SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c5x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 6c5x SUPPRESSOR OF
CYTOKINE SIGNALLING
1
(Xenopus
laevis) 		4 / 8 ARG D 104
HIS D  90
SER D 125
ALA D 114
 None
 0.91A 2rk8A-6c5xD:
undetectable		 2rk8A-6c5xD:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 6c5x SUPPRESSOR OF
CYTOKINE SIGNALLING
1
(Xenopus
laevis) 		4 / 8 GLY D  99
PHE D 209
PHE D 207
PHE D  79
 None
 0.73A 3ko0B-6c5xD:
undetectable
3ko0J-6c5xD:
undetectable		 3ko0B-6c5xD:
21.78
3ko0J-6c5xD:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 6c5x SUPPRESSOR OF
CYTOKINE SIGNALLING
1
(Xenopus
laevis) 		4 / 8 GLY D  99
PHE D 209
PHE D 207
PHE D  79
 None
 1.01A 3ko0D-6c5xD:
undetectable
3ko0E-6c5xD:
undetectable		 3ko0D-6c5xD:
21.78
3ko0E-6c5xD:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 6c5x SUPPRESSOR OF
CYTOKINE SIGNALLING
1
(Xenopus
laevis) 		4 / 8 PHE D  79
GLY D  99
PHE D 209
PHE D 207
 None
 0.89A 3ko0B-6c5xD:
undetectable
3ko0J-6c5xD:
undetectable		 3ko0B-6c5xD:
21.78
3ko0J-6c5xD:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 6c5x SUPPRESSOR OF
CYTOKINE SIGNALLING
1
(Xenopus
laevis) 		4 / 8 GLY D  99
PHE D 209
PHE D 207
PHE D  79
 None
 0.80A 3ko0K-6c5xD:
undetectable
3ko0S-6c5xD:
undetectable		 3ko0K-6c5xD:
21.78
3ko0S-6c5xD:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 6c5x SUPPRESSOR OF
CYTOKINE SIGNALLING
1
(Xenopus
laevis) 		4 / 7 GLY D  99
PHE D 209
PHE D 207
PHE D  79
 None
 1.00A 3ko0L-6c5xD:
undetectable
3ko0N-6c5xD:
undetectable		 3ko0L-6c5xD:
21.78
3ko0N-6c5xD:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 6c5x SUPPRESSOR OF
CYTOKINE SIGNALLING
1
(Xenopus
laevis) 		4 / 7 PHE D  79
GLY D  99
PHE D 209
PHE D 207
 None
 0.89A 3ko0K-6c5xD:
undetectable
3ko0S-6c5xD:
undetectable		 3ko0K-6c5xD:
21.78
3ko0S-6c5xD:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 6c5x SUPPRESSOR OF
CYTOKINE SIGNALLING
1
(Xenopus
laevis) 		4 / 7 PHE D  79
GLY D  99
PHE D 209
PHE D 207
 None
 0.91A 3ko0R-6c5xD:
undetectable
3ko0T-6c5xD:
undetectable		 3ko0R-6c5xD:
21.78
3ko0T-6c5xD:
21.78