SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c5v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 6c5v ANTIBODY FAB AMMO1
HEAVY CHAIN
(Homo
sapiens) 		4 / 4 ALA H  40
ARG H  38
GLN H  43
GLU H  46
 None
 0.95A 1lqtB-6c5vH:
undetectable		 1lqtB-6c5vH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 6c5v ANTIBODY FAB AMMO1
HEAVY CHAIN
(Homo
sapiens) 		4 / 4 ALA H  40
ARG H  38
GLN H  43
GLU H  46
 None
 0.99A 1lquB-6c5vH:
undetectable		 1lquB-6c5vH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 6c5v GLYCOPROTEIN 42
(Human
gammaherpesvirus
4) 		4 / 6 TYR C 117
TYR C 142
PHE C 129
LEU C 177
 None
 0.96A 2w98A-6c5vC:
undetectable
2w98B-6c5vC:
undetectable		 2w98A-6c5vC:
11.48
2w98B-6c5vC:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 6c5v ANTIBODY FAB AMMO1
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 THR H 116
GLU H 154
HIS H 206
 None
 0.77A 3g1uB-6c5vH:
undetectable		 3g1uB-6c5vH:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 6c5v ENVELOPE
GLYCOPROTEIN L
(Human
gammaherpesvirus
4) 		5 / 12 TYR B 115
PHE B 118
SER B  60
ILE B  90
LEU B 107
 None
 1.21A 3lcvB-6c5vB:
undetectable		 3lcvB-6c5vB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 6c5v GLYCOPROTEIN 42
(Human
gammaherpesvirus
4) 		5 / 12 LEU C 149
GLY C 143
VAL C 195
PRO C 202
GLY C 172
 None
 0.96A 5f9zA-6c5vC:
undetectable		 5f9zA-6c5vC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 6c5v GLYCOPROTEIN 42
(Human
gammaherpesvirus
4) 		4 / 5 PRO C 144
VAL C 164
GLY C 172
VAL C 184
 None
 1.04A 6ak3B-6c5vC:
undetectable		 6ak3B-6c5vC:
19.51