SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cao'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6cao -
(-) 		6 / 12 ALA K  65
ALA K  64
GLN K  62
ASN K  27
LEU K  98
ALA K  97
 None
None
None
C  A 689 ( 3.4A)
None
None
 1.23A 2aclG-6caoK:
undetectable		 2aclG-6caoK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 6cao -
(-) 		5 / 12 GLY K  76
GLY K 102
ALA K  68
ALA K  65
ASP K  67
 None
 1.10A 3keeA-6caoK:
undetectable		 3keeA-6caoK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 6cao -
(-) 		5 / 11 TYR K  59
GLY K  90
ALA K  89
ALA K  65
GLN K  62
 None
 1.15A 3nmuB-6caoK:
4.2
3nmuJ-6caoK:
undetectable		 3nmuB-6caoK:
14.40
3nmuJ-6caoK:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 6cao -
(-) 		5 / 12 TYR K  59
GLY K  90
ALA K  89
ALA K  65
GLN K  62
 None
 1.22A 3nvkF-6caoK:
3.7
3nvkJ-6caoK:
undetectable		 3nvkF-6caoK:
14.67
3nvkJ-6caoK:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 6cao -
(-) 		4 / 4 ALA K  65
ALA K  68
ALA K  69
ALA K  72
 None
 0.12A 4oadA-6caoK:
undetectable		 4oadA-6caoK:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 6cao -
(-) 		4 / 4 ALA K  65
ALA K  68
ALA K  69
ALA K  72
 None
 0.09A 4oaeA-6caoK:
undetectable		 4oaeA-6caoK:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 6cao -
(-) 		4 / 5 GLY K  88
ARG K  91
GLY K  90
GLU K  92
 None
 1.15A 4z2eB-6caoK:
undetectable
4z2eC-6caoK:
undetectable		 4z2eB-6caoK:
undetectable
4z2eC-6caoK:
undetectable