SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cc2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		4 / 6 GLN A 211
ARG A 184
PHE A 229
PHE A 355
 None
 1.42A 1e73M-6cc2A:
undetectable		 1e73M-6cc2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		3 / 3 TRP A 265
HIS A 359
MET A 260
 None
 1.20A 1l5qB-6cc2A:
undetectable		 1l5qB-6cc2A:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		3 / 3 ARG A 461
ILE A 283
TRP A 284
 None
 1.23A 1m8eB-6cc2A:
undetectable		 1m8eB-6cc2A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		4 / 8 ASP A 256
PHE A 343
TYR A 350
LEU A 244
 EDO  A 610 (-3.3A)
None
None
None
 0.92A 1rmtC-6cc2A:
undetectable		 1rmtC-6cc2A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		4 / 8 ASP A 256
PHE A 343
TYR A 350
LEU A 244
 EDO  A 610 (-3.3A)
None
None
None
 0.92A 1rmtD-6cc2A:
4.7		 1rmtD-6cc2A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		6 / 11 ALA A 357
ILE A 213
GLY A 362
ILE A 365
VAL A  37
ILE A 206
 None
 1.43A 2aquB-6cc2A:
undetectable		 2aquB-6cc2A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 10 LEU A 384
ALA A 357
ILE A 206
GLY A 362
CYH A 400
 None
 1.20A 2b17A-6cc2A:
undetectable		 2b17A-6cc2A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		4 / 8 SER A 516
ASP A 518
SER A 519
ASN A  59
 None
 1.14A 2cmlB-6cc2A:
undetectable		 2cmlB-6cc2A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		4 / 6 HIS A  78
PHE A 102
ARG A  16
GLY A  14
 None
 1.48A 2i30A-6cc2A:
undetectable		 2i30A-6cc2A:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 12 GLY A 396
ALA A 360
ILE A 206
VAL A  33
GLY A 381
 None
 0.86A 2rkgB-6cc2A:
undetectable		 2rkgB-6cc2A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		4 / 7 ILE A 469
GLY A 484
LEU A 494
PHE A 497
 None
 0.92A 2vctD-6cc2A:
undetectable		 2vctD-6cc2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 12 GLN A 307
LEU A 259
LEU A 281
PHE A 272
HIS A 273
 None
 1.20A 3adxA-6cc2A:
undetectable		 3adxA-6cc2A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 11 GLY A 396
ALA A 360
ILE A 206
VAL A  33
GLY A 381
 None
 0.97A 3ebzB-6cc2A:
undetectable		 3ebzB-6cc2A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 9 ILE A 213
GLY A 362
ILE A 364
VAL A  37
ILE A 206
 None
 1.25A 3ekyB-6cc2A:
undetectable		 3ekyB-6cc2A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 12 ASP A 356
LEU A 271
SER A 270
ILE A 277
LEU A 337
 None
 1.19A 3ko0G-6cc2A:
undetectable
3ko0H-6cc2A:
undetectable
3ko0I-6cc2A:
undetectable
3ko0J-6cc2A:
undetectable		 3ko0G-6cc2A:
16.67
3ko0H-6cc2A:
16.67
3ko0I-6cc2A:
16.67
3ko0J-6cc2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 12 LEU A 271
SER A 270
ILE A 277
LEU A 337
ASP A 356
 None
 1.22A 3ko0K-6cc2A:
undetectable
3ko0L-6cc2A:
undetectable
3ko0S-6cc2A:
undetectable
3ko0T-6cc2A:
undetectable		 3ko0K-6cc2A:
16.67
3ko0L-6cc2A:
16.67
3ko0S-6cc2A:
16.67
3ko0T-6cc2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 12 LEU A 271
SER A 270
ILE A 277
LEU A 337
ASP A 356
 None
 1.18A 3ko0M-6cc2A:
undetectable
3ko0N-6cc2A:
undetectable
3ko0O-6cc2A:
undetectable
3ko0P-6cc2A:
undetectable		 3ko0M-6cc2A:
16.67
3ko0N-6cc2A:
16.67
3ko0O-6cc2A:
16.67
3ko0P-6cc2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 10 ILE A 413
PHE A 468
ALA A 471
LEU A 470
ALA A 451
 PEG  A 616 (-4.9A)
None
None
None
None
 1.42A 3lw5B-6cc2A:
undetectable		 3lw5B-6cc2A:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		6 / 9 ALA A 357
ASP A 356
GLY A 362
ILE A 364
VAL A  37
ILE A 206
 None
 1.48A 3ndwB-6cc2A:
undetectable		 3ndwB-6cc2A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		6 / 9 ALA A 357
ILE A 213
GLY A 362
ILE A 364
VAL A  37
ILE A 206
 None
 1.37A 3ndwB-6cc2A:
undetectable		 3ndwB-6cc2A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		6 / 11 ALA A 357
ASP A 356
GLY A 362
ILE A 364
VAL A  37
ILE A 206
 None
 1.48A 3ndxB-6cc2A:
undetectable		 3ndxB-6cc2A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		6 / 11 ALA A 357
ILE A 213
GLY A 362
ILE A 364
VAL A  37
ILE A 206
 None
 1.37A 3ndxB-6cc2A:
undetectable		 3ndxB-6cc2A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		3 / 3 LYS A 463
ARG A 460
LYS A 291
 EDO  A 612 (-3.4A)
EDO  A 612 (-3.3A)
None
 1.07A 3okxA-6cc2A:
undetectable		 3okxA-6cc2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 11 ALA A 357
ILE A 213
GLY A 362
VAL A  37
ILE A 206
 None
 1.13A 3oxxB-6cc2A:
undetectable		 3oxxB-6cc2A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		3 / 3 TYR A 228
TYR A 201
GLU A 180
 None
 0.78A 3pfgA-6cc2A:
2.9		 3pfgA-6cc2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 10 GLY A 396
ALA A 360
ILE A 206
VAL A  33
GLY A 381
 None
 0.84A 3s43B-6cc2A:
undetectable		 3s43B-6cc2A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 12 GLY A 396
ALA A 360
ILE A 206
VAL A  33
GLY A 381
 None
 1.01A 3s56A-6cc2A:
undetectable		 3s56A-6cc2A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		5 / 12 GLY A 396
ALA A 360
ILE A 206
VAL A  33
GLY A 381
 None
 0.98A 3ucbB-6cc2A:
undetectable		 3ucbB-6cc2A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		4 / 6 ALA A 451
GLN A 452
LEU A 454
LEU A 407
 None
None
None
CL  A 614 ( 4.9A)
 1.17A 4xoyA-6cc2A:
undetectable		 4xoyA-6cc2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		4 / 6 ALA A 451
GLN A 452
LEU A 454
LEU A 407
 None
None
None
CL  A 614 ( 4.9A)
 1.27A 4xp3A-6cc2A:
undetectable		 4xp3A-6cc2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		4 / 6 LEU A  42
ILE A 189
ALA A 188
ALA A 204
 None
 0.63A 4zf8A-6cc2A:
undetectable		 4zf8A-6cc2A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		4 / 6 PHE A  46
LEU A  52
ARG A  16
GLY A  19
 None
 1.11A 5o4yA-6cc2A:
undetectable		 5o4yA-6cc2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE
(Entamoeba
histolytica) 		4 / 5 PHE A 112
THR A 118
ASP A  90
ASN A 495
 None
 1.26A 5ybbA-6cc2A:
undetectable		 5ybbA-6cc2A:
undetectable