SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c80'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 11 ILE A 473
ASP A 393
LEU A 477
GLY A 478
PHE A 479
 None
 1.35A 1ju6A-6c80A:
undetectable		 1ju6A-6c80A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 10 ILE A 473
ASP A 393
LEU A 477
GLY A 478
PHE A 479
 None
 1.35A 1ju6C-6c80A:
undetectable		 1ju6C-6c80A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JUJ_A_LYAA315_1
(THYMIDYLATE SYNTHASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 10 ILE A 473
ASP A 393
LEU A 477
GLY A 478
PHE A 479
 None
 1.34A 1jujA-6c80A:
undetectable		 1jujA-6c80A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JUJ_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 10 ILE A 473
ASP A 393
LEU A 477
GLY A 478
PHE A 479
 None
 1.34A 1jujB-6c80A:
undetectable		 1jujB-6c80A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JUJ_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 10 ILE A 473
ASP A 393
LEU A 477
GLY A 478
PHE A 479
 None
 1.34A 1jujC-6c80A:
undetectable		 1jujC-6c80A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JUJ_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 10 ILE A 473
ASP A 393
LEU A 477
GLY A 478
PHE A 479
 None
 1.34A 1jujD-6c80A:
undetectable		 1jujD-6c80A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		3 / 3 ASP A 355
PHE A 361
ASN A 301
 None
 0.76A 1sg9B-6c80A:
undetectable		 1sg9B-6c80A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		4 / 4 ASP A 150
LEU A 170
LEU A 152
LEU A 147
 None
 1.35A 1u18A-6c80A:
undetectable		 1u18A-6c80A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		4 / 4 GLY A 229
SER A 179
VAL A 202
LEU A 516
 FAD  A 601 ( 3.7A)
FAD  A 601 (-3.4A)
None
None
 1.37A 1yajB-6c80A:
undetectable		 1yajB-6c80A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		4 / 6 LEU A 268
GLN A 271
LEU A 318
PHE A 261
 None
 1.11A 2einP-6c80A:
undetectable
2einW-6c80A:
undetectable		 2einP-6c80A:
undetectable
2einW-6c80A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 12 SER A  68
GLY A  59
GLY A 115
VAL A  85
ILE A  74
 None
 1.00A 2wa2B-6c80A:
undetectable		 2wa2B-6c80A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_A_TESA339_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 10 TYR A  53
THR A 235
SER A 143
ASN A 126
VAL A  82
 None
 1.42A 3burA-6c80A:
undetectable		 3burA-6c80A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_B_TESB340_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 10 TYR A  53
THR A 235
SER A 143
ASN A 126
VAL A  82
 None
 1.50A 3burB-6c80A:
undetectable		 3burB-6c80A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAS_A_ASDA332_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 10 TYR A  53
THR A 235
SER A 143
ASN A 126
VAL A  82
 None
 1.47A 3casA-6c80A:
undetectable		 3casA-6c80A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAS_B_ASDB331_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 9 TYR A  53
THR A 235
SER A 143
ASN A 126
VAL A  82
 None
 1.43A 3casB-6c80A:
0.0		 3casB-6c80A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 12 GLY A 101
GLY A 176
THR A 177
VAL A 117
GLY A 103
 FAD  A 601 (-3.5A)
FAD  A 601 (-3.5A)
FAD  A 601 ( 4.9A)
None
FAD  A 601 ( 3.9A)
 1.02A 3sglA-6c80A:
undetectable		 3sglA-6c80A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		4 / 7 PRO A 163
ARG A 164
GLY A 191
PRO A 192
 None
 1.25A 3ucbB-6c80A:
undetectable		 3ucbB-6c80A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		3 / 3 ASP A  61
TRP A 492
SER A  68
 None
 1.07A 4lrhA-6c80A:
undetectable		 4lrhA-6c80A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		4 / 7 GLN A 520
PRO A 518
ILE A 106
ASP A  61
 FAD  A 601 (-3.9A)
None
None
None
 1.06A 4pcuA-6c80A:
undetectable		 4pcuA-6c80A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		4 / 5 GLY A 101
ARG A 121
GLY A 145
GLU A 124
 FAD  A 601 (-3.5A)
None
None
None
 1.24A 4z2eB-6c80A:
undetectable
4z2eC-6c80A:
undetectable		 4z2eB-6c80A:
10.58
4z2eC-6c80A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 12 SER A  68
GLY A  59
GLY A 115
VAL A  85
ILE A  74
 None
 0.88A 5ec8A-6c80A:
undetectable		 5ec8A-6c80A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 6c80 CYTOKININ OXIDASE
LUCKX1.1
(Linum
usitatissimum) 		5 / 12 SER A  68
GLY A  59
GLY A 115
VAL A  85
ILE A  74
 None
 0.85A 5ekxA-6c80A:
undetectable		 5ekxA-6c80A:
undetectable