SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cay'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 6cay STEROL-BINDING
PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 THR A 921
THR A 909
GLU A 890
LEU A 924
LEU A 912
 ERG  A1101 ( 4.5A)
None
None
None
ERG  A1101 ( 4.5A)
 1.47A 3gwxB-6cayA:
undetectable		 3gwxB-6cayA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 6cay STEROL-BINDING
PROTEIN
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 962
VAL A 868
TYR A 937
ARG A 881
 None
 1.08A 4r7iA-6cayA:
undetectable		 4r7iA-6cayA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 6cay STEROL-BINDING
PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 960
TYR A 976
GLU A 930
 None
 0.85A 5zmqD-6cayA:
undetectable
5zmqE-6cayA:
undetectable		 5zmqD-6cayA:
undetectable
5zmqE-6cayA:
undetectable