SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ca6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_B_DVAB8_0 (GRAMICIDIN A)	6ca6	PCT64_35S HEAVY CHAIN (Homo sapiens)	4 / 5	VAL H 23 GLY H 24 VAL H 5 TRP H 103	None	1.26A	1tkqB-6ca6H: undetectable	1tkqB-6ca6H: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WOP_A_FFOA2887_1 (AMINOMETHYLTRANSFERA SE)	6ca6	PCT64_35S HEAVY CHAIN (Homo sapiens)	3 / 3	ASP H 101 GLU H 6 ARG H 71	None	0.79A	1wopA-6ca6H: undetectable	1wopA-6ca6H: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA200_0 (ILEAL BILE ACID-BINDING PROTEIN)	6ca6	PCT64_35S HEAVY CHAIN (Homo sapiens)	4 / 5	PRO H 167 THR H 108 VAL H 89 GLY H 88	None	1.09A	3elzA-6ca6H: undetectable	3elzA-6ca6H: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA501_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	6ca6	PCT64_35S HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 90 LEU H 80 LEU H 82 ARG H 66	None	1.23A	4em2A-6ca6H: undetectable	4em2A-6ca6H: 18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BPY_A_ACTA408_0 (THIOREDOXIN REDUCTASE)	6ca6	PCT64_35S HEAVY CHAIN (Homo sapiens)	3 / 3	PRO H 185 SER H 187 SER H 188	None	0.25A	6bpyA-6ca6H: undetectable	6bpyA-6ca6H: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TKQ_B_DVAB8_0","GRAMICIDIN A","6ca6","PCT64_35S HEAVY CHAIN","Homo sapiens",4,"VAL H  23;GLY H  24;VAL H   5;TRP H 103","None","1.26A","1tkqB-6ca6H:undetectable","1tkqB-6ca6H:undetectable"],["1WOP_A_FFOA2887_1","AMINOMETHYLTRANSFERASE","6ca6","PCT64_35S HEAVY CHAIN","Homo sapiens",3,"ASP H 101;GLU H   6;ARG H  71","None","0.79A","1wopA-6ca6H:undetectable","1wopA-6ca6H:undetectable"],["3ELZ_A_CHDA200_0","ILEAL BILE ACID-BINDING PROTEIN","6ca6","PCT64_35S HEAVY CHAIN","Homo sapiens",4,"PRO H 167;THR H 108;VAL H  89;GLY H  88","None","1.09A","3elzA-6ca6H:undetectable","3elzA-6ca6H:undetectable"],["4EM2_A_SALA501_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","6ca6","PCT64_35S HEAVY CHAIN","Homo sapiens",4,"TYR H  90;LEU H  80;LEU H  82;ARG H  66","None","1.23A","4em2A-6ca6H:undetectable","4em2A-6ca6H:18.06"],["6BPY_A_ACTA408_0","THIOREDOXIN REDUCTASE","6ca6","PCT64_35S HEAVY CHAIN","Homo sapiens",3,"PRO H 185;SER H 187;SER H 188","None","0.25A","6bpyA-6ca6H:undetectable","6bpyA-6ca6H:undetectable"]]