SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c26'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 3
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 ALA 3 282
VAL 3 284
TRP A 368
 None
 0.94A 1gmkA-6c263:
undetectable
1gmkB-6c263:
undetectable		 1gmkA-6c263:
undetectable
1gmkB-6c263:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 ALA 5  29
VAL 5  76
TRP 1 245
 None
 0.99A 1gmkC-6c265:
undetectable
1gmkD-6c265:
undetectable		 1gmkC-6c265:
undetectable
1gmkD-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT SWP1
(Saccharomyces
cerevisiae) 		4 / 7 ASP C 119
LEU C 123
ILE C 133
MET C  94
 None
 1.03A 1n13I-6c26C:
undetectable
1n13L-6c26C:
undetectable		 1n13I-6c26C:
25.33
1n13L-6c26C:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 6 PHE 1  81
ALA 1  83
TYR 1  66
ILE 1  51
 None
 1.04A 1oniH-6c261:
undetectable
1oniI-6c261:
undetectable		 1oniH-6c261:
undetectable
1oniI-6c261:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 4 ALA A 268
VAL A 272
ALA A 269
HIS A 266
 None
 0.86A 1q23A-6c26A:
undetectable		 1q23A-6c26A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 4 ALA A 268
VAL A 272
ALA A 269
HIS A 266
 None
 0.91A 1q23F-6c26A:
undetectable		 1q23F-6c26A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 4 ALA A 268
VAL A 272
ALA A 269
HIS A 266
 None
 0.93A 1q23K-6c26A:
undetectable		 1q23K-6c26A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 117
PRO A 477
ILE A  37
LEU A  33
 EGY  A 801 (-4.8A)
None
None
None
 1.10A 1ya4B-6c26A:
undetectable		 1ya4B-6c26A:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 5 VAL A 116
ASN A 113
VAL A  36
ILE A  42
 None
EGY  A 801 (-3.3A)
None
None
 1.08A 1z2bC-6c26A:
undetectable		 1z2bC-6c26A:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.95A 2eikC-6c265:
3.2
2eikJ-6c265:
undetectable		 2eikC-6c265:
undetectable
2eikJ-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.95A 2eimP-6c265:
3.3
2eimW-6c265:
undetectable		 2eimP-6c265:
undetectable
2eimW-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1 238
GLY 1 368
PRO 1 369
 None
 0.40A 2hreD-6c261:
undetectable		 2hreD-6c261:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTU_A_BCZA801_1
(NEURAMINIDASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 4 ARG A 159
ASP A 166
GLU A  45
ARG A 404
 None
 1.37A 2htuA-6c26A:
undetectable		 2htuA-6c26A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 6 TYR A 236
TYR A 239
TYR A 231
ILE A 226
 None
 1.39A 2pgzD-6c26A:
undetectable
2pgzE-6c26A:
undetectable		 2pgzD-6c26A:
19.72
2pgzE-6c26A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT SWP1
(Saccharomyces
cerevisiae) 		4 / 7 ILE C 133
MET C  94
ASP C 119
LEU C 123
 None
 1.06A 2qqcB-6c26C:
undetectable
2qqcC-6c26C:
undetectable		 2qqcB-6c26C:
23.08
2qqcC-6c26C:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT SWP1
(Saccharomyces
cerevisiae) 		4 / 7 ASP C 119
LEU C 123
ILE C 133
MET C  94
 None
 1.04A 2qqcA-6c26C:
undetectable
2qqcF-6c26C:
undetectable		 2qqcA-6c26C:
24.00
2qqcF-6c26C:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT SWP1
(Saccharomyces
cerevisiae) 		4 / 7 ASP C 119
LEU C 123
ILE C 133
MET C  94
 None
 1.05A 2qqcG-6c26C:
undetectable
2qqcJ-6c26C:
undetectable		 2qqcG-6c26C:
24.00
2qqcJ-6c26C:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT SWP1
(Saccharomyces
cerevisiae) 		4 / 7 ASP C 119
LEU C 123
ILE C 133
MET C  94
 None
 1.05A 2qqcI-6c26C:
undetectable
2qqcL-6c26C:
undetectable		 2qqcI-6c26C:
24.00
2qqcL-6c26C:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT SWP1
(Saccharomyces
cerevisiae) 		4 / 7 ASP C 119
LEU C 123
ILE C 133
MET C  94
 None
 1.03A 2qqdA-6c26C:
undetectable
2qqdE-6c26C:
undetectable		 2qqdA-6c26C:
22.37
2qqdE-6c26C:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 7 GLY 1 386
ALA 1 387
LEU 1 383
SER 1 445
 None
 0.88A 2wekB-6c261:
undetectable		 2wekB-6c261:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 8 THR A 470
SER A 466
TYR A 156
SER A  31
 None
 1.20A 2xz5C-6c26A:
undetectable
2xz5D-6c26A:
undetectable		 2xz5C-6c26A:
undetectable
2xz5D-6c26A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA512_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		5 / 10 MET A 267
ALA A 269
TYR A 243
HIS A 266
GLY A 271
 EGY  A 803 (-4.6A)
None
None
None
EGY  A 803 ( 4.4A)
 1.47A 2zm8A-6c26A:
undetectable		 2zm8A-6c26A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		5 / 8 MET A 267
ALA A 269
TYR A 243
HIS A 266
GLY A 271
 EGY  A 803 (-4.6A)
None
None
None
EGY  A 803 ( 4.4A)
 1.39A 2zm9A-6c26A:
undetectable		 2zm9A-6c26A:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.94A 3ag4P-6c265:
3.2
3ag4W-6c265:
undetectable		 3ag4P-6c265:
undetectable
3ag4W-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.93A 3asnC-6c265:
3.2
3asnJ-6c265:
undetectable		 3asnC-6c265:
undetectable
3asnJ-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.95A 3asnP-6c265:
3.2
3asnW-6c265:
undetectable		 3asnP-6c265:
undetectable
3asnW-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.95A 3asoP-6c265:
3.1
3asoW-6c265:
undetectable		 3asoP-6c265:
undetectable
3asoW-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		3 / 3 CYH A 196
PHE A 200
PHE A 181
 EGY  1 502 ( 3.7A)
None
None
 0.81A 3cr5X-6c26A:
undetectable		 3cr5X-6c26A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		5 / 10 ASP A 534
ILE A 523
GLY A 524
GLY A 525
VAL A 479
 None
 1.00A 3em4V-6c26A:
undetectable		 3em4V-6c26A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 6 HIS 1 226
LEU 1 156
LYS 1 260
ALA 1 262
 None
 1.24A 3gv1A-6c261:
undetectable
3gv1C-6c261:
undetectable		 3gv1A-6c261:
undetectable
3gv1C-6c261:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 6 LEU 1 156
LYS 1 260
ALA 1 262
HIS 1 226
 None
 1.21A 3gv1A-6c261:
undetectable
3gv1B-6c261:
undetectable		 3gv1A-6c261:
undetectable
3gv1B-6c261:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 5 LYS 1 275
SER 1 151
LEU 1 271
SER 1 269
 None
 1.18A 3ijxH-6c261:
undetectable		 3ijxH-6c261:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 4 LYS 1 275
SER 1 151
LEU 1 271
SER 1 269
 None
 1.06A 3ik6H-6c261:
undetectable		 3ik6H-6c261:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 5 LYS 1 275
SER 1 151
LEU 1 271
SER 1 269
 None
 1.12A 3iluH-6c261:
undetectable		 3iluH-6c261:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 527
ILE A 523
GLY A 524
LEU A 503
THR A 531
 None
 1.00A 3kw2A-6c26A:
undetectable		 3kw2A-6c26A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 527
ILE A 523
GLY A 524
LEU A 503
THR A 531
 None
 1.01A 3kw2B-6c26A:
undetectable		 3kw2B-6c26A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 255
GLY A 163
ALA A 119
ILE A 170
MET A  91
 None
 1.46A 3ld6B-6c26A:
undetectable		 3ld6B-6c26A:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 7 ILE 1  51
TYR 1  66
THR 1  68
ASN 1  33
 None
 0.93A 3p50A-6c261:
4.6		 3p50A-6c261:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 7 ILE 1  51
TYR 1  66
THR 1  68
ASN 1  33
 None
 0.93A 3p50B-6c261:
2.2		 3p50B-6c261:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 7 ILE 1  51
TYR 1  66
THR 1  68
ASN 1  33
 None
 0.92A 3p50C-6c261:
4.1		 3p50C-6c261:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 7 ILE 1  51
TYR 1  66
THR 1  68
ASN 1  33
 None
 0.94A 3p50D-6c261:
2.3		 3p50D-6c261:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 7 ILE 1  51
TYR 1  66
THR 1  68
ASN 1  33
 None
 0.92A 3p50E-6c261:
4.6		 3p50E-6c261:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 6 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.95A 3wg7C-6c265:
3.2
3wg7J-6c265:
undetectable		 3wg7C-6c265:
undetectable
3wg7J-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT SWP1
(Saccharomyces
cerevisiae) 		3 / 3 GLU C  99
TYR C 109
SER C 107
 None
 1.01A 4at0A-6c26C:
undetectable		 4at0A-6c26C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT SWP1
(Saccharomyces
cerevisiae) 		3 / 3 LYS C 147
LYS C 145
PRO C 146
 None
 1.08A 4dv1L-6c26C:
undetectable		 4dv1L-6c26C:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 216
ASP A 265
PHE A 398
LEU A 394
 None
None
None
EGY  3 401 ( 4.8A)
 1.05A 4f8hA-6c26A:
2.2
4f8hB-6c26A:
2.2		 4f8hA-6c26A:
13.65
4f8hB-6c26A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 216
ASP A 265
PHE A 398
LEU A 394
 None
None
None
EGY  3 401 ( 4.8A)
 1.05A 4f8hB-6c26A:
2.2
4f8hC-6c26A:
2.3		 4f8hB-6c26A:
13.65
4f8hC-6c26A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 216
ASP A 265
PHE A 398
LEU A 394
 None
None
None
EGY  3 401 ( 4.8A)
 1.04A 4f8hC-6c26A:
2.3
4f8hD-6c26A:
2.2		 4f8hC-6c26A:
13.65
4f8hD-6c26A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 216
ASP A 265
PHE A 398
LEU A 394
 None
None
None
EGY  3 401 ( 4.8A)
 1.06A 4f8hD-6c26A:
2.2
4f8hE-6c26A:
2.2		 4f8hD-6c26A:
13.65
4f8hE-6c26A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 170
LEU A 121
PHE A 118
TYR A 203
THR A 173
 None
EGY  A 801 ( 3.7A)
None
EGY  C 301 (-4.6A)
None
 1.41A 4i1nA-6c26A:
undetectable		 4i1nA-6c26A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 8 HIS A 266
PRO A 260
ALA A 269
TYR A 243
 None
 0.89A 4k0bB-6c26A:
undetectable		 4k0bB-6c26A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 3
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		3 / 3 GLU 3 269
TRP A 356
LYS 3 255
 None
 1.37A 4k7aA-6c263:
undetectable		 4k7aA-6c263:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 8 HIS A 266
PRO A 260
ALA A 269
TYR A 243
 None
 0.88A 4l7iB-6c26A:
undetectable		 4l7iB-6c26A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 253
TYR A 203
SER A 206
ALA A 169
ALA A 171
 EGY  C 301 ( 4.7A)
EGY  C 301 (-4.6A)
EGY  C 301 ( 3.9A)
None
None
 1.37A 4u14A-6c26A:
undetectable		 4u14A-6c26A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 8 PHE A 149
ALA A 142
LEU A 145
GLY A 148
 None
 1.01A 4xk8a-6c26A:
undetectable		 4xk8a-6c26A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.84A 5b1bP-6c265:
3.3
5b1bW-6c265:
undetectable		 5b1bP-6c265:
undetectable
5b1bW-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 570
THR A 531
GLY A 520
ILE A 523
GLY A  79
 None
 0.99A 5d4uC-6c26A:
undetectable		 5d4uC-6c26A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 570
THR A 531
GLY A 520
ILE A 523
GLY A  79
 None
 0.96A 5d4uD-6c26A:
undetectable		 5d4uD-6c26A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 362
SER A 158
TYR A 474
 None
 0.77A 5glmA-6c26A:
undetectable		 5glmA-6c26A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		3 / 3 TRP A 598
ILE A 602
SER A 552
 None
 0.98A 5gqbA-6c26A:
undetectable		 5gqbA-6c26A:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 389
VAL A 374
LEU A 377
VAL A 419
ILE A 137
 None
 0.93A 5mugA-6c26A:
undetectable		 5mugA-6c26A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 421
SER A 422
PHE A 425
ASP A 426
 None
 0.67A 5om3A-6c26A:
undetectable
5om3B-6c26A:
undetectable		 5om3A-6c26A:
19.10
5om3B-6c26A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.93A 5x1fP-6c265:
3.3
5x1fW-6c265:
undetectable		 5x1fP-6c265:
undetectable
5x1fW-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_F_BEZF201_0
(NS3 PROTEASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 5 ALA 1  69
SER 1 166
TYR 1 168
TYR 1  66
 None
 1.41A 5yodF-6c261:
undetectable		 5yodF-6c261:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.82A 5z85C-6c265:
3.2
5z85J-6c265:
undetectable		 5z85C-6c265:
undetectable
5z85J-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.84A 5zcoC-6c265:
3.2
5zcoJ-6c265:
undetectable		 5zcoC-6c265:
undetectable
5zcoJ-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.84A 5zcqC-6c265:
3.2
5zcqJ-6c265:
undetectable		 5zcqC-6c265:
undetectable
5zcqJ-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 LEU 5  73
PHE 5  28
PHE 5  77
PHE 1 447
 None
 0.84A 5zcqP-6c265:
3.2
5zcqW-6c265:
undetectable		 5zcqP-6c265:
undetectable
5zcqW-6c265:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		3 / 3 PRO 1 442
SER 1 444
SER 1 445
 None
 0.54A 6bpyA-6c261:
undetectable		 6bpyA-6c261:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		3 / 3 TRP 1  31
ILE 1 123
GLU 1 128
 None
 0.83A 6hcxA-6c261:
undetectable		 6hcxA-6c261:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
(Saccharomyces
cerevisiae) 		5 / 12 HIS 1 226
THR 1 258
ALA 1  45
GLY 1 331
ALA 1 261
 None
 1.25A 6hwdV-6c261:
undetectable
6hwdb-6c261:
undetectable		 6hwdV-6c261:
22.47
6hwdb-6c261:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT 1
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		5 / 12 PHE A  39
ASN A 113
TYR A  52
LEU 1 310
GLY 1 309
 None
EGY  A 801 (-3.3A)
None
None
None
 1.19A 6r2eE-6c26A:
undetectable		 6r2eE-6c26A:
undetectable