SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c0f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 6c0f RIBOSOMAL
RNA-PROCESSING
PROTEIN 15
RIBOSOME BIOGENESIS
PROTEIN SSF1
(Saccharomyces
cerevisiae) 		4 / 8 GLN w 205
LEU w 202
LEU v 140
SER v 185
 None
 1.19A 1hk2A-6c0fw:
undetectable		 1hk2A-6c0fw:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 6c0f RIBOSOME PRODUCTION
FACTOR 1
(Saccharomyces
cerevisiae) 		4 / 6 PHE I 110
ILE I 150
VAL I 148
PHE I 162
 None
 0.87A 2cizA-6c0fI:
undetectable		 2cizA-6c0fI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 6c0f RIBOSOME BIOGENESIS
PROTEIN SSF1
(Saccharomyces
cerevisiae) 		4 / 6 ILE v 172
SER v  25
ILE v  50
PHE v 190
 None
 1.09A 2q72A-6c0fv:
undetectable		 2q72A-6c0fv:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 6c0f RIBOSOME BIOGENESIS
PROTEIN BRX1
(Saccharomyces
cerevisiae) 		4 / 8 HIS b  45
TYR b 113
THR b 222
GLN b 115
 None
 1.36A 2vxaF-6c0fb:
undetectable
2vxaG-6c0fb:
undetectable
2vxaI-6c0fb:
undetectable		 2vxaF-6c0fb:
26.19
2vxaG-6c0fb:
26.19
2vxaI-6c0fb:
26.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 6c0f PROTEASOME-INTERACTI
NG PROTEIN CIC1
(Saccharomyces
cerevisiae) 		4 / 7 ASP K 261
VAL K  37
ARG K  34
ILE K  38
 None
 1.03A 2yfbA-6c0fK:
undetectable		 2yfbA-6c0fK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 6c0f PROTEASOME-INTERACTI
NG PROTEIN CIC1
(Saccharomyces
cerevisiae) 		5 / 12 LEU K 190
THR K 188
ASP K 183
ALA K 182
ILE K 180
 None
C  6   5 ( 2.9A)
None
None
None
 1.21A 3a3bA-6c0fK:
undetectable		 3a3bA-6c0fK:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 6c0f RIBOSOME PRODUCTION
FACTOR 1
(Saccharomyces
cerevisiae) 		4 / 6 ILE I 140
LYS I 133
ILE I 274
HIS I 164
 None
 1.15A 3eteA-6c0fI:
undetectable
3eteE-6c0fI:
undetectable		 3eteA-6c0fI:
8.54
3eteE-6c0fI:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 6c0f RIBOSOME PRODUCTION
FACTOR 1
(Saccharomyces
cerevisiae) 		4 / 7 LYS I 133
ILE I 274
HIS I 164
ILE I 140
 None
 1.12A 3eteD-6c0fI:
undetectable
3eteF-6c0fI:
undetectable		 3eteD-6c0fI:
8.54
3eteF-6c0fI:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 6c0f RIBOSOME PRODUCTION
FACTOR 1
(Saccharomyces
cerevisiae) 		3 / 3 ASN I 234
ASP I 237
ARG I 272
 None
 0.74A 3k13C-6c0fI:
undetectable		 3k13C-6c0fI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 6c0f RIBOSOME BIOGENESIS
PROTEIN BRX1
(Saccharomyces
cerevisiae) 		3 / 3 SER b  38
SER b  37
HIS b  94
 None
None
U  1 286 ( 4.0A)
 0.78A 3mzeA-6c0fb:
undetectable		 3mzeA-6c0fb:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 6c0f PROTEASOME-INTERACTI
NG PROTEIN CIC1
(Saccharomyces
cerevisiae) 		5 / 12 SER K 105
GLN K 143
THR K 223
ILE K 149
SER K 146
 None
 1.37A 4c49D-6c0fK:
undetectable		 4c49D-6c0fK:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 6c0f RIBOSOME BIOGENESIS
PROTEIN SSF1
(Saccharomyces
cerevisiae) 		5 / 12 LEU v 339
ILE v 342
HIS v 353
GLU v 355
ASP v 158
 None
 1.39A 4r88B-6c0fv:
undetectable		 4r88B-6c0fv:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 6c0f RIBOSOME BIOGENESIS
PROTEIN SSF1
(Saccharomyces
cerevisiae) 		5 / 12 LEU v 339
ILE v 342
HIS v 353
GLU v 355
ASP v 158
 None
 1.40A 4r88C-6c0fv:
undetectable		 4r88C-6c0fv:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 6c0f RIBOSOME BIOGENESIS
PROTEIN SSF1
(Saccharomyces
cerevisiae) 		5 / 12 LEU v 339
ILE v 342
HIS v 353
GLU v 355
ASP v 158
 None
 1.37A 4r88D-6c0fv:
undetectable		 4r88D-6c0fv:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 6c0f RIBOSOME BIOGENESIS
PROTEIN SSF1
(Saccharomyces
cerevisiae) 		5 / 12 LEU v 339
ILE v 342
HIS v 353
GLU v 355
ASP v 158
 None
 1.40A 4r88E-6c0fv:
undetectable		 4r88E-6c0fv:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 6c0f RIBOSOME BIOGENESIS
PROTEIN SSF1
(Saccharomyces
cerevisiae) 		5 / 12 LEU v 339
ILE v 342
HIS v 353
GLU v 355
ASP v 158
 None
 1.40A 4r88F-6c0fv:
undetectable		 4r88F-6c0fv:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 6c0f RIBOSOME PRODUCTION
FACTOR 1
(Saccharomyces
cerevisiae) 		3 / 3 TYR I 172
LYS I 174
LYS I 268
 None
 1.17A 5dbyA-6c0fI:
2.6		 5dbyA-6c0fI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 6c0f RIBOSOME PRODUCTION
FACTOR 1
(Saccharomyces
cerevisiae) 		3 / 3 THR I  99
ALA I 103
ASN I 100
 None
 0.30A 5ersA-6c0fI:
undetectable		 5ersA-6c0fI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 6c0f PROTEASOME-INTERACTI
NG PROTEIN CIC1
(Saccharomyces
cerevisiae) 		3 / 3 PRO K 256
ARG K 255
GLU K 257
 None
 0.95A 5j6hA-6c0fK:
undetectable		 5j6hA-6c0fK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 6c0f PROTEASOME-INTERACTI
NG PROTEIN CIC1
(Saccharomyces
cerevisiae) 		4 / 7 LEU K  74
TRP K 253
GLU K 203
SER K 178
 None
 1.27A 5umwA-6c0fK:
undetectable
5umwF-6c0fK:
undetectable		 5umwA-6c0fK:
19.54
5umwF-6c0fK:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW3_A_ACTA404_0
(FERREDOXIN--NADP
REDUCTASE)		 6c0f PROTEASOME-INTERACTI
NG PROTEIN CIC1
(Saccharomyces
cerevisiae) 		4 / 4 GLN K 233
LEU K 100
ASN K 101
GLN K 269
 None
None
U  6  19 ( 4.9A)
None
 1.32A 5vw3A-6c0fK:
undetectable		 5vw3A-6c0fK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 6c0f RIBOSOME BIOGENESIS
PROTEIN BRX1
(Saccharomyces
cerevisiae) 		5 / 12 ILE b 152
PHE b 112
PHE b  89
LEU b  55
LEU b 156
 None
 1.29A 5xxiA-6c0fb:
undetectable		 5xxiA-6c0fb:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 6c0f RIBOSOME BIOGENESIS
PROTEIN SSF1
RIBOSOMAL
RNA-PROCESSING
PROTEIN 15
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 LEU v 183
GLN w 205
LYS v 324
 None
 0.98A 6exiB-6c0fv:
undetectable		 6exiB-6c0fv:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 6c0f PROTEASOME-INTERACTI
NG PROTEIN CIC1
(Saccharomyces
cerevisiae) 		5 / 12 LEU K 124
GLU K 153
LEU K 127
GLY K 157
PHE K 173
 None
None
None
U  6   6 ( 4.0A)
None
 1.14A 6gbnB-6c0fK:
undetectable		 6gbnB-6c0fK:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6c0f RIBOSOME PRODUCTION
FACTOR 1
(Saccharomyces
cerevisiae) 		4 / 7 ILE I 117
LEU I 114
THR I 264
LEU I 265
 None
 0.93A 6nmpA-6c0fI:
undetectable
6nmpJ-6c0fI:
undetectable		 6nmpA-6c0fI:
undetectable
6nmpJ-6c0fI:
undetectable