SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c14'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)
6c14

(;
)
4 / 5 SER B  22
VAL A1400
VAL B  19
SER A1403
None
1.21A 2j9cA-6c14B:
undetectable
2j9cB-6c14B:
undetectable
2j9cC-6c14B:
undetectable
2j9cA-6c14B:
undetectable
2j9cB-6c14B:
undetectable
2j9cC-6c14B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)
6c14 -
(-)
4 / 6 TYR A1350
ILE A1359
ASN A1343
LEU A1339
None
1.35A 2wekB-6c14A:
undetectable
2wekB-6c14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)
6c14 -
(-)
4 / 6 ASP A1231
ALA A1185
TYR A1205
ASP A1175
None
1.18A 4mdaA-6c14A:
undetectable
4mdaA-6c14A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)
6c14 -
(-)
4 / 6 VAL A1289
LYS A1288
ALA A1287
VAL A1280
None
1.03A 5i8fA-6c14A:
undetectable
5i8fA-6c14A:
undetectable