SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c5d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 6c5d LLAJI.R1
(Helicobacter
pylori) 		4 / 8 LEU A  92
LEU A 116
ASP A  89
ARG A 112
 None
 1.07A 2j2pA-6c5dA:
undetectable
2j2pB-6c5dA:
undetectable		 2j2pA-6c5dA:
15.21
2j2pB-6c5dA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 6c5d LLAJI.R1
(Helicobacter
pylori) 		4 / 6 ASP A   9
LEU A  13
ASP A  88
LEU A 108
 None
 1.20A 3bj8C-6c5dA:
undetectable
3bj8D-6c5dA:
undetectable		 3bj8C-6c5dA:
19.51
3bj8D-6c5dA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 6c5d LLAJI.R1
(Helicobacter
pylori) 		4 / 8 GLY A 118
LEU A 119
ILE A 120
ILE A  90
 None
 0.86A 4em2A-6c5dA:
undetectable		 4em2A-6c5dA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6c5d LLAJI.R1
(Helicobacter
pylori) 		5 / 12 ILE A  65
ALA A  71
ILE A   8
LEU A  91
ILE A  18
 None
 1.03A 4kjjA-6c5dA:
undetectable		 4kjjA-6c5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 6c5d LLAJI.R1
(Helicobacter
pylori) 		5 / 12 LEU A  55
LEU A  25
ARG A  60
LEU A  61
ILE A  53
 None
 1.11A 4x1fA-6c5dA:
undetectable		 4x1fA-6c5dA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 6c5d LLAJI.R1
(Helicobacter
pylori) 		5 / 12 LEU A  55
LEU A  25
ARG A  60
LEU A  61
ILE A  53
 None
 1.11A 4x1gA-6c5dA:
undetectable		 4x1gA-6c5dA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 6c5d LLAJI.R1
(Helicobacter
pylori) 		5 / 12 ILE A  12
ILE A  87
ILE A  69
VAL A  73
ASP A  89
 None
 0.99A 6emuB-6c5dA:
undetectable		 6emuB-6c5dA:
undetectable