11 GLY A  61
ASP A  60
ARG A 173
ILE A 144
LEU A 134
 None
 1.31A 3bf1A-6c0dA:
undetectable
3bf1B-6c0dA:
undetectable		 3bf1A-6c0dA:
undetectable
3bf1B-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 11 GLY A  61
ASP A  60
ARG A 173
ILE A 144
LEU A 134
 None
 1.32A 3bf1C-6c0dA:
undetectable
3bf1D-6c0dA:
undetectable		 3bf1C-6c0dA:
undetectable
3bf1D-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 11 LEU A 134
GLY A  61
ASP A  60
ARG A 173
ILE A 144
 None
 1.36A 3bf1C-6c0dA:
undetectable
3bf1D-6c0dA:
undetectable		 3bf1C-6c0dA:
undetectable
3bf1D-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 11 GLY A  61
ASP A  60
ARG A 173
ILE A 144
LEU A 134
 None
 1.31A 3bf1E-6c0dA:
undetectable
3bf1F-6c0dA:
undetectable		 3bf1E-6c0dA:
undetectable
3bf1F-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 11 LEU A 134
GLY A  61
ASP A  60
ARG A 173
ILE A 144
 None
 1.34A 3bf1E-6c0dA:
undetectable
3bf1F-6c0dA:
undetectable		 3bf1E-6c0dA:
undetectable
3bf1F-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 9 ALA A 342
ASP A 343
PRO A 376
VAL A 375
ILE A 202
 None
SO4  A 504 (-4.1A)
EDO  A 509 ( 4.5A)
None
None
 1.17A 3em4B-6c0dA:
undetectable		 3em4B-6c0dA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 10 ILE A  78
PRO A 187
SER A  80
GLY A  79
LEU A  76
 None
None
ZN  A 501 ( 4.8A)
None
None
 1.35A 3ik6B-6c0dA:
undetectable
3ik6E-6c0dA:
undetectable		 3ik6B-6c0dA:
13.77
3ik6E-6c0dA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 12 GLY A  89
ALA A  94
ALA A  25
ILE A 189
PRO A  28
 None
 1.03A 3jayA-6c0dA:
undetectable		 3jayA-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 11 LEU A 163
ASP A  60
LEU A 134
ILE A 144
SER A 138
 None
 1.30A 3o94D-6c0dA:
undetectable		 3o94D-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 11 ALA A 342
ASP A 343
PRO A 376
VAL A 375
ILE A 202
 None
SO4  A 504 (-4.1A)
EDO  A 509 ( 4.5A)
None
None
 1.23A 3oxxB-6c0dA:
undetectable		 3oxxB-6c0dA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 10 ALA A 162
LEU A 134
LEU A  35
LEU A 168
ILE A 124
 None
 1.05A 3wdmD-6c0dA:
undetectable		 3wdmD-6c0dA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		4 / 7 ASP A  83
GLY A  88
THR A  87
SER A  34
 None
 0.99A 4ac9C-6c0dA:
3.6		 4ac9C-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		3 / 3 GLN A 335
THR A 207
THR A 329
 None
 0.79A 4fu9A-6c0dA:
undetectable		 4fu9A-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		3 / 3 GLN A 335
THR A 207
THR A 329
 None
 0.80A 4fufA-6c0dA:
undetectable		 4fufA-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 12 GLY A  61
ASP A  60
ARG A 173
ILE A 144
LEU A 134
 None
 1.29A 4o5fA-6c0dA:
undetectable
4o5fB-6c0dA:
undetectable		 4o5fA-6c0dA:
undetectable
4o5fB-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 12 LEU A 134
GLY A  61
ASP A  60
ARG A 173
ILE A 144
 None
 1.28A 4o5fA-6c0dA:
undetectable
4o5fB-6c0dA:
undetectable		 4o5fA-6c0dA:
undetectable
4o5fB-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 12 GLU A 186
GLU A 127
ASP A  92
LEU A  20
GLY A  96
 None
ZN  A 501 ( 4.9A)
ZN  A 501 (-2.8A)
None
None
 1.42A 4pgfB-6c0dA:
undetectable		 4pgfB-6c0dA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 11 HIS A  81
ASP A  92
GLU A 126
GLU A 127
GLY A 356
 ZN  A 501 (-3.3A)
ZN  A 501 (-2.8A)
ZN  A 501 ( 4.0A)
ZN  A 501 ( 4.9A)
None
 0.50A 4pqaA-6c0dA:
28.5		 4pqaA-6c0dA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 9 ILE A  78
LEU A 345
VAL A 204
LEU A 373
ILE A 202
 None
 1.26A 4r38C-6c0dA:
undetectable		 4r38C-6c0dA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		3 / 3 ASP A  60
LEU A 134
GLY A 135
 None
 0.53A 4xmfA-6c0dA:
undetectable		 4xmfA-6c0dA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		3 / 3 LEU A  46
ARG A  32
ARG A  43
 None
 0.84A 4yiaB-6c0dA:
undetectable		 4yiaB-6c0dA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 12 GLY A  61
ASP A  60
ARG A 173
ILE A 144
LEU A 134
 None
 1.25A 5b8hA-6c0dA:
undetectable
5b8hB-6c0dA:
undetectable		 5b8hA-6c0dA:
undetectable
5b8hB-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 12 LEU A 134
GLY A  61
ASP A  60
ARG A 173
ILE A 144
 None
 1.23A 5b8hA-6c0dA:
undetectable
5b8hB-6c0dA:
undetectable		 5b8hA-6c0dA:
undetectable
5b8hB-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 12 VAL A  77
ASP A 119
ALA A 183
ARG A 180
GLY A  73
 None
 1.24A 5m54E-6c0dA:
3.0		 5m54E-6c0dA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		6 / 9 LEU A  91
GLY A  89
GLY A  29
LEU A  17
LEU A  20
ALA A  94
 None
 1.27A 5o96A-6c0dA:
undetectable
5o96B-6c0dA:
undetectable		 5o96A-6c0dA:
undetectable
5o96B-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 10 LEU A  91
GLY A  89
GLY A  29
LEU A  17
ALA A  94
 None
 1.05A 5o96G-6c0dA:
undetectable
5o96H-6c0dA:
undetectable		 5o96G-6c0dA:
undetectable
5o96H-6c0dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		4 / 6 ASP A   9
ARG A  12
LEU A  13
ASP A  16
 EDO  A 510 (-3.0A)
EDO  A 511 ( 4.5A)
None
None
 0.94A 5tdzA-6c0dA:
undetectable		 5tdzA-6c0dA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 12 VAL A 363
ARG A  43
GLY A  63
THR A 129
GLY A 128
 None
 1.18A 6brdC-6c0dA:
2.5		 6brdC-6c0dA:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		5 / 12 ALA A 342
ASP A 343
PRO A 376
VAL A 375
ILE A 202
 None
SO4  A 504 (-4.1A)
EDO  A 509 ( 4.5A)
None
None
 1.22A 6difA-6c0dA:
undetectable		 6difA-6c0dA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY
(Paraburkholderia
phymatum) 		4 / 7 SER A  69
ALA A  75
ILE A 408
ALA A 405
 None
 0.93A 6ma7A-6c0dA:
undetectable		 6ma7A-6c0dA:
19.28