SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 12 LEU B 354
SER B 357
PHE B 361
LEU B 362
GLU B 285
 None
 1.13A 1kw0A-6c1qB:
undetectable		 1kw0A-6c1qB:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 12 LEU B 354
SER B 357
PHE B 361
LEU B 362
GLU B 285
 None
 1.20A 1mmkA-6c1qB:
undetectable		 1mmkA-6c1qB:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 11 LEU B 354
SER B 357
PHE B 361
LEU B 362
GLU B 285
 None
 1.17A 1mmtA-6c1qB:
undetectable		 1mmtA-6c1qB:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA8_0
(GRAMICIDIN A)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		4 / 4 GLY B 275
VAL B 262
TRP B 188
GLY B 192
 None
 1.21A 1ng8A-6c1qB:
undetectable		 1ng8A-6c1qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB8_0
(GRAMICIDIN A)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		4 / 4 GLY B 275
VAL B 262
TRP B 188
GLY B 192
 None
 1.21A 1ng8B-6c1qB:
undetectable		 1ng8B-6c1qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 12 SER B 369
ALA B 126
ILE B 182
LEU B 178
LEU B 175
 None
 0.96A 3adsB-6c1qB:
undetectable		 3adsB-6c1qB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		3 / 3 ARG B 284
ASP B 277
ASP B 281
 None
 0.86A 3jayA-6c1qB:
undetectable		 3jayA-6c1qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		3 / 3 ARG B 284
ASP B 277
ASP B 281
 None
 0.84A 3jb2A-6c1qB:
undetectable		 3jb2A-6c1qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		3 / 3 ARG B 284
ASP B 277
ASP B 281
 None
 0.87A 3jb3A-6c1qB:
undetectable		 3jb3A-6c1qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA B 152
LEU B 213
LEU B 212
ALA B 158
TYR B 386
 None
 1.05A 4lg1A-6c1qB:
undetectable		 4lg1A-6c1qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA B 152
LEU B 213
LEU B 212
ALA B 158
TYR B 386
 None
 1.07A 4lg1B-6c1qB:
undetectable		 4lg1B-6c1qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA B 152
LEU B 213
LEU B 212
ALA B 158
TYR B 386
 None
 1.14A 4lg1C-6c1qB:
undetectable		 4lg1C-6c1qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 12 LEU B 409
GLY B 390
ALA B 389
ILE B 385
VAL B 333
 None
 0.99A 4xdrA-6c1qB:
undetectable		 4xdrA-6c1qB:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 11 SER B 369
ALA B 126
ILE B 182
LEU B 178
LEU B 175
 None
 1.00A 4xumB-6c1qB:
undetectable		 4xumB-6c1qB:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		4 / 5 LEU B 409
TYR B 386
ALA B 165
ASN B 141
 None
 1.13A 4y03B-6c1qB:
2.3		 4y03B-6c1qB:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 10 ILE B 210
TRP B 240
ILE B 156
ALA B 239
ALA B 244
 9P2  B 501 (-4.3A)
None
None
None
None
 1.25A 5zjiB-6c1qB:
2.6		 5zjiB-6c1qB:
13.48