SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c96'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		4 / 6 LEU A 721
TYR A 361
THR A 383
LEU A 382
 None
 0.90A 1v54A-6c96A:
undetectable
1v54J-6c96A:
undetectable		 1v54A-6c96A:
undetectable
1v54J-6c96A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		4 / 6 LEU A 721
TYR A 361
THR A 383
LEU A 382
 None
 0.87A 2dyrA-6c96A:
3.9
2dyrJ-6c96A:
undetectable		 2dyrA-6c96A:
undetectable
2dyrJ-6c96A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		4 / 6 LEU A 721
TYR A 361
THR A 383
LEU A 382
 None
 0.93A 2dysA-6c96A:
3.8
2dysJ-6c96A:
undetectable		 2dysA-6c96A:
undetectable
2dysJ-6c96A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		4 / 6 LEU A 721
TYR A 361
THR A 383
LEU A 382
 None
 0.95A 2dysN-6c96A:
undetectable
2dysW-6c96A:
undetectable		 2dysN-6c96A:
undetectable
2dysW-6c96A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		4 / 6 LEU A 721
TYR A 361
THR A 383
LEU A 382
 None
 0.92A 2eijA-6c96A:
2.2
2eijJ-6c96A:
undetectable		 2eijA-6c96A:
undetectable
2eijJ-6c96A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		4 / 6 LEU A 721
TYR A 361
THR A 383
LEU A 382
 None
 0.88A 2eilA-6c96A:
undetectable
2eilJ-6c96A:
undetectable		 2eilA-6c96A:
undetectable
2eilJ-6c96A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		4 / 6 LEU A 721
TYR A 361
THR A 383
LEU A 382
 None
 0.94A 2zxwA-6c96A:
3.9
2zxwJ-6c96A:
undetectable		 2zxwA-6c96A:
undetectable
2zxwJ-6c96A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		4 / 6 LEU A 721
TYR A 361
THR A 383
LEU A 382
 None
 0.90A 3asnA-6c96A:
2.2
3asnJ-6c96A:
undetectable		 3asnA-6c96A:
undetectable
3asnJ-6c96A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		4 / 6 LEU A 721
TYR A 361
THR A 383
LEU A 382
 None
 0.90A 3asoA-6c96A:
1.7
3asoJ-6c96A:
1.2		 3asoA-6c96A:
undetectable
3asoJ-6c96A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		4 / 7 VAL A 320
ASP A 235
LEU A 316
ILE A 226
 None
 0.99A 3avpA-6c96A:
undetectable		 3avpA-6c96A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		5 / 12 PHE A 209
ALA A 148
VAL A 152
ILE A 584
THR A 577
 None
 1.15A 3czhB-6c96A:
undetectable		 3czhB-6c96A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		5 / 12 LEU A 277
PHE A 283
GLY A 251
LEU A 254
SER A 290
 None
 1.30A 3tbgC-6c96A:
undetectable		 3tbgC-6c96A:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		5 / 12 PHE A 669
THR A 661
PHE A 590
SER A 662
VAL A 272
 None
 1.45A 3u9fP-6c96A:
undetectable
3u9fS-6c96A:
undetectable		 3u9fP-6c96A:
undetectable
3u9fS-6c96A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		5 / 12 ILE A 710
GLY A 709
ALA A 408
SER A 770
TYR A 697
 None
 1.21A 5igvA-6c96A:
undetectable		 5igvA-6c96A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		3 / 3 GLY A 592
THR A 138
PRO A 129
 None
 0.64A 5v5zA-6c96A:
undetectable		 5v5zA-6c96A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		4 / 6 LEU A 721
TYR A 361
THR A 383
LEU A 382
 None
 0.91A 5x1fA-6c96A:
2.0
5x1fJ-6c96A:
undetectable		 5x1fA-6c96A:
undetectable
5x1fJ-6c96A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6c96 TWO PORE CALCIUM
CHANNEL PROTEIN 1
(Mus
musculus) 		4 / 7 LEU A 721
TYR A 361
THR A 383
LEU A 382
 None
 0.85A 6nmfA-6c96A:
2.2
6nmfJ-6c96A:
undetectable		 6nmfA-6c96A:
undetectable
6nmfJ-6c96A:
undetectable