SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c5w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 6c5w CALCIUM UNIPORTER
(Metarhizium
acridum) 		3 / 3 ALA A 396
ARG A 400
LYS A 404
 None
 0.99A 3kp5B-6c5wA:
0.8		 3kp5B-6c5wA:
23.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6c5w NANOBODY
(Escherichia
coli) 		5 / 12 VAL C   2
MET C  34
VAL C  78
ALA C  97
TYR C 107
 None
 0.87A 3qxvB-6c5wC:
19.1		 3qxvB-6c5wC:
72.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1507_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6c5w CALCIUM UNIPORTER
(Metarhizium
acridum) 		3 / 3 ARG A 261
LYS A 101
ARG A 247
 None
 1.32A 3w1wA-6c5wA:
undetectable
3w1wB-6c5wA:
undetectable		 3w1wA-6c5wA:
undetectable
3w1wB-6c5wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6c5w CALCIUM UNIPORTER
(Metarhizium
acridum) 		5 / 12 PHE A 249
ILE A 253
LEU A 158
LEU A 114
LEU A 116
 None
 1.29A 4xumA-6c5wA:
undetectable		 4xumA-6c5wA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 6c5w CALCIUM UNIPORTER
(Metarhizium
acridum) 		5 / 11 LEU A 104
ALA A 243
ASP A 242
GLY A 214
ILE A 240
 None
 1.28A 5kr2B-6c5wA:
undetectable		 5kr2B-6c5wA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6c5w NANOBODY
(Escherichia
coli) 		3 / 3 TYR C  33
ARG C  71
THR C  57
 None
 0.70A 5z84J-6c5wC:
undetectable		 5z84J-6c5wC:
undetectable