SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 11 ARG A 201
LEU A 175
GLU A 232
HIS A 238
GLY A 242
 None
None
SO4  A 504 (-4.8A)
None
None
 1.36A 1cmaA-6c7sA:
undetectable
1cmaB-6c7sA:
undetectable		 1cmaA-6c7sA:
undetectable
1cmaB-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 GLN A 287
HIS A 281
PRO A 283
 None
None
RFH  A 502 ( 4.2A)
 0.90A 1d8cA-6c7sA:
undetectable		 1d8cA-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 11 LEU A  30
PHE A 165
ALA A 263
VAL A 122
LEU A 147
 None
None
None
FAD  A 501 (-4.0A)
None
 1.25A 1hbpA-6c7sA:
undetectable		 1hbpA-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 GLY A 292
ASN A 298
ALA A 327
VAL A 330
LEU A 262
 None
 1.02A 1jg4A-6c7sA:
2.7		 1jg4A-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ALA A  80
VAL A  71
TRP A  82
 None
 0.93A 1jo3A-6c7sA:
undetectable		 1jo3A-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ALA A  80
VAL A  71
TRP A  82
 None
 0.93A 1jo3B-6c7sA:
undetectable		 1jo3B-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ALA A  80
VAL A  71
TRP A  82
 None
 0.95A 1jo4A-6c7sA:
undetectable		 1jo4A-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ALA A  80
VAL A  71
TRP A  82
 None
 0.95A 1jo4B-6c7sA:
undetectable		 1jo4B-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 GLY A 242
ALA A 241
VAL A 192
THR A 187
VAL A 191
 None
 0.90A 1k6cB-6c7sA:
undetectable		 1k6cB-6c7sA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ALA A  80
VAL A  71
TRP A  82
 None
 0.77A 1nrmA-6c7sA:
undetectable		 1nrmA-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ALA A  80
VAL A  71
TRP A  82
 None
 0.77A 1nrmB-6c7sA:
undetectable		 1nrmB-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ALA A  80
VAL A  71
TRP A  82
 None
 0.94A 1nruA-6c7sA:
undetectable		 1nruA-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ALA A  80
VAL A  71
TRP A  82
 None
 0.94A 1nruB-6c7sA:
undetectable		 1nruB-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ALA A  80
VAL A  71
TRP A  82
 None
 0.53A 1nt5A-6c7sA:
undetectable		 1nt5A-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ALA A  80
VAL A  71
TRP A  82
 None
 0.53A 1nt5B-6c7sA:
undetectable		 1nt5B-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 LEU A  22
GLY A 408
VAL A  52
MET A  53
HIS A 450
 None
 1.40A 1z95A-6c7sA:
undetectable		 1z95A-6c7sA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		4 / 6 ARG A 196
GLY A 203
PHE A 202
PRO A 217
 RFH  A 502 (-3.1A)
RFH  A 502 (-3.6A)
None
None
 1.33A 2m2oB-6c7sA:
undetectable		 2m2oB-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 ALA A  76
GLN A 287
PRO A 283
LEU A 331
LEU A 341
 None
None
RFH  A 502 ( 4.2A)
None
RFH  A 502 (-4.4A)
 1.24A 2nv4A-6c7sA:
undetectable		 2nv4A-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 ALA A  76
GLN A 287
PRO A 283
LEU A 331
LEU A 341
 None
None
RFH  A 502 ( 4.2A)
None
RFH  A 502 (-4.4A)
 1.38A 2nv4B-6c7sA:
undetectable		 2nv4B-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		4 / 4 VAL A 271
THR A 268
VAL A 163
GLY A 162
 None
 1.16A 2p2fB-6c7sA:
2.4		 2p2fB-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 HIS A 324
TYR A 266
LEU A 273
VAL A 157
LEU A 331
 None
 1.38A 2prgB-6c7sA:
undetectable		 2prgB-6c7sA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		4 / 6 TRP A 310
GLY A 408
GLY A 300
PHE A 469
 None
 0.97A 2qx6A-6c7sA:
undetectable
2qx6B-6c7sA:
undetectable		 2qx6A-6c7sA:
15.17
2qx6B-6c7sA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 SER A  42
ARG A  41
GLN A  98
 FAD  A 501 (-3.1A)
FAD  A 501 (-3.6A)
FAD  A 501 (-3.1A)
 0.82A 2xnrA-6c7sA:
undetectable		 2xnrA-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 VAL A 376
ASN A 298
TRP A 301
 None
 1.01A 2y00B-6c7sA:
undetectable		 2y00B-6c7sA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 LEU A  14
GLY A   8
GLY A  10
SER A 155
LEU A 147
 None
FAD  A 501 (-3.3A)
FAD  A 501 (-3.4A)
None
None
 1.23A 3dh0A-6c7sA:
3.4		 3dh0A-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 GLY A 242
ALA A 241
VAL A 192
THR A 187
VAL A 191
 None
 0.79A 3el5B-6c7sA:
undetectable		 3el5B-6c7sA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 GLY A 242
ALA A 241
VAL A 192
THR A 187
VAL A 191
 None
 0.86A 3gguA-6c7sA:
undetectable		 3gguA-6c7sA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 ALA A  76
MET A 338
LEU A 341
ARG A 196
HIS A 281
 None
RFH  A 502 ( 3.9A)
RFH  A 502 (-4.4A)
RFH  A 502 (-3.1A)
None
 1.27A 3olsB-6c7sA:
undetectable		 3olsB-6c7sA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 11 LEU A 161
ALA A 277
ASP A 276
GLY A   8
ILE A   6
 None
None
FAD  A 501 (-2.8A)
FAD  A 501 (-3.3A)
None
 1.06A 3spkA-6c7sA:
undetectable		 3spkA-6c7sA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 LEU A 161
ALA A 277
ASP A 276
GLY A   8
ILE A   6
 None
None
FAD  A 501 (-2.8A)
FAD  A 501 (-3.3A)
None
 1.06A 3spkB-6c7sA:
undetectable		 3spkB-6c7sA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ARG A 158
PHE A 165
PRO A 166
 None
 0.75A 3zoaB-6c7sA:
undetectable		 3zoaB-6c7sA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ILE A 394
MET A 405
ARG A 406
 None
 0.93A 4lnwA-6c7sA:
undetectable		 4lnwA-6c7sA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		3 / 3 ILE A 394
MET A 405
ARG A 406
 None
 0.93A 4lnxA-6c7sA:
undetectable		 4lnxA-6c7sA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 11 GLY A   9
GLY A  10
ILE A   6
GLY A 119
ILE A 116
 FAD  A 501 ( 4.7A)
FAD  A 501 (-3.4A)
None
None
None
 1.01A 4qoiA-6c7sA:
3.3
4qoiB-6c7sA:
undetectable		 4qoiA-6c7sA:
15.17
4qoiB-6c7sA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 11 ASN A 298
LEU A 299
LEU A 272
LEU A 303
LEU A 316
 None
 1.17A 4wg0F-6c7sA:
undetectable
4wg0G-6c7sA:
undetectable
4wg0H-6c7sA:
undetectable		 4wg0F-6c7sA:
undetectable
4wg0G-6c7sA:
undetectable
4wg0H-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 11 LEU A 316
LEU A 303
ASN A 298
LEU A 299
LEU A 272
 None
 1.16A 4wg0G-6c7sA:
undetectable
4wg0H-6c7sA:
undetectable
4wg0I-6c7sA:
undetectable		 4wg0G-6c7sA:
undetectable
4wg0H-6c7sA:
undetectable
4wg0I-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 11 LEU A 316
LEU A 303
ASN A 298
LEU A 299
LEU A 272
 None
 1.17A 4wg0I-6c7sA:
undetectable
4wg0J-6c7sA:
undetectable
4wg0K-6c7sA:
undetectable		 4wg0I-6c7sA:
undetectable
4wg0J-6c7sA:
undetectable
4wg0K-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		4 / 6 SER A 318
GLU A 322
GLY A 308
ARG A 427
 None
 0.79A 5cdpA-6c7sA:
2.8
5cdpB-6c7sA:
undetectable		 5cdpA-6c7sA:
13.35
5cdpB-6c7sA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 LEU A  58
LEU A 104
LEU A 105
GLY A  44
LEU A  94
 None
None
None
RFH  A 502 ( 4.7A)
None
 1.07A 5gtrA-6c7sA:
undetectable		 5gtrA-6c7sA:
15.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		6 / 12 ARG A  43
GLY A  44
PHE A  69
PHE A  74
GLY A 203
VAL A 205
 RFH  A 502 ( 3.6A)
RFH  A 502 ( 4.7A)
RFH  A 502 ( 4.8A)
RFH  A 502 (-3.4A)
RFH  A 502 (-3.6A)
None
 1.39A 5koxA-6c7sA:
68.4		 5koxA-6c7sA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		11 / 12 GLY A  44
PHE A  69
PHE A  74
ARG A 196
GLY A 203
VAL A 205
ILE A 215
PHE A 256
THR A 284
GLY A 285
GLY A 286
 RFH  A 502 ( 4.7A)
RFH  A 502 ( 4.8A)
RFH  A 502 (-3.4A)
RFH  A 502 (-3.1A)
RFH  A 502 (-3.6A)
None
RFH  A 502 (-3.7A)
RFH  A 502 (-4.4A)
RFH  A 502 (-4.0A)
RFH  A 502 (-3.4A)
FAD  A 501 ( 3.3A)
 0.43A 5koxA-6c7sA:
68.4		 5koxA-6c7sA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		9 / 12 PHE A  69
PHE A  74
ARG A 196
GLY A 203
VAL A 205
ILE A 215
PHE A 256
THR A 284
GLY A 285
 RFH  A 502 ( 4.8A)
RFH  A 502 (-3.4A)
RFH  A 502 (-3.1A)
RFH  A 502 (-3.6A)
None
RFH  A 502 (-3.7A)
RFH  A 502 (-4.4A)
RFH  A 502 (-4.0A)
RFH  A 502 (-3.4A)
 1.09A 5koxA-6c7sA:
68.4		 5koxA-6c7sA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 9 LEU A  30
ILE A   5
GLY A 149
LEU A 136
ALA A 134
 None
 0.62A 5o96A-6c7sA:
undetectable
5o96B-6c7sA:
2.0		 5o96A-6c7sA:
undetectable
5o96B-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 PHE A  75
ALA A  76
ALA A 263
ALA A 278
LEU A 291
 None
 1.21A 5tl8A-6c7sA:
undetectable		 5tl8A-6c7sA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 PRO A  11
ILE A  96
SER A  42
MET A  53
LEU A  59
 FAD  A 501 (-3.4A)
None
FAD  A 501 (-3.1A)
None
None
 1.12A 6b52A-6c7sA:
undetectable		 6b52A-6c7sA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		7 / 12 HIS A  46
PHE A  74
LEU A 176
ARG A 196
PHE A 256
THR A 284
GLY A 285
 None
RFH  A 502 (-3.4A)
FAD  A 501 ( 4.6A)
RFH  A 502 (-3.1A)
RFH  A 502 (-4.4A)
RFH  A 502 (-4.0A)
RFH  A 502 (-3.4A)
 0.73A 6brdA-6c7sA:
63.3		 6brdA-6c7sA:
74.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		6 / 12 HIS A  46
PHE A  74
LEU A 176
PHE A 256
THR A 284
GLY A 286
 None
RFH  A 502 (-3.4A)
FAD  A 501 ( 4.6A)
RFH  A 502 (-4.4A)
RFH  A 502 (-4.0A)
FAD  A 501 ( 3.3A)
 1.29A 6brdA-6c7sA:
63.3		 6brdA-6c7sA:
74.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 HIS A  46
VAL A  71
ARG A 351
THR A 284
GLY A 285
 None
None
None
RFH  A 502 (-4.0A)
RFH  A 502 (-3.4A)
 1.24A 6brdA-6c7sA:
63.3		 6brdA-6c7sA:
74.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		5 / 12 HIS A  46
ARG A 351
THR A 284
GLY A 285
GLY A 286
 None
None
RFH  A 502 (-4.0A)
RFH  A 502 (-3.4A)
FAD  A 501 ( 3.3A)
 1.16A 6brdB-6c7sA:
63.3		 6brdB-6c7sA:
74.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		8 / 12 HIS A  46
PHE A  74
ARG A 196
GLY A 203
PHE A 256
THR A 284
GLY A 285
GLY A 286
 None
RFH  A 502 (-3.4A)
RFH  A 502 (-3.1A)
RFH  A 502 (-3.6A)
RFH  A 502 (-4.4A)
RFH  A 502 (-4.0A)
RFH  A 502 (-3.4A)
FAD  A 501 ( 3.3A)
 0.50A 6brdB-6c7sA:
63.3		 6brdB-6c7sA:
74.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		7 / 12 HIS A  46
PHE A  74
ARG A 196
GLY A 203
PHE A 256
THR A 284
GLY A 286
 None
RFH  A 502 (-3.4A)
RFH  A 502 (-3.1A)
RFH  A 502 (-3.6A)
RFH  A 502 (-4.4A)
RFH  A 502 (-4.0A)
FAD  A 501 ( 3.3A)
 1.17A 6brdB-6c7sA:
63.3		 6brdB-6c7sA:
74.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		4 / 6 VAL A  93
LEU A 176
ARG A 201
PRO A 283
 None
FAD  A 501 ( 4.6A)
None
RFH  A 502 ( 4.2A)
 0.53A 6brdB-6c7sA:
63.3		 6brdB-6c7sA:
74.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		7 / 12 VAL A  71
ARG A 196
GLY A 203
PHE A 256
PRO A 283
THR A 284
GLY A 285
 None
RFH  A 502 (-3.1A)
RFH  A 502 (-3.6A)
RFH  A 502 (-4.4A)
RFH  A 502 ( 4.2A)
RFH  A 502 (-4.0A)
RFH  A 502 (-3.4A)
 0.90A 6brdC-6c7sA:
58.2		 6brdC-6c7sA:
74.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		6 / 12 VAL A  71
GLY A 203
PHE A 256
PRO A 283
THR A 284
GLY A 285
 None
RFH  A 502 (-3.6A)
RFH  A 502 (-4.4A)
RFH  A 502 ( 4.2A)
RFH  A 502 (-4.0A)
RFH  A 502 (-3.4A)
 1.23A 6brdC-6c7sA:
58.2		 6brdC-6c7sA:
74.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		6 / 12 VAL A  71
GLY A 203
PHE A 256
PRO A 283
THR A 284
GLY A 286
 None
RFH  A 502 (-3.6A)
RFH  A 502 (-4.4A)
RFH  A 502 ( 4.2A)
RFH  A 502 (-4.0A)
FAD  A 501 ( 3.3A)
 1.37A 6brdC-6c7sA:
58.2		 6brdC-6c7sA:
74.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		4 / 5 GLY A 292
LEU A 289
SER A  49
GLN A 294
 None
FAD  A 501 (-3.7A)
None
None
 1.29A 6ji6A-6c7sA:
undetectable		 6ji6A-6c7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 6c7s PUTATIVE RIFAMPIN
MONOOXYGENASE
(Nocardia
farcinica) 		4 / 7 HIS A 384
ARG A 389
HIS A 450
ASP A 385
 None
 1.20A 6mn4E-6c7sA:
undetectable		 6mn4E-6c7sA:
undetectable