SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6c9m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 ALA A 808
ASP A 811
GLU A 680
ARG A 714
GLU A 710
None
1.49A 1agmA-6c9mA:
4.1
1agmA-6c9mA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 ALA A 808
ASP A 811
GLU A 680
ARG A 714
GLU A 710
None
1.49A 1agmA-6c9mA:
4.1
1agmA-6c9mA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 11 GLU A 256
GLY B  85
LEU B  86
VAL A 325
PRO A 324
None
1.24A 1i9jH-6c9mA:
undetectable
1i9jL-6c9mA:
undetectable
1i9jH-6c9mA:
14.08
1i9jL-6c9mA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_0
(PROTEIN (METHIONINE
REPRESSOR))
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 9 LEU A  13
GLU A  10
HIS A  45
LEU A   6
PRO A   7
None
1.47A 1mj2A-6c9mA:
undetectable
1mj2A-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_0
(PROTEIN (METHIONINE
REPRESSOR))
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 9 LEU A  13
GLU A  10
HIS A  45
LEU A   6
PRO A   7
None
1.46A 1mj2C-6c9mA:
undetectable
1mj2C-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_0
(METHIONINE REPRESSOR)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 9 LEU A  13
GLU A  10
HIS A  45
LEU A   6
PRO A   7
None
1.47A 1mjoA-6c9mA:
undetectable
1mjoA-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_1
(METHIONINE REPRESSOR)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 9 LEU A  13
GLU A  10
HIS A  45
LEU A   6
PRO A   7
None
1.48A 1mjoB-6c9mA:
undetectable
1mjoB-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_0
(METHIONINE REPRESSOR)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 9 LEU A  13
GLU A  10
HIS A  45
LEU A   6
PRO A   7
None
1.48A 1mjoC-6c9mA:
undetectable
1mjoC-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 11 LEU A  13
GLU A  10
HIS A  45
LEU A   6
PRO A   7
None
1.43A 1mjqA-6c9mA:
undetectable
1mjqB-6c9mA:
undetectable
1mjqA-6c9mA:
undetectable
1mjqB-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 10 LEU A  13
GLU A  10
HIS A  45
LEU A   6
PRO A   7
None
1.44A 1mjqG-6c9mA:
undetectable
1mjqH-6c9mA:
undetectable
1mjqG-6c9mA:
undetectable
1mjqH-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 ASP A 363
LEU A 353
LEU A 358
None
0.79A 1np1B-6c9mA:
undetectable
1np1B-6c9mA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10

(Homo
sapiens)
3 / 3 ASP B  63
HIS B  69
ASP B  66
None
0.83A 1nw5A-6c9mB:
2.5
1nw5A-6c9mB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 ALA A 283
LEU A 264
LEU A 296
PRO A 297
LEU A 301
None
0.86A 1og5A-6c9mA:
undetectable
1og5A-6c9mA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 VAL A  69
ALA A  50
HIS A  45
None
0.63A 1q23G-6c9mA:
undetectable
1q23G-6c9mA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 VAL A  69
ALA A  50
HIS A  45
None
0.64A 1q23L-6c9mA:
undetectable
1q23L-6c9mA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
4 / 8 LYS A   1
SER A   5
PHE A  14
ASP A 110
None
1.15A 2bxkA-6c9mA:
2.4
2bxkA-6c9mA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 ALA A 808
ASP A 811
GLU A 680
ARG A 714
GLU A 710
None
1.40A 2f6dA-6c9mA:
2.3
2f6dA-6c9mA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 VAL A  81
TRP A 109
TRP A  83
None
0.99A 2xdcA-6c9mA:
undetectable
2xdcB-6c9mA:
undetectable
2xdcA-6c9mA:
undetectable
2xdcB-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 TRP A  83
VAL A  81
TRP A 109
None
0.97A 2xdcA-6c9mA:
undetectable
2xdcB-6c9mA:
undetectable
2xdcA-6c9mA:
undetectable
2xdcB-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 VAL A  81
TRP A  83
TRP A 109
None
1.29A 2xdcC-6c9mA:
undetectable
2xdcD-6c9mA:
undetectable
2xdcC-6c9mA:
undetectable
2xdcD-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 VAL A  81
TRP A 109
TRP A  83
None
0.81A 2xdcC-6c9mA:
undetectable
2xdcD-6c9mA:
undetectable
2xdcC-6c9mA:
undetectable
2xdcD-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 VAL A  81
TRP A 109
TRP A  83
None
0.97A 2y5mA-6c9mA:
undetectable
2y5mB-6c9mA:
undetectable
2y5mA-6c9mA:
undetectable
2y5mB-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 VAL A  81
TRP A 109
TRP A  83
None
0.97A 2y6nA-6c9mA:
undetectable
2y6nB-6c9mA:
undetectable
2y6nA-6c9mA:
undetectable
2y6nB-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 TRP A  83
VAL A  81
TRP A 109
None
0.95A 2y6nA-6c9mA:
undetectable
2y6nB-6c9mA:
undetectable
2y6nA-6c9mA:
undetectable
2y6nB-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 11 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
None
1.01A 3e22B-6c9mA:
undetectable
3e22B-6c9mA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 11 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
None
1.03A 3e22D-6c9mA:
undetectable
3e22D-6c9mA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 THR A 469
GLU A 481
HIS A 514
None
0.82A 3g1uB-6c9mA:
undetectable
3g1uB-6c9mA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 10 THR A 229
GLY A 231
GLU A 228
LEU A 233
LEU A 234
None
1.16A 3kvrA-6c9mA:
undetectable
3kvrA-6c9mA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 10 THR A 229
GLY A 231
GLU A 228
LEU A 233
LEU A 234
None
1.21A 3kvrB-6c9mA:
undetectable
3kvrB-6c9mA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10

(Homo
sapiens)
4 / 6 VAL B  53
VAL B  56
ILE B   3
ARG B  82
None
1.13A 3mssA-6c9mB:
undetectable
3mssA-6c9mB:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10

(Homo
sapiens)
4 / 6 VAL B  53
VAL B  56
ILE B   3
ARG B  82
None
1.14A 3mssC-6c9mB:
undetectable
3mssC-6c9mB:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 9 THR A 229
GLY A 231
GLU A 228
LEU A 233
LEU A 234
None
1.18A 3nbqA-6c9mA:
undetectable
3nbqA-6c9mA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10

(Homo
sapiens)
5 / 12 LEU B  75
GLU B  46
ALA B  45
MET B  14
LEU B  86
None
1.31A 3ou6D-6c9mB:
undetectable
3ou6D-6c9mB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
None
0.93A 3ut5B-6c9mA:
undetectable
3ut5B-6c9mA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
None
0.94A 3ut5D-6c9mA:
undetectable
3ut5D-6c9mA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 VAL A  81
TRP A  83
TRP A 109
None
1.16A 3zq8A-6c9mA:
undetectable
3zq8B-6c9mA:
undetectable
3zq8A-6c9mA:
undetectable
3zq8B-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 VAL A  81
TRP A 109
TRP A  83
None
0.88A 3zq8A-6c9mA:
undetectable
3zq8B-6c9mA:
undetectable
3zq8A-6c9mA:
undetectable
3zq8B-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_NCAA1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10

(Homo
sapiens)
4 / 7 THR B  73
HIS B 110
TYR B 137
TYR B  30
None
1.29A 4a3uA-6c9mB:
undetectable
4a3uA-6c9mB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_NCAB1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10

(Homo
sapiens)
4 / 7 THR B  73
HIS B 110
TYR B 137
TYR B  30
None
1.32A 4a3uB-6c9mB:
undetectable
4a3uB-6c9mB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
4 / 5 THR A 489
ILE A 511
GLU A 510
PHE A 660
None
1.48A 4ac9C-6c9mA:
undetectable
4ac9C-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 GLN A 251
ASN A 257
LEU A 264
ILE A 279
LEU A 277
None
1.34A 4k36A-6c9mA:
undetectable
4k36A-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
4 / 8 ASN B  13
GLU B   9
TYR B  31
TYR A 538
None
1.23A 4mj8A-6c9mB:
13.6
4mj8C-6c9mB:
13.8
4mj8A-6c9mB:
20.57
4mj8C-6c9mB:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
None
0.90A 4o2bB-6c9mA:
undetectable
4o2bB-6c9mA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
4 / 7 ASP A 546
PRO A 663
THR A 519
ASP A 520
None
0.92A 4pcuA-6c9mA:
undetectable
4pcuA-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB203_1
(CALMODULIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
4 / 7 PHE A 443
LEU B  20
ALA A 449
MET A 431
None
0.92A 4rjdB-6c9mA:
undetectable
4rjdB-6c9mA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
4 / 6 ILE A 125
GLN A 126
ILE A 100
ASP A  97
None
1.15A 4w5qA-6c9mA:
undetectable
4w5qA-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
4 / 6 ILE A 125
GLN A 126
ILE A 100
ASP A  97
None
1.02A 4w5tA-6c9mA:
undetectable
4w5tA-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
None
1.01A 4x1iD-6c9mA:
undetectable
4x1iD-6c9mA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
None
0.96A 4x1yB-6c9mA:
undetectable
4x1yB-6c9mA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
None
0.99A 4x1yD-6c9mA:
undetectable
4x1yD-6c9mA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 11 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
None
0.99A 4x20D-6c9mA:
undetectable
4x20D-6c9mA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
4 / 6 ILE A 125
GLN A 126
ILE A 100
ASP A  97
None
1.10A 4z4cA-6c9mA:
undetectable
4z4cA-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
None
1.03A 5itzB-6c9mA:
undetectable
5itzB-6c9mA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
3 / 3 CYH A 828
LYS A 830
HIS A 829
None
1.27A 5js5A-6c9mA:
undetectable
5js5A-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 9 ASP A 441
LEU B  22
PHE A 468
SER B 114
ASN B 115
None
1.38A 5l1fB-6c9mA:
0.1
5l1fB-6c9mA:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 12 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
None
0.92A 5mioB-6c9mA:
undetectable
5mioB-6c9mA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
4 / 8 GLY A  87
ARG A  70
TRP A  83
ASP A  93
None
0.96A 5vlmB-6c9mA:
3.6
5vlmB-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10

(Homo
sapiens)
3 / 3 TYR B 138
HIS B 110
MET B 147
None
1.26A 6af6A-6c9mB:
undetectable
6af6A-6c9mB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
4 / 6 ILE A 125
GLN A 126
ILE A 100
ASP A  97
None
1.11A 6cbdA-6c9mA:
undetectable
6cbdA-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT
N-ALPHA-ACETYLTRANSF
ERASE 10

(Homo
sapiens;
Homo
sapiens)
5 / 12 SER A 121
PHE A 523
ASP A 524
ILE A 125
LYS B  29
None
1.39A 6dwnB-6c9mA:
undetectable
6dwnB-6c9mA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10

(Homo
sapiens)
4 / 8 GLN B  88
SER B  95
PHE B 128
TYR B 122
None
1.15A 6eqpA-6c9mB:
undetectable
6eqpA-6c9mB:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 11 ASP A  93
SER A  92
TYR A  66
VAL A  69
SER A  79
None
1.40A 6hu9A-6c9mA:
1.1
6hu9E-6c9mA:
3.3
6hu9I-6c9mA:
undetectable
6hu9A-6c9mA:
undetectable
6hu9E-6c9mA:
undetectable
6hu9I-6c9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo
sapiens)
5 / 10 ASP A  93
SER A  92
TYR A  66
VAL A  69
SER A  79
None
1.39A 6hu9L-6c9mA:
undetectable
6hu9P-6c9mA:
undetectable
6hu9T-6c9mA:
undetectable
6hu9L-6c9mA:
undetectable
6hu9P-6c9mA:
undetectable
6hu9T-6c9mA:
undetectable