SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c0w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ALA B  83
VAL B  81
TRP A  86
 ALA  B  83 ( 0.0A)
VAL  B  81 ( 0.6A)
TRP  A  86 ( 0.5A)
 0.79A 1av2C-6c0wB:
undetectable
1av2D-6c0wB:
undetectable		 1av2C-6c0wB:
undetectable
1av2D-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens) 		5 / 11 PHE A 106
ARG B  36
ALA B  33
LEU B  37
ALA B  38
 PHE  A 106 ( 1.3A)
ARG  B  36 ( 0.6A)
ALA  B  33 ( 0.0A)
LEU  B  37 ( 0.6A)
ALA  B  38 ( 0.0A)
 1.33A 1jb0B-6c0wA:
undetectable		 1jb0B-6c0wA:
5.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ALA B  83
VAL B  81
TRP A  86
 ALA  B  83 ( 0.0A)
VAL  B  81 ( 0.6A)
TRP  A  86 ( 0.5A)
 0.69A 1nt6A-6c0wB:
undetectable		 1nt6A-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ALA B  83
VAL B  81
TRP A  86
 ALA  B  83 ( 0.0A)
VAL  B  81 ( 0.6A)
TRP  A  86 ( 0.5A)
 0.69A 1nt6B-6c0wB:
undetectable		 1nt6B-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6c0w CENTROMERE PROTEIN N
(Homo
sapiens) 		5 / 12 THR K 163
SER K 164
LEU K 112
VAL K 119
ALA K 136
 THR  K 163 ( 0.8A)
SER  K 164 ( 0.0A)
LEU  K 112 ( 0.6A)
VAL  K 119 ( 0.6A)
ALA  K 136 ( 0.0A)
 1.48A 1q23D-6c0wK:
2.7
1q23E-6c0wK:
undetectable		 1q23D-6c0wK:
15.28
1q23E-6c0wK:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ALA B  83
VAL B  81
TRP A  86
 ALA  B  83 ( 0.0A)
VAL  B  81 ( 0.6A)
TRP  A  86 ( 0.5A)
 0.78A 1w5uC-6c0wB:
undetectable
1w5uD-6c0wB:
undetectable		 1w5uC-6c0wB:
undetectable
1w5uD-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens) 		5 / 12 LEU B  58
ALA B  33
LEU A  61
LEU A 102
VAL A 103
 LEU  B  58 ( 0.6A)
ALA  B  33 ( 0.0A)
LEU  A  61 ( 0.6A)
LEU  A 102 ( 0.6A)
VAL  A 103 ( 0.6A)
 1.05A 2c12C-6c0wB:
undetectable		 2c12C-6c0wB:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_2
(NEURAMINIDASE)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens) 		4 / 5 LEU A  61
ARG B  35
ARG B  36
ILE B  46
 LEU  A  61 ( 0.6A)
ARG  B  35 ( 0.6A)
ARG  B  36 ( 0.6A)
ILE  B  46 ( 0.7A)
 1.41A 2cmlB-6c0wA:
undetectable		 2cmlB-6c0wA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_2
(NEURAMINIDASE)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens) 		4 / 5 LEU A  61
ARG B  35
ARG B  36
ILE B  46
 LEU  A  61 ( 0.6A)
ARG  B  35 ( 0.6A)
ARG  B  36 ( 0.6A)
ILE  B  46 ( 0.7A)
 1.41A 2cmlC-6c0wA:
undetectable		 2cmlC-6c0wA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 TRP A  86
ALA B  83
VAL B  81
 TRP  A  86 ( 0.5A)
ALA  B  83 ( 0.0A)
VAL  B  81 ( 0.6A)
 0.78A 2izqA-6c0wA:
undetectable
2izqB-6c0wA:
undetectable		 2izqA-6c0wA:
undetectable
2izqB-6c0wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens) 		5 / 10 PHE A 106
ARG B  36
ALA B  33
LEU B  37
ALA B  38
 PHE  A 106 ( 1.3A)
ARG  B  36 ( 0.6A)
ALA  B  33 ( 0.0A)
LEU  B  37 ( 0.6A)
ALA  B  38 ( 0.0A)
 1.30A 2wscB-6c0wA:
undetectable		 2wscB-6c0wA:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens) 		5 / 10 PHE A 106
ARG B  36
ALA B  33
LEU B  37
ALA B  38
 PHE  A 106 ( 1.3A)
ARG  B  36 ( 0.6A)
ALA  B  33 ( 0.0A)
LEU  B  37 ( 0.6A)
ALA  B  38 ( 0.0A)
 1.31A 2wseB-6c0wA:
undetectable		 2wseB-6c0wA:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens) 		5 / 9 PHE A 106
ARG B  36
ALA B  33
LEU B  37
ALA B  38
 PHE  A 106 ( 1.3A)
ARG  B  36 ( 0.6A)
ALA  B  33 ( 0.0A)
LEU  B  37 ( 0.6A)
ALA  B  38 ( 0.0A)
 1.32A 2wsfB-6c0wA:
undetectable		 2wsfB-6c0wA:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ALA B  83
VAL B  81
TRP A  86
 ALA  B  83 ( 0.0A)
VAL  B  81 ( 0.6A)
TRP  A  86 ( 0.5A)
 0.75A 3l8lA-6c0wB:
undetectable
3l8lB-6c0wB:
undetectable		 3l8lA-6c0wB:
undetectable
3l8lB-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ALA B  83
VAL B  81
TRP A  86
 ALA  B  83 ( 0.0A)
VAL  B  81 ( 0.6A)
TRP  A  86 ( 0.5A)
 0.73A 3l8lC-6c0wB:
undetectable
3l8lD-6c0wB:
undetectable		 3l8lC-6c0wB:
undetectable
3l8lD-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens) 		5 / 10 PHE A 106
ARG B  36
ALA B  33
LEU B  37
ALA B  38
 PHE  A 106 ( 1.3A)
ARG  B  36 ( 0.6A)
ALA  B  33 ( 0.0A)
LEU  B  37 ( 0.6A)
ALA  B  38 ( 0.0A)
 1.30A 3lw5B-6c0wA:
undetectable		 3lw5B-6c0wA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens) 		5 / 11 PHE A 106
ARG B  36
ALA B  33
LEU B  37
ALA B  38
 PHE  A 106 ( 1.3A)
ARG  B  36 ( 0.6A)
ALA  B  33 ( 0.0A)
LEU  B  37 ( 0.6A)
ALA  B  38 ( 0.0A)
 1.32A 3pcqB-6c0wA:
2.3		 3pcqB-6c0wA:
5.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 6c0w CENTROMERE PROTEIN N
(Homo
sapiens) 		4 / 6 PHE K 108
PHE K 104
ALA K 161
THR K 163
 PHE  K 108 ( 1.3A)
PHE  K 104 ( 1.3A)
ALA  K 161 ( 0.0A)
THR  K 163 ( 0.8A)
 1.16A 3t3sB-6c0wK:
undetectable		 3t3sB-6c0wK:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens) 		4 / 5 LEU A  61
ARG B  35
ARG B  36
ILE B  46
 LEU  A  61 ( 0.6A)
ARG  B  35 ( 0.6A)
ARG  B  36 ( 0.6A)
ILE  B  46 ( 0.7A)
 1.43A 3ticA-6c0wA:
undetectable		 3ticA-6c0wA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_2
(NEURAMINIDASE)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens) 		4 / 5 LEU A  61
ARG B  35
ARG B  36
ILE B  46
 LEU  A  61 ( 0.6A)
ARG  B  35 ( 0.6A)
ARG  B  36 ( 0.6A)
ILE  B  46 ( 0.7A)
 1.43A 3ticD-6c0wA:
undetectable		 3ticD-6c0wA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 6c0w CENTROMERE PROTEIN N
(Homo
sapiens) 		4 / 8 PHE K 104
ALA K 161
THR K 163
LEU K 175
 PHE  K 104 ( 1.3A)
ALA  K 161 ( 0.0A)
THR  K 163 ( 0.8A)
LEU  K 175 ( 0.5A)
 0.91A 4ejgB-6c0wK:
undetectable		 4ejgB-6c0wK:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 6c0w CENTROMERE PROTEIN N
(Homo
sapiens) 		4 / 6 PHE K 104
ALA K 161
THR K 163
LEU K 175
 PHE  K 104 ( 1.3A)
ALA  K 161 ( 0.0A)
THR  K 163 ( 0.8A)
LEU  K 175 ( 0.5A)
 0.89A 4ejgD-6c0wK:
undetectable		 4ejgD-6c0wK:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens) 		4 / 8 GLY B  48
LEU B  49
ILE B  50
THR A 120
 GLY  B  48 ( 0.0A)
LEU  B  49 ( 0.6A)
ILE  B  50 ( 0.7A)
THR  A 120 ( 0.8A)
 0.81A 4em2A-6c0wB:
undetectable		 4em2A-6c0wB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 6c0w CENTROMERE PROTEIN N
(Homo
sapiens) 		5 / 12 LEU K  36
THR K  22
VAL K  48
LEU K  52
ILE K  16
 LEU  K  36 ( 0.5A)
THR  K  22 ( 0.8A)
VAL  K  48 ( 0.6A)
LEU  K  52 ( 0.6A)
ILE  K  16 ( 0.7A)
 1.08A 4g1bA-6c0wK:
undetectable		 4g1bA-6c0wK:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 6c0w HISTONE H4
(Homo
sapiens) 		4 / 6 THR B  82
ALA B  83
VAL B  87
TYR B  88
 THR  B  82 ( 0.8A)
ALA  B  83 ( 0.0A)
VAL  B  87 ( 0.6A)
TYR  B  88 ( 1.3A)
 0.82A 5ecoA-6c0wB:
undetectable		 5ecoA-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 6c0w CENTROMERE PROTEIN N
(Homo
sapiens) 		3 / 3 SER K 156
TYR K 155
TYR K 154
 SER  K 156 ( 0.0A)
TYR  K 155 ( 1.3A)
TYR  K 154 ( 1.3A)
 0.76A 5lakA-6c0wK:
undetectable
5lakI-6c0wK:
undetectable		 5lakA-6c0wK:
undetectable
5lakI-6c0wK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 6c0w CENTROMERE PROTEIN N
(Homo
sapiens) 		3 / 3 SER K 156
TYR K 155
TYR K 154
 SER  K 156 ( 0.0A)
TYR  K 155 ( 1.3A)
TYR  K 154 ( 1.3A)
 0.73A 5lakC-6c0wK:
undetectable
5lakJ-6c0wK:
undetectable		 5lakC-6c0wK:
undetectable
5lakJ-6c0wK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.62A 5qgjA-6c0wB:
undetectable		 5qgjA-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.62A 5qgmA-6c0wB:
undetectable		 5qgmA-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.63A 5qgnA-6c0wB:
undetectable		 5qgnA-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.64A 5qgyA-6c0wB:
undetectable		 5qgyA-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.65A 5qgzA-6c0wB:
undetectable		 5qgzA-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.65A 5qh0A-6c0wB:
undetectable		 5qh0A-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.66A 5qh2A-6c0wB:
undetectable		 5qh2A-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.65A 5qh3A-6c0wB:
undetectable		 5qh3A-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.64A 5qh5A-6c0wB:
undetectable		 5qh5A-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.68A 5qh6A-6c0wB:
undetectable		 5qh6A-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.63A 5qh7A-6c0wB:
undetectable		 5qh7A-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.67A 5qhaA-6c0wB:
undetectable		 5qhaA-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL B  60
VAL B  57
GLN A 127
 VAL  B  60 ( 0.6A)
VAL  B  57 ( 0.6A)
GLN  A 127 ( 0.6A)
 0.65A 5qhhA-6c0wB:
undetectable		 5qhhA-6c0wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 6c0w HISTONE H3-LIKE
CENTROMERIC PROTEIN
A
HISTONE H4
(Homo
sapiens;
Homo
sapiens) 		5 / 12 TYR B  88
ASN B  64
ALA A  71
ALA A  98
PHE A  67
 TYR  B  88 ( 1.3A)
ASN  B  64 ( 0.6A)
ALA  A  71 ( 0.0A)
ALA  A  98 ( 0.0A)
PHE  A  67 ( 1.3A)
 1.05A 5zw4A-6c0wB:
undetectable		 5zw4A-6c0wB:
undetectable