SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		3 / 3 SER P 216
GLU P 217
GLU P 218
 None
 0.68A 1eqbD-6c1dP:
undetectable		 1eqbD-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		3 / 3 SER P 216
GLU P 217
GLU P 218
 None
 0.68A 1eqbB-6c1dP:
undetectable		 1eqbB-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		3 / 3 GLN P 615
TYR P  58
ARG P  59
 None
 0.87A 1gtbA-6c1dP:
undetectable		 1gtbA-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 12 GLY P 132
SER P 145
ILE P 368
GLY P 183
ILE P 372
 None
 1.12A 1q8jB-6c1dP:
3.5		 1q8jB-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 7 PHE P 251
PHE P 152
PHE P 208
LEU P 225
 None
 1.11A 1qcaA-6c1dP:
undetectable		 1qcaA-6c1dP:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 11 TYR P  78
VAL P  17
GLY P  16
LEU P  22
ARG P 691
 None
 1.26A 2bxgA-6c1dP:
2.5		 2bxgA-6c1dP:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 11 LEU P 211
LEU P 364
PHE P 361
TYR P 357
GLY P 153
 None
 0.97A 2bxmA-6c1dP:
undetectable		 2bxmA-6c1dP:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 12 GLU P 392
PHE P 394
LEU P 621
GLY P 108
SER P 110
 None
 1.10A 2e7fA-6c1dP:
2.8		 2e7fA-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 12 GLU P 392
PHE P 394
LEU P 621
GLY P 108
SER P 110
 None
 1.14A 2ogyB-6c1dP:
2.1		 2ogyB-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 10 ILE P 300
LEU P 538
LEU P 281
ILE P 284
PHE P 286
 None
 1.08A 2w9sD-6c1dP:
undetectable		 2w9sD-6c1dP:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 10 ILE P 300
LEU P 538
LEU P 281
ILE P 284
PHE P 286
 None
 1.08A 2w9sF-6c1dP:
undetectable		 2w9sF-6c1dP:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 12 THR P 587
VAL P 382
VAL P 385
GLY P 384
ASP P 171
 None
 1.16A 3bf1A-6c1dP:
0.8
3bf1B-6c1dP:
undetectable		 3bf1A-6c1dP:
undetectable
3bf1B-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 10 ILE P 550
PHE P 554
ILE P 315
VAL P 278
LEU P 352
 None
 1.25A 3eqmA-6c1dP:
undetectable		 3eqmA-6c1dP:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 8 ASP P 461
PHE P 475
CYH P 483
LEU P 448
 None
 0.96A 3m0wE-6c1dP:
undetectable
3m0wF-6c1dP:
undetectable
3m0wG-6c1dP:
undetectable
3m0wH-6c1dP:
0.6		 3m0wE-6c1dP:
19.82
3m0wF-6c1dP:
19.82
3m0wG-6c1dP:
19.82
3m0wH-6c1dP:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 8 LEU P 235
GLN P 198
TYR P 209
PHE P 208
 None
 1.35A 3po7A-6c1dP:
undetectable		 3po7A-6c1dP:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 8 GLY P 681
TYR P 632
GLN P 424
ARG P 688
 None
 1.04A 3s3mA-6c1dP:
undetectable		 3s3mA-6c1dP:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 12 ILE P 550
PHE P 554
ILE P 315
VAL P 278
LEU P 352
 None
 1.23A 3s79A-6c1dP:
undetectable		 3s79A-6c1dP:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 4 LEU P 189
ILE P 414
TYR P 169
TYR P 406
 None
 1.41A 3vt7A-6c1dP:
undetectable		 3vt7A-6c1dP:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 8 PHE P 166
SER P 186
MET P 170
VAL P 365
 None
 1.38A 4capA-6c1dP:
undetectable
4capB-6c1dP:
undetectable		 4capA-6c1dP:
11.33
4capB-6c1dP:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 12 GLU P 409
ASN P 405
PHE P 391
LEU P 479
ILE P 449
 None
 1.09A 4djeA-6c1dP:
undetectable		 4djeA-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		6 / 12 GLY P 113
GLY P 111
SER P 164
ALA P 117
CYH P 595
ILE P 593
 ADP  P 802 ( 3.2A)
ADP  P 802 ( 3.7A)
MG  P 801 ( 4.6A)
None
None
None
 1.28A 4krhB-6c1dP:
undetectable		 4krhB-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 7 ASN P 397
GLU P 395
GLU P 202
GLU P 392
 None
 1.27A 4mi4A-6c1dP:
undetectable
4mi4C-6c1dP:
undetectable		 4mi4A-6c1dP:
20.69
4mi4C-6c1dP:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 7 ASN P 397
GLU P 395
GLU P 202
GLU P 392
 None
 1.08A 4mj8C-6c1dP:
undetectable		 4mj8C-6c1dP:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 12 GLY P 631
ALA P 630
ILE P 687
ASN P 689
GLN P 636
 None
 1.29A 4rtpA-6c1dP:
undetectable		 4rtpA-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 6 GLU P 490
PHE P 489
PHE P 510
TYR P 521
 None
 1.35A 4uciA-6c1dP:
undetectable		 4uciA-6c1dP:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 7 GLU P 490
PHE P 489
PHE P 510
TYR P 521
 None
 1.36A 4uciB-6c1dP:
undetectable		 4uciB-6c1dP:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 10 PHE P 152
ALA P 151
VAL P 275
LEU P 223
PHE P 251
 None
 1.19A 4zmeB-6c1dP:
undetectable		 4zmeB-6c1dP:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		3 / 3 ASP P  89
ARG P  73
TYR P  92
 None
 0.80A 5a7mA-6c1dP:
undetectable		 5a7mA-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		3 / 3 ASP P  89
ARG P  73
TYR P  92
 None
 0.84A 5a7mB-6c1dP:
undetectable		 5a7mB-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 4 LEU P 460
ILE P 456
GLY P 571
ILE P 449
 None
 0.88A 5dzk3-6c1dP:
undetectable
5dzkm-6c1dP:
undetectable		 5dzk3-6c1dP:
undetectable
5dzkm-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		6 / 12 LEU P 352
ALA P 323
LEU P 320
ILE P 284
LYS P 303
ILE P 309
 None
 1.38A 5itzB-6c1dP:
undetectable		 5itzB-6c1dP:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 12 ILE P 550
PHE P 554
ILE P 315
VAL P 278
LEU P 352
 None
 1.22A 5jkvA-6c1dP:
undetectable		 5jkvA-6c1dP:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 10 ILE P 550
PHE P 554
ILE P 315
VAL P 278
LEU P 352
 None
 1.26A 5jl7A-6c1dP:
undetectable		 5jl7A-6c1dP:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		3 / 3 MET P 258
GLU P 269
ARG P 255
 None
 1.07A 5tjyA-6c1dP:
undetectable		 5tjyA-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		3 / 3 MET P 258
GLU P 269
ARG P 255
 None
 1.12A 5tjzA-6c1dP:
undetectable		 5tjzA-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 8 SER P 186
MET P 170
VAL P 365
PHE P 166
 None
 1.21A 5uo7A-6c1dP:
undetectable
5uo7B-6c1dP:
undetectable		 5uo7A-6c1dP:
11.81
5uo7B-6c1dP:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 5 LEU P 272
ALA P 276
LEU P 279
LEU P 312
 None
 0.60A 5vkqA-6c1dP:
undetectable
5vkqD-6c1dP:
undetectable		 5vkqA-6c1dP:
undetectable
5vkqD-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 5 LEU P 312
LEU P 272
ALA P 276
LEU P 279
 None
 0.66A 5vkqA-6c1dP:
undetectable
5vkqB-6c1dP:
undetectable		 5vkqA-6c1dP:
undetectable
5vkqB-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 5 LEU P 312
LEU P 272
ALA P 276
LEU P 279
 None
 0.65A 5vkqB-6c1dP:
undetectable
5vkqC-6c1dP:
undetectable		 5vkqB-6c1dP:
undetectable
5vkqC-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 5 LEU P 312
LEU P 272
ALA P 276
LEU P 279
 None
 0.71A 5vkqC-6c1dP:
undetectable
5vkqD-6c1dP:
undetectable		 5vkqC-6c1dP:
undetectable
5vkqD-6c1dP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 7 ASN P 187
ASP P 171
GLY P 183
ASN P 369
 None
 1.02A 5x7pA-6c1dP:
undetectable		 5x7pA-6c1dP:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		4 / 8 THR P 107
CYH P 407
TYR P 389
LEU P 386
 None
 1.44A 6cnjD-6c1dP:
2.5
6cnjE-6c1dP:
1.2		 6cnjD-6c1dP:
25.81
6cnjE-6c1dP:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 6c1d UNCONVENTIONAL
MYOSIN-IB
(Rattus
norvegicus) 		5 / 11 LEU P 460
ASP P 461
ILE P 449
PHE P 399
ILE P 403
 None
 1.05A 6gp2B-6c1dP:
undetectable		 6gp2B-6c1dP:
15.48