SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 6c7v -
(-) 		5 / 10 PHE A  38
LEU A  47
PHE A  23
LEU A  10
HIS A 228
 None
 1.36A 1a8uA-6c7vA:
undetectable		 1a8uA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 6c7v -
(-) 		5 / 10 PHE A  38
LEU A  47
PHE A  23
LEU A  10
HIS A 228
 None
 1.34A 1a8uB-6c7vA:
undetectable		 1a8uB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6c7v -
(-) 		5 / 10 ARG A   5
ALA A 221
GLY A 217
ALA A 200
ILE A 187
 None
 1.03A 1gtnB-6c7vA:
undetectable
1gtnC-6c7vA:
undetectable		 1gtnB-6c7vA:
undetectable
1gtnC-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6c7v -
(-) 		5 / 10 ARG A   5
ALA A 221
GLY A 217
ALA A 200
ILE A 187
 None
 1.08A 1gtnH-6c7vA:
undetectable
1gtnI-6c7vA:
undetectable		 1gtnH-6c7vA:
undetectable
1gtnI-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 6c7v -
(-) 		3 / 3 ARG A 202
ILE A  11
TRP A  50
 None
 1.11A 1m8eB-6c7vA:
undetectable		 1m8eB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N6C_A_SAMA402_0
(SET
DOMAIN-CONTAINING
PROTEIN 7)		 6c7v -
(-) 		5 / 11 ILE A 113
ALA A 165
GLY A 166
GLU A 167
LYS A  99
 None
 1.27A 1n6cA-6c7vA:
undetectable		 1n6cA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 6c7v -
(-) 		3 / 3 ARG A 202
ILE A  11
TRP A  50
 None
 1.12A 1nodB-6c7vA:
undetectable		 1nodB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)		 6c7v -
(-) 		5 / 12 LEU A 241
HIS A 209
ILE A 232
PHE A 227
ILE A   6
 None
 1.44A 1ot7B-6c7vA:
undetectable		 1ot7B-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 6c7v -
(-) 		3 / 3 ARG A 202
ILE A  11
TRP A  50
 None
 1.19A 1qomA-6c7vA:
undetectable		 1qomA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 6c7v -
(-) 		4 / 6 ILE A 173
VAL A 125
ILE A  83
ILE A 116
 None
 0.82A 1uwhA-6c7vA:
undetectable		 1uwhA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.35A 1v54A-6c7vA:
undetectable
1v54C-6c7vA:
undetectable		 1v54A-6c7vA:
undetectable
1v54C-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.33A 1v54N-6c7vA:
undetectable
1v54P-6c7vA:
undetectable		 1v54N-6c7vA:
undetectable
1v54P-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.38A 1v55A-6c7vA:
undetectable
1v55C-6c7vA:
undetectable		 1v55A-6c7vA:
undetectable
1v55C-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 6c7v -
(-) 		4 / 4 GLY A  36
SER A  40
VAL A  69
LEU A  10
 None
 1.27A 1yajB-6c7vA:
undetectable		 1yajB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 6c7v -
(-) 		4 / 8 ALA A 131
THR A 149
ASN A 103
ILE A 129
 None
 0.81A 2dtjA-6c7vA:
undetectable
2dtjB-6c7vA:
undetectable		 2dtjA-6c7vA:
undetectable
2dtjB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 6c7v -
(-) 		5 / 9 ASN A 103
ILE A 129
GLY A 171
ALA A 131
THR A 149
 None
 1.31A 2dtjA-6c7vA:
undetectable
2dtjB-6c7vA:
undetectable		 2dtjA-6c7vA:
undetectable
2dtjB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.32A 2dyrA-6c7vA:
undetectable
2dyrC-6c7vA:
undetectable		 2dyrA-6c7vA:
undetectable
2dyrC-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.34A 2dyrN-6c7vA:
undetectable
2dyrP-6c7vA:
undetectable		 2dyrN-6c7vA:
undetectable
2dyrP-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.36A 2eijA-6c7vA:
undetectable
2eijC-6c7vA:
undetectable		 2eijA-6c7vA:
undetectable
2eijC-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.36A 2eijN-6c7vA:
undetectable
2eijP-6c7vA:
undetectable		 2eijN-6c7vA:
undetectable
2eijP-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.39A 2eikA-6c7vA:
undetectable
2eikC-6c7vA:
undetectable		 2eikA-6c7vA:
undetectable
2eikC-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.36A 2eilA-6c7vA:
undetectable
2eilC-6c7vA:
undetectable		 2eilA-6c7vA:
undetectable
2eilC-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 6c7v -
(-) 		4 / 8 SER A 172
LEU A 170
ASP A 183
ASP A 174
 None
 1.03A 2j2pA-6c7vA:
undetectable
2j2pB-6c7vA:
undetectable		 2j2pA-6c7vA:
undetectable
2j2pB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 6c7v -
(-) 		5 / 12 LEU A  65
MET A  62
LEU A  63
ILE A  83
GLY A  80
 None
 0.98A 2j7xA-6c7vA:
undetectable		 2j7xA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 6c7v -
(-) 		5 / 12 LEU A  65
MET A  62
LEU A  63
ILE A  83
GLY A  81
 None
 1.22A 2j7xA-6c7vA:
undetectable		 2j7xA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 6c7v -
(-) 		3 / 3 ARG A 202
ILE A  11
TRP A  50
 None
 1.11A 2nodB-6c7vA:
undetectable		 2nodB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 6c7v -
(-) 		5 / 10 PHE A 227
ALA A 223
ALA A 221
LEU A 241
VAL A 248
 None
 1.22A 2wuzA-6c7vA:
undetectable		 2wuzA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 6c7v -
(-) 		5 / 10 PHE A 227
ALA A 223
ALA A 221
LEU A 241
VAL A 248
 None
 1.18A 2wuzB-6c7vA:
undetectable		 2wuzB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.34A 2y69A-6c7vA:
undetectable
2y69C-6c7vA:
undetectable		 2y69A-6c7vA:
undetectable
2y69C-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 6c7v -
(-) 		5 / 12 LEU A  65
MET A  62
LEU A  63
ILE A  83
GLY A  81
 None
 1.21A 2yjaB-6c7vA:
undetectable		 2yjaB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.38A 3abkA-6c7vA:
undetectable
3abkC-6c7vA:
undetectable		 3abkA-6c7vA:
undetectable
3abkC-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.34A 3abkN-6c7vA:
undetectable
3abkP-6c7vA:
undetectable		 3abkN-6c7vA:
undetectable
3abkP-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.32A 3abmN-6c7vA:
undetectable
3abmP-6c7vA:
undetectable		 3abmN-6c7vA:
undetectable
3abmP-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.37A 3ag2A-6c7vA:
undetectable
3ag2C-6c7vA:
undetectable		 3ag2A-6c7vA:
undetectable
3ag2C-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.34A 3ag2N-6c7vA:
undetectable
3ag2P-6c7vA:
undetectable		 3ag2N-6c7vA:
undetectable
3ag2P-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.37A 3ag3A-6c7vA:
undetectable
3ag3C-6c7vA:
undetectable		 3ag3A-6c7vA:
undetectable
3ag3C-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.35A 3ag3N-6c7vA:
undetectable
3ag3P-6c7vA:
undetectable		 3ag3N-6c7vA:
undetectable
3ag3P-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.39A 3ag4A-6c7vA:
undetectable
3ag4C-6c7vA:
undetectable		 3ag4A-6c7vA:
undetectable
3ag4C-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.36A 3ag4N-6c7vA:
undetectable
3ag4P-6c7vA:
undetectable		 3ag4N-6c7vA:
undetectable
3ag4P-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6c7v -
(-) 		3 / 3 ARG A 202
ILE A  11
TRP A  50
 None
 1.06A 3e68A-6c7vA:
undetectable		 3e68A-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6c7v -
(-) 		3 / 3 ARG A 202
ILE A  11
TRP A  50
 None
 1.10A 3e6tB-6c7vA:
undetectable		 3e6tB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6c7v -
(-) 		3 / 3 ARG A 202
ILE A  11
TRP A  50
 None
 1.09A 3e7iB-6c7vA:
undetectable		 3e7iB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 6c7v -
(-) 		4 / 5 ASP A  85
ARG A  59
VAL A  79
THR A  53
 None
 1.20A 3eigA-6c7vA:
undetectable		 3eigA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6c7v -
(-) 		3 / 3 ARG A 202
ILE A  11
TRP A  50
 None
 1.14A 3nw2A-6c7vA:
undetectable		 3nw2A-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6c7v -
(-) 		3 / 3 ARG A 202
ILE A  11
TRP A  50
 None
 1.14A 3nw2B-6c7vA:
undetectable		 3nw2B-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6c7v -
(-) 		5 / 11 ILE A 113
ALA A 165
GLY A 166
GLU A 167
LYS A  99
 None
 1.27A 4e47A-6c7vA:
undetectable		 4e47A-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6c7v -
(-) 		5 / 11 ILE A 113
ALA A 165
GLY A 166
GLU A 167
LYS A  99
 None
 1.30A 4e47C-6c7vA:
undetectable		 4e47C-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 6c7v -
(-) 		5 / 12 LEU A  65
MET A  62
LEU A  63
ILE A  83
GLY A  80
 None
 0.89A 4j26A-6c7vA:
undetectable		 4j26A-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 6c7v -
(-) 		5 / 12 LEU A  65
MET A  62
LEU A  63
ILE A  83
GLY A  81
 None
 1.19A 4j26A-6c7vA:
undetectable		 4j26A-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6c7v -
(-) 		5 / 11 ILE A 113
ALA A 165
GLY A 166
GLU A 167
LYS A  99
 None
 1.30A 4jdsA-6c7vA:
undetectable		 4jdsA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6c7v -
(-) 		5 / 11 ILE A 113
ALA A 165
GLY A 166
GLU A 167
LYS A  99
 None
 1.32A 4jdsB-6c7vA:
undetectable		 4jdsB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6c7v -
(-) 		5 / 11 ILE A 113
ALA A 165
GLY A 166
GLU A 167
LYS A  99
 None
 1.29A 4jdsC-6c7vA:
undetectable		 4jdsC-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6c7v -
(-) 		4 / 7 GLU A 185
THR A 184
THR A 178
SER A 172
 None
 1.14A 4pfjA-6c7vA:
undetectable		 4pfjA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA907_0
(PROTEIN ARGONAUTE-2)		 6c7v -
(-) 		4 / 5 LYS A 146
THR A 104
THR A 142
TYR A 143
 None
 1.48A 4w5oA-6c7vA:
2.7		 4w5oA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 6c7v -
(-) 		4 / 6 LYS A 146
THR A 104
THR A 142
TYR A 143
 None
 1.44A 4w5rA-6c7vA:
undetectable		 4w5rA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 6c7v -
(-) 		4 / 6 LYS A 146
THR A 104
THR A 142
TYR A 143
 None
 1.48A 4w5tA-6c7vA:
undetectable		 4w5tA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 6c7v -
(-) 		4 / 6 LYS A 146
THR A 104
THR A 142
TYR A 143
 None
 1.47A 4z4cA-6c7vA:
undetectable		 4z4cA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 6c7v -
(-) 		4 / 5 LYS A 146
THR A 104
THR A 142
TYR A 143
 None
 1.49A 4z4dA-6c7vA:
3.2		 4z4dA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA907_0
(PROTEIN ARGONAUTE-2)		 6c7v -
(-) 		4 / 5 LYS A 146
THR A 104
THR A 142
TYR A 143
 None
 1.49A 4z4eA-6c7vA:
2.0		 4z4eA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6c7v -
(-) 		5 / 11 ILE A 113
ALA A 165
GLY A 166
GLU A 167
LYS A  99
 None
 1.27A 5ayfA-6c7vA:
undetectable		 5ayfA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.35A 5b1aN-6c7vA:
undetectable
5b1aP-6c7vA:
undetectable		 5b1aN-6c7vA:
undetectable
5b1aP-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.35A 5b1bN-6c7vA:
undetectable
5b1bP-6c7vA:
undetectable		 5b1bN-6c7vA:
undetectable
5b1bP-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.34A 5b3sN-6c7vA:
undetectable
5b3sP-6c7vA:
undetectable		 5b3sN-6c7vA:
undetectable
5b3sP-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 6c7v -
(-) 		5 / 11 LEU A  65
MET A  62
LEU A  63
ILE A  83
GLY A  81
 None
 1.18A 5dxbB-6c7vA:
undetectable		 5dxbB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6c7v -
(-) 		5 / 12 ARG A   5
ALA A 221
GLY A 217
ALA A 200
ILE A 187
 None
 1.01A 5eeuI-6c7vA:
undetectable
5eeuJ-6c7vA:
undetectable		 5eeuI-6c7vA:
undetectable
5eeuJ-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6c7v -
(-) 		5 / 12 ARG A   5
ALA A 221
GLY A 217
ALA A 200
ILE A 187
 None
 1.00A 5eevI-6c7vA:
undetectable
5eevJ-6c7vA:
undetectable		 5eevI-6c7vA:
undetectable
5eevJ-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6c7v -
(-) 		5 / 12 ARG A   5
ALA A 221
GLY A 217
ALA A 200
ILE A 187
 None
 1.01A 5eewI-6c7vA:
undetectable
5eewJ-6c7vA:
undetectable		 5eewI-6c7vA:
undetectable
5eewJ-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.35A 5iy5A-6c7vA:
undetectable
5iy5C-6c7vA:
undetectable		 5iy5A-6c7vA:
undetectable
5iy5C-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.36A 5x1fN-6c7vA:
undetectable
5x1fP-6c7vA:
undetectable		 5x1fN-6c7vA:
undetectable
5x1fP-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.36A 5zcqN-6c7vA:
undetectable
5zcqP-6c7vA:
undetectable		 5zcqN-6c7vA:
undetectable
5zcqP-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 6c7v -
(-) 		4 / 5 HIS A  84
GLU A  91
LEU A  65
VAL A  66
 None
 1.19A 6bc9A-6c7vA:
undetectable		 6bc9A-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.32A 6nmfN-6c7vA:
undetectable
6nmfP-6c7vA:
undetectable		 6nmfN-6c7vA:
undetectable
6nmfP-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c7v -
(-) 		4 / 7 TRP A  50
ASP A  98
THR A  78
HIS A 201
 None
 1.30A 6nmpN-6c7vA:
undetectable
6nmpP-6c7vA:
undetectable		 6nmpN-6c7vA:
undetectable
6nmpP-6c7vA:
undetectable