SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cbo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_2
(GLUCOAMYLASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		4 / 4 TRP A 415
GLU A 412
TRP A 391
LEU A 397
 None
 1.19A 1lf9A-6cboA:
0.0		 1lf9A-6cboA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 12 PHE A 258
LEU A 234
VAL A 230
ALA A 109
ALA A 110
 None
 1.33A 1q23A-6cboA:
undetectable
1q23B-6cboA:
undetectable		 1q23A-6cboA:
16.74
1q23B-6cboA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 12 PHE A 301
PHE A  47
ALA A 333
ALA A 334
HIS A 331
 None
 1.34A 1q23A-6cboA:
undetectable
1q23B-6cboA:
undetectable		 1q23A-6cboA:
16.74
1q23B-6cboA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 12 GLY A 244
GLY A 102
ILE A 229
ALA A 110
GLN A  93
 None
 1.10A 1ri4A-6cboA:
undetectable		 1ri4A-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 10 ILE A  45
ALA A  34
PHE A 353
ALA A 352
ILE A 365
 None
 0.91A 2aclC-6cboA:
undetectable		 2aclC-6cboA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 ILE A  45
ALA A  34
PHE A 353
ALA A 352
ILE A 365
 None
 1.06A 2aclE-6cboA:
undetectable		 2aclE-6cboA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 THR A 273
ALA A 352
ALA A 235
GLY A 237
ASP A  46
 None
 1.08A 2f16H-6cboA:
undetectable
2f16I-6cboA:
undetectable		 2f16H-6cboA:
14.55
2f16I-6cboA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 THR A 273
ALA A 352
ALA A 235
GLY A 237
ASP A  46
 None
 1.07A 2f16V-6cboA:
undetectable
2f16W-6cboA:
undetectable		 2f16V-6cboA:
14.55
2f16W-6cboA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 12 PHE A 301
ALA A 311
ALA A 388
GLY A 344
GLY A 392
 None
 0.87A 2igtA-6cboA:
4.3		 2igtA-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 12 PHE A 301
ALA A 311
ALA A 388
GLY A 344
GLY A 392
 None
 0.87A 2igtB-6cboA:
4.0		 2igtB-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		4 / 8 ALA A 300
ALA A 299
ILE A 365
HIS A 331
 None
 0.82A 3dtuC-6cboA:
undetectable
3dtuD-6cboA:
undetectable		 3dtuC-6cboA:
undetectable
3dtuD-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 10 ILE A  45
ALA A  34
PHE A 353
ALA A 352
ILE A 365
 None
 0.98A 3falA-6cboA:
undetectable		 3falA-6cboA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 ILE A  45
ALA A  34
PHE A 353
ALA A 352
ILE A 365
 None
 0.90A 3fc6A-6cboA:
undetectable		 3fc6A-6cboA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 10 VAL A 243
VAL A 227
GLY A 244
VAL A 100
GLY A  98
 None
 1.26A 3ls4H-6cboA:
undetectable		 3ls4H-6cboA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 THR A 273
ALA A 352
ALA A 235
GLY A 237
ASP A  46
 None
 1.10A 3mg0V-6cboA:
undetectable
3mg0W-6cboA:
undetectable		 3mg0V-6cboA:
14.55
3mg0W-6cboA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TX2_A_BEZA251_0
(PROBABLE
6-PHOSPHOGLUCONOLACT
ONASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		4 / 7 ALA A 398
TRP A 188
MET A 394
ALA A 390
 None
 1.08A 3tx2A-6cboA:
3.0		 3tx2A-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		4 / 6 PHE A 376
ARG A 379
LEU A 372
PRO A 307
 None
 1.30A 3vlnA-6cboA:
undetectable		 3vlnA-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		4 / 5 ILE A 177
VAL A 210
LEU A 316
ASP A 180
 None
 1.24A 3wzdA-6cboA:
undetectable		 3wzdA-6cboA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		4 / 8 TRP A 391
LEU A 414
ARG A 413
GLU A 384
 None
 1.22A 3zmdA-6cboA:
undetectable
3zmdB-6cboA:
undetectable		 3zmdA-6cboA:
20.79
3zmdB-6cboA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 ALA A 393
ASP A 180
PHE A 157
PHE A 155
ARG A 402
 None
 1.31A 4eilA-6cboA:
undetectable		 4eilA-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 10 ALA A 393
ASP A 180
PHE A 157
PHE A 155
ARG A 402
 None
 1.40A 4eilB-6cboA:
undetectable		 4eilB-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 ALA A 393
ASP A 180
PHE A 157
PHE A 155
ARG A 402
 None
 1.32A 4eilC-6cboA:
2.3		 4eilC-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 10 ALA A 393
ASP A 180
PHE A 157
PHE A 155
ARG A 402
 None
 1.34A 4eilD-6cboA:
undetectable		 4eilD-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 ALA A 393
ASP A 180
PHE A 157
PHE A 155
ARG A 402
 None
 1.39A 4eilE-6cboA:
2.2		 4eilE-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_F_FOLF703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 9 ALA A 393
ASP A 180
PHE A 157
PHE A 155
ARG A 402
 None
 1.36A 4eilF-6cboA:
undetectable		 4eilF-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 10 ALA A 393
ASP A 180
PHE A 157
PHE A 155
ARG A 402
 None
 1.38A 4eilG-6cboA:
undetectable		 4eilG-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_H_FOLH703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 9 ALA A 393
ASP A 180
PHE A 157
PHE A 155
ARG A 402
 None
 1.33A 4eilH-6cboA:
undetectable		 4eilH-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 10 ALA A 216
LEU A 212
VAL A 230
ALA A 270
THR A 273
 None
 1.04A 4j14A-6cboA:
undetectable		 4j14A-6cboA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 12 ALA A 393
ASP A 180
PHE A 157
PHE A 155
ARG A 402
 None
 1.32A 4kyaB-6cboA:
undetectable		 4kyaB-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 12 ALA A 393
ASP A 180
PHE A 157
PHE A 155
ARG A 402
 None
 1.33A 4kyaD-6cboA:
undetectable		 4kyaD-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_F_FOLF703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 12 ALA A 393
ASP A 180
PHE A 157
PHE A 155
ARG A 402
 None
 1.34A 4kyaF-6cboA:
undetectable		 4kyaF-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_H_FOLH703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 12 ALA A 393
ASP A 180
PHE A 157
PHE A 155
ARG A 402
 None
 1.33A 4kyaH-6cboA:
undetectable		 4kyaH-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 4qvlV-6cboA:
undetectable
4qvlb-6cboA:
undetectable		 4qvlV-6cboA:
13.14
4qvlb-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 ALA A  70
THR A 265
ALA A 268
GLY A  78
SER A  82
 None
 1.01A 4qvlK-6cboA:
undetectable
4qvlL-6cboA:
undetectable		 4qvlK-6cboA:
25.93
4qvlL-6cboA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 4qvlH-6cboA:
undetectable
4qvlN-6cboA:
undetectable		 4qvlH-6cboA:
13.14
4qvlN-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 ALA A  70
THR A 265
ALA A 268
GLY A  78
SER A  82
 None
 1.00A 4qvlY-6cboA:
undetectable
4qvlZ-6cboA:
undetectable		 4qvlY-6cboA:
25.93
4qvlZ-6cboA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 4qvmV-6cboA:
undetectable
4qvmb-6cboA:
undetectable		 4qvmV-6cboA:
13.14
4qvmb-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 4qvmH-6cboA:
undetectable
4qvmN-6cboA:
undetectable		 4qvmH-6cboA:
13.14
4qvmN-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 10 ALA A  70
THR A 265
ALA A 268
GLY A  78
SER A  82
 None
 1.01A 4qvmY-6cboA:
undetectable
4qvmZ-6cboA:
undetectable		 4qvmY-6cboA:
18.99
4qvmZ-6cboA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.45A 4qvpV-6cboA:
undetectable
4qvpb-6cboA:
undetectable		 4qvpV-6cboA:
13.14
4qvpb-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.45A 4qvpH-6cboA:
undetectable
4qvpN-6cboA:
undetectable		 4qvpH-6cboA:
13.14
4qvpN-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 4qvqV-6cboA:
undetectable
4qvqb-6cboA:
undetectable		 4qvqV-6cboA:
13.14
4qvqb-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 4qvqH-6cboA:
undetectable
4qvqN-6cboA:
undetectable		 4qvqH-6cboA:
13.14
4qvqN-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 10 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 4qvvV-6cboA:
0.1
4qvvb-6cboA:
undetectable		 4qvvV-6cboA:
13.14
4qvvb-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 10 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.43A 4qvvH-6cboA:
undetectable
4qvvN-6cboA:
undetectable		 4qvvH-6cboA:
13.14
4qvvN-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.45A 4qvwV-6cboA:
undetectable
4qvwb-6cboA:
undetectable		 4qvwV-6cboA:
13.14
4qvwb-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 ALA A  70
THR A 265
ALA A 268
GLY A  78
SER A  82
 None
 1.01A 4qvwK-6cboA:
undetectable
4qvwL-6cboA:
undetectable		 4qvwK-6cboA:
25.93
4qvwL-6cboA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.45A 4qvwH-6cboA:
undetectable
4qvwN-6cboA:
undetectable		 4qvwH-6cboA:
13.14
4qvwN-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 ALA A  70
THR A 265
ALA A 268
GLY A  78
SER A  82
 None
 1.01A 4qvwY-6cboA:
undetectable
4qvwZ-6cboA:
undetectable		 4qvwY-6cboA:
25.93
4qvwZ-6cboA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.47A 4qvyV-6cboA:
0.0
4qvyb-6cboA:
undetectable		 4qvyV-6cboA:
13.14
4qvyb-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.47A 4qvyH-6cboA:
undetectable
4qvyN-6cboA:
undetectable		 4qvyH-6cboA:
13.14
4qvyN-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.45A 4qw0V-6cboA:
undetectable
4qw0b-6cboA:
undetectable		 4qw0V-6cboA:
13.14
4qw0b-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.45A 4qw0H-6cboA:
undetectable
4qw0N-6cboA:
undetectable		 4qw0H-6cboA:
13.14
4qw0N-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 4qw1V-6cboA:
undetectable
4qw1b-6cboA:
undetectable		 4qw1V-6cboA:
13.14
4qw1b-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 ALA A  70
THR A 265
ALA A 268
GLY A  78
SER A  82
 None
 1.01A 4qw1K-6cboA:
undetectable
4qw1L-6cboA:
undetectable		 4qw1K-6cboA:
25.93
4qw1L-6cboA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 4qw1H-6cboA:
undetectable
4qw1N-6cboA:
undetectable		 4qw1H-6cboA:
13.14
4qw1N-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 4qw3V-6cboA:
undetectable
4qw3b-6cboA:
undetectable		 4qw3V-6cboA:
13.14
4qw3b-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 4qw3H-6cboA:
undetectable
4qw3N-6cboA:
undetectable		 4qw3H-6cboA:
13.14
4qw3N-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.43A 4qwuV-6cboA:
undetectable
4qwub-6cboA:
undetectable		 4qwuV-6cboA:
13.14
4qwub-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.43A 4qwuH-6cboA:
undetectable
4qwuN-6cboA:
undetectable		 4qwuH-6cboA:
13.14
4qwuN-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 10 GLY A 305
PHE A 301
ASP A 366
SER A 369
ALA A 370
 None
 1.19A 4wnuD-6cboA:
undetectable		 4wnuD-6cboA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.40A 5bxnV-6cboA:
undetectable
5bxnb-6cboA:
undetectable		 5bxnV-6cboA:
12.93
5bxnb-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 ALA A  70
THR A 265
ALA A 268
GLY A  78
SER A  82
 None
 0.99A 5bxnK-6cboA:
undetectable
5bxnL-6cboA:
undetectable		 5bxnK-6cboA:
25.93
5bxnL-6cboA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.41A 5bxnH-6cboA:
undetectable
5bxnN-6cboA:
undetectable		 5bxnH-6cboA:
12.93
5bxnN-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 ALA A  70
THR A 265
ALA A 268
GLY A  78
SER A  82
 None
 0.99A 5bxnY-6cboA:
undetectable
5bxnZ-6cboA:
undetectable		 5bxnY-6cboA:
25.93
5bxnZ-6cboA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 9 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.46A 5cz7V-6cboA:
undetectable
5cz7b-6cboA:
undetectable		 5cz7V-6cboA:
13.14
5cz7b-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.46A 5cz7H-6cboA:
undetectable
5cz7N-6cboA:
undetectable		 5cz7H-6cboA:
13.14
5cz7N-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.45A 5d0xV-6cboA:
undetectable
5d0xb-6cboA:
undetectable		 5d0xV-6cboA:
13.14
5d0xb-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 5d0xH-6cboA:
undetectable
5d0xN-6cboA:
undetectable		 5d0xH-6cboA:
13.14
5d0xN-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 12 ASP A 399
LEU A 184
SER A 130
ILE A 177
LEU A 223
 None
 1.12A 5hi6B-6cboA:
undetectable		 5hi6B-6cboA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 12 VAL A 256
ASP A 255
LEU A  89
LEU A 103
SER A 113
 None
 1.15A 5hnyB-6cboA:
undetectable		 5hnyB-6cboA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.46A 5l5fV-6cboA:
0.2
5l5fb-6cboA:
undetectable		 5l5fV-6cboA:
13.14
5l5fb-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.45A 5l5fH-6cboA:
undetectable
5l5fN-6cboA:
undetectable		 5l5fH-6cboA:
13.14
5l5fN-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 5l66V-6cboA:
undetectable
5l66b-6cboA:
undetectable		 5l66V-6cboA:
13.14
5l66b-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		5 / 11 SER A 238
THR A 271
THR A 272
ARG A 105
ALA A 266
 None
 1.44A 5l66H-6cboA:
undetectable
5l66N-6cboA:
undetectable		 5l66H-6cboA:
13.14
5l66N-6cboA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		4 / 6 ILE A  45
ILE A 308
HIS A 296
PHE A 376
 None
 0.90A 5vkqA-6cboA:
undetectable
5vkqB-6cboA:
undetectable		 5vkqA-6cboA:
undetectable
5vkqB-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		4 / 6 PHE A 376
ILE A  45
ILE A 308
HIS A 296
 None
 0.87A 5vkqA-6cboA:
undetectable
5vkqD-6cboA:
undetectable		 5vkqA-6cboA:
undetectable
5vkqD-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		3 / 3 SER A 219
HIS A 181
TYR A 189
 None
 0.89A 5y2tA-6cboA:
undetectable		 5y2tA-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 6cbo C-6'
AMINOTRANSFERASE
(Micromonospora
echinospora) 		4 / 5 SER A  53
VAL A  54
ASN A 236
PRO A 239
 None
 1.44A 6fi4A-6cboA:
undetectable
6fi4B-6cboA:
undetectable		 6fi4A-6cboA:
undetectable
6fi4B-6cboA:
undetectable