SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c0m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		3 / 3 LEU A 484
SER A 510
ASN A 517
 None
 0.82A 1bx4A-6c0mA:
undetectable		 1bx4A-6c0mA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		4 / 6 PHE A 311
GLU A 341
LEU A 340
VAL A 378
 None
 0.94A 1hk1A-6c0mA:
undetectable		 1hk1A-6c0mA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		4 / 7 PHE A 311
GLU A 341
LEU A 340
VAL A 378
 None
 0.95A 1hk3A-6c0mA:
undetectable		 1hk3A-6c0mA:
8.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3E_A_ZMRA1200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		9 / 10 ARG A 192
THR A 193
GLU A 276
TYR A 319
TYR A 337
PHE A 372
GLU A 409
ARG A 424
ARG A 502
 8LM  A 610 (-3.3A)
8LM  A 610 ( 4.6A)
8LM  A 610 (-2.8A)
8LM  A 610 (-3.3A)
8LM  A 610 (-4.5A)
None
8LM  A 610 (-3.9A)
8LM  A 610 (-3.7A)
8LM  A 610 (-2.9A)
 0.58A 1v3eA-6c0mA:
68.9		 1v3eA-6c0mA:
98.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3E_B_ZMRB2200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		9 / 10 ARG A 192
THR A 193
GLU A 276
TYR A 319
TYR A 337
PHE A 372
GLU A 409
ARG A 424
ARG A 502
 8LM  A 610 (-3.3A)
8LM  A 610 ( 4.6A)
8LM  A 610 (-2.8A)
8LM  A 610 (-3.3A)
8LM  A 610 (-4.5A)
None
8LM  A 610 (-3.9A)
8LM  A 610 (-3.7A)
8LM  A 610 (-2.9A)
 0.68A 1v3eB-6c0mA:
68.7		 1v3eB-6c0mA:
98.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		4 / 7 LYS A 395
LEU A 394
LEU A 268
PHE A 334
 None
 1.05A 2einC-6c0mA:
undetectable
2einJ-6c0mA:
undetectable		 2einC-6c0mA:
undetectable
2einJ-6c0mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		5 / 12 ARG A 192
GLU A 276
TYR A 337
GLU A 409
ARG A 424
 8LM  A 610 (-3.3A)
8LM  A 610 (-2.8A)
8LM  A 610 (-4.5A)
8LM  A 610 (-3.9A)
8LM  A 610 (-3.7A)
 1.08A 2f0zA-6c0mA:
27.5		 2f0zA-6c0mA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		5 / 12 GLU A 276
TYR A 337
GLU A 409
ARG A 424
ARG A 502
 8LM  A 610 (-2.8A)
8LM  A 610 (-4.5A)
8LM  A 610 (-3.9A)
8LM  A 610 (-3.7A)
8LM  A 610 (-2.9A)
 0.57A 2f0zA-6c0mA:
27.5		 2f0zA-6c0mA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		3 / 3 GLY A 227
ARG A 242
TYR A 203
 None
8LM  A 611 (-3.7A)
None
 0.87A 2opxA-6c0mA:
undetectable		 2opxA-6c0mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		5 / 12 ILE A 437
ILE A 436
GLY A 488
PRO A 153
ARG A 411
 None
 0.98A 3em0B-6c0mA:
0.7		 3em0B-6c0mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		4 / 8 ASN A 208
THR A 193
SER A 257
ASN A 252
 None
8LM  A 610 ( 4.6A)
None
None
 1.07A 3kp2A-6c0mA:
undetectable
3kp2B-6c0mA:
undetectable		 3kp2A-6c0mA:
undetectable
3kp2B-6c0mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		5 / 10 ILE A 521
ASN A 551
ALA A 528
ASN A 504
LEU A 496
 None
 1.22A 3o02A-6c0mA:
undetectable
3o02B-6c0mA:
undetectable		 3o02A-6c0mA:
16.46
3o02B-6c0mA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		3 / 3 ASN A 345
GLU A 346
ARG A 376
 None
 1.02A 3wxoA-6c0mA:
undetectable		 3wxoA-6c0mA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		3 / 3 TYR A 337
ARG A 424
SER A 408
 8LM  A 610 (-4.5A)
8LM  A 610 (-3.7A)
None
 0.94A 4khpI-6c0mA:
undetectable
4khpJ-6c0mA:
undetectable		 4khpI-6c0mA:
18.55
4khpJ-6c0mA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		5 / 12 ARG A 515
ILE A 567
PRO A 568
LEU A 484
THR A 531
 None
 1.07A 4m6kA-6c0mA:
undetectable		 4m6kA-6c0mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		5 / 11 ASN A 379
VAL A 378
TYR A 280
LEU A 268
ALA A 317
 None
None
None
None
CA  A 601 ( 4.9A)
 1.47A 4m83A-6c0mA:
undetectable		 4m83A-6c0mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		3 / 3 PHE A 563
THR A 557
LEU A 526
 None
 0.78A 4qztA-6c0mA:
undetectable		 4qztA-6c0mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		4 / 8 GLN A 313
GLY A 339
ILE A 285
ASP A 279
 None
None
None
CA  A 601 (-3.4A)
 1.02A 5vlmH-6c0mA:
undetectable		 5vlmH-6c0mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6c0m HEMAGGLUTININ-NEURAM
INIDASE
(Human
respirovirus
3) 		4 / 6 LYS A 395
LEU A 394
LEU A 268
PHE A 334
 None
 1.10A 5w97C-6c0mA:
undetectable
5w97J-6c0mA:
undetectable		 5w97C-6c0mA:
undetectable
5w97J-6c0mA:
undetectable