SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cbp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
MAN9-V3 GLYCOPEPTIDE
(Homo
sapiens;
Human
immunodeficiency
virus
1) 		5 / 11 GLY A 237
HIS A  35
SER A 173
GLY P 324
ASP A 107
 NAG  P 401 (-3.7A)
None
None
None
None
 1.11A 1jzsA-6cbpA:
undetectable		 1jzsA-6cbpA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
MAN9-V3 GLYCOPEPTIDE
(Homo
sapiens;
Human
immunodeficiency
virus
1) 		3 / 3 ASP A 107
ASN P 300
SER A 109
 None
 1.01A 3lsfB-6cbpA:
undetectable
3lsfE-6cbpA:
undetectable		 3lsfB-6cbpA:
undetectable
3lsfE-6cbpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
(Homo
sapiens) 		3 / 3 SER A 108
TYR A 106
PRO A 112
 None
NAG  A 302 ( 4.9A)
None
 0.95A 4k8cA-6cbpA:
undetectable		 4k8cA-6cbpA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
(Homo
sapiens) 		3 / 3 SER A 108
TYR A 106
PRO A 112
 None
NAG  A 302 ( 4.9A)
None
 0.91A 4kahA-6cbpA:
undetectable		 4kahA-6cbpA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
(Homo
sapiens) 		3 / 3 SER A 108
TYR A 106
PRO A 112
 None
NAG  A 302 ( 4.9A)
None
 0.92A 4kahB-6cbpA:
undetectable		 4kahB-6cbpA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
(Homo
sapiens) 		3 / 3 SER A 108
TYR A 106
PRO A 112
 None
NAG  A 302 ( 4.9A)
None
 0.94A 4kanA-6cbpA:
undetectable		 4kanA-6cbpA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
(Homo
sapiens) 		3 / 3 SER A 108
TYR A 106
PRO A 112
 None
NAG  A 302 ( 4.9A)
None
 0.96A 4kanB-6cbpA:
undetectable		 4kanB-6cbpA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
(Homo
sapiens) 		3 / 3 SER A 108
TYR A 106
PRO A 112
 None
NAG  A 302 ( 4.9A)
None
 0.93A 4kbeA-6cbpA:
undetectable		 4kbeA-6cbpA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
(Homo
sapiens) 		3 / 3 SER A 108
TYR A 106
PRO A 112
 None
NAG  A 302 ( 4.9A)
None
 0.94A 4kbeB-6cbpA:
undetectable		 4kbeB-6cbpA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
(Homo
sapiens) 		3 / 3 SER A 108
TYR A 106
PRO A 112
 None
NAG  A 302 ( 4.9A)
None
 0.94A 4lbgA-6cbpA:
undetectable		 4lbgA-6cbpA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
(Homo
sapiens) 		3 / 3 SER A 108
TYR A 106
PRO A 112
 None
NAG  A 302 ( 4.9A)
None
 0.92A 4lbgB-6cbpA:
undetectable		 4lbgB-6cbpA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ACL_A_SASA1111_1
(MCG)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
(Homo
sapiens) 		6 / 7 TYR A 111
SER A 178
TYR A 180
TYR A 193
GLU A 194
PRO A 199
 MAN  A 304 ( 4.5A)
None
None
MAN  A 305 ( 3.8A)
MAN  A 304 ( 2.7A)
MAN  A 306 ( 4.5A)
 1.10A 5aclA-6cbpA:
14.3		 5aclA-6cbpA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6cbp DH270.6 SINGLE CHAIN
VARIABLE FRAGMENT
MAN9-V3 GLYCOPEPTIDE
(Homo
sapiens;
Human
immunodeficiency
virus
1) 		4 / 5 TYR A  33
GLY P 324
TYR A 110
GLY A 236
 None
None
NAG  P 401 (-4.0A)
None
 1.05A 5ayfA-6cbpA:
undetectable		 5ayfA-6cbpA:
13.92