SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c2s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JGS_A_SALA256_1 (MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN MARR)	6c2s	TRANSCRIPTIONAL REGULATOR, MARR FAMILY (Rhodopseudomonas palustris)	4 / 7	VAL A 82 THR A 76 LEU A 75 ARG A 118	None	0.91A	1jgsA-6c2sA: 15.4	1jgsA-6c2sA: 22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J9D_A_ACTA1117_0 (HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059)	6c2s	TRANSCRIPTIONAL REGULATOR, MARR FAMILY (Rhodopseudomonas palustris)	3 / 3	ASP A 167 ARG A 169 ARG A 166	None	1.09A	2j9dA-6c2sA: undetectable 2j9dC-6c2sA: undetectable	2j9dA-6c2sA: undetectable 2j9dC-6c2sA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3Z_B_9PLB501_1 (CYTOCHROME P450 2E1)	6c2s	TRANSCRIPTIONAL REGULATOR, MARR FAMILY (Rhodopseudomonas palustris)	4 / 6	LEU A 145 ALA A 78 THR A 76 LEU A 115	None	0.99A	3t3zB-6c2sA: undetectable	3t3zB-6c2sA: 9.98