SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c6y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 6c6y JC57-14 HEAVY CHAIN
(Macaca
mulatta) 		3 / 3 SER A  53
GLY A  54
ARG A  50
 None
 0.33A 1t9wA-6c6yA:
undetectable		 1t9wA-6c6yA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		4 / 5 LEU B 179
GLY B 128
PRO B 120
VAL B 132
 None
 0.83A 2aojA-6c6yB:
undetectable		 2aojA-6c6yB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 6c6y JC57-14 HEAVY CHAIN
(Macaca
mulatta) 		4 / 8 ASN A  76
GLN A  77
TRP A  34
LYS A  94
 None
 1.05A 2cmlC-6c6yA:
undetectable		 2cmlC-6c6yA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 PHE B 209
GLU B 122
SER B 121
VAL B 125
 None
 1.42A 3dqtA-6c6yB:
undetectable
3dqtB-6c6yB:
undetectable		 3dqtA-6c6yB:
15.11
3dqtB-6c6yB:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 SER B 121
VAL B 125
PHE B 209
GLU B 122
 None
 1.46A 3n5tA-6c6yB:
undetectable
3n5tB-6c6yB:
undetectable		 3n5tA-6c6yB:
15.11
3n5tB-6c6yB:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		3 / 3 LYS B  42
LYS B  39
PRO B  40
 None
SO4  B 301 (-4.0A)
None
 1.05A 4dv1L-6c6yB:
undetectable		 4dv1L-6c6yB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 PHE B 209
GLU B 122
SER B 121
VAL B 125
 None
 1.45A 4k5jA-6c6yB:
undetectable
4k5jB-6c6yB:
undetectable		 4k5jA-6c6yB:
15.11
4k5jB-6c6yB:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		3 / 3 ARG B 142
GLN B 166
GLU B 165
 None
 0.86A 4tvtA-6c6yB:
undetectable		 4tvtA-6c6yB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 PHE B 209
GLU B 122
SER B 121
VAL B 125
 None
 1.40A 5adlA-6c6yB:
undetectable
5adlB-6c6yB:
undetectable		 5adlA-6c6yB:
15.11
5adlB-6c6yB:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 LEU B 135
THR B 172
SER B 162
THR B 164
 None
 0.85A 5bojB-6c6yB:
undetectable		 5bojB-6c6yB:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 6c6y JC57-14 HEAVY CHAIN
(Macaca
mulatta) 		5 / 12 GLY A 174
SER A 172
VAL A 150
LEU A 178
PRO A 167
 None
 1.19A 5ergB-6c6yA:
undetectable		 5ergB-6c6yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 PHE B 209
GLU B 122
SER B 121
VAL B 125
 None
 1.40A 5fj3A-6c6yB:
undetectable
5fj3B-6c6yB:
undetectable		 5fj3A-6c6yB:
15.11
5fj3B-6c6yB:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 PHE B 209
GLU B 122
SER B 121
VAL B 125
 None
 1.44A 5vv7A-6c6yB:
undetectable
5vv7B-6c6yB:
undetectable		 5vv7A-6c6yB:
15.11
5vv7B-6c6yB:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 PHE B 209
GLU B 122
SER B 121
VAL B 125
 None
 1.40A 5vvnA-6c6yB:
undetectable
5vvnB-6c6yB:
undetectable		 5vvnA-6c6yB:
15.11
5vvnB-6c6yB:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 SER B 121
VAL B 125
PHE B 209
GLU B 122
 None
 1.40A 6av6A-6c6yB:
undetectable
6av6B-6c6yB:
undetectable		 6av6A-6c6yB:
20.65
6av6B-6c6yB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 PHE B 209
GLU B 122
SER B 121
VAL B 125
 None
 1.42A 6av6C-6c6yB:
undetectable
6av6D-6c6yB:
undetectable		 6av6C-6c6yB:
20.65
6av6D-6c6yB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6c6y JC57-14 LIGHT CHAIN
(Macaca
mulatta) 		4 / 7 SER B 121
VAL B 125
PHE B 209
GLU B 122
 None
 1.45A 6av7A-6c6yB:
undetectable
6av7B-6c6yB:
undetectable		 6av7A-6c6yB:
20.65
6av7B-6c6yB:
20.65