SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ccb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		4 / 5 ASP C 113
LEU C 116
LYS C 117
MET C 434
 None
 1.42A 2gj5A-6ccbC:
undetectable		 2gj5A-6ccbC:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_B_CLUB809_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		4 / 6 TYR C 217
MET C 100
TYR C 486
HIS C 249
 None
 1.47A 2pncB-6ccbC:
undetectable		 2pncB-6ccbC:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		5 / 10 PHE C 317
ALA C 319
ALA C 174
LEU C 129
VAL C 181
 None
 1.35A 2wuzB-6ccbC:
undetectable		 2wuzB-6ccbC:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		3 / 3 SER C 481
ARG C 273
GLN C 287
 None
 1.02A 2xnrA-6ccbC:
undetectable		 2xnrA-6ccbC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_1
(NEURAMINIDASE A)		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		5 / 12 ARG C 298
ILE C 420
ASP C 180
TYR C 435
GLN C 203
 None
 1.46A 2ya7B-6ccbC:
undetectable		 2ya7B-6ccbC:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_1
(NEURAMINIDASE A)		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		5 / 12 ARG C 298
ILE C 420
ASP C 180
TYR C 435
GLN C 203
 None
 1.46A 2ya7D-6ccbC:
undetectable		 2ya7D-6ccbC:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 6ccb GLYCOPROTEIN 41
GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1;
Human
immunodeficiency
virus
1) 		5 / 12 ILE C 491
ASP A 632
ILE A 635
SER A 636
ALA C 497
 None
 1.15A 3axtA-6ccbC:
undetectable		 3axtA-6ccbC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 6ccb GLYCOPROTEIN 120
GLYCOPROTEIN 41
(Human
immunodeficiency
virus
1) 		4 / 4 THR C  37
VAL C  42
GLY A 531
THR A 529
 None
 1.04A 3cflA-6ccbC:
undetectable		 3cflA-6ccbC:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		4 / 8 VAL C 488
PRO C 220
GLN C 103
MET C 100
 None
 1.04A 4iilA-6ccbC:
undetectable		 4iilA-6ccbC:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		4 / 9 PHE C 376
HIS C 374
ILE C 424
MET C 426
 None
 1.28A 4jvlA-6ccbC:
undetectable		 4jvlA-6ccbC:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		3 / 3 LEU C 175
MET C 172
TYR C 191
 None
 0.92A 4p6xG-6ccbC:
undetectable		 4p6xG-6ccbC:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		5 / 12 GLY C 451
ILE C 284
SER C 274
ASN C 478
LEU C 452
 None
 1.32A 4pooA-6ccbC:
undetectable		 4pooA-6ccbC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 6ccb GLYCOPROTEIN 41
(Human
immunodeficiency
virus
1) 		3 / 3 THR A 612
ASN A 616
SER A 615
 None
 0.63A 4tvtA-6ccbA:
undetectable		 4tvtA-6ccbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_A_REAA602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 6ccb GLYCOPROTEIN 120
GLYCOPROTEIN 41
(Human
immunodeficiency
virus
1) 		5 / 12 GLY A 572
ARG A 567
THR A 569
PHE C  53
TRP A 571
 None
 1.46A 5fhzA-6ccbA:
undetectable		 5fhzA-6ccbA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		4 / 6 LEU C 342
LEU C 452
PHE C 361
LEU C 349
 None
 0.92A 5gs4A-6ccbC:
undetectable		 5gs4A-6ccbC:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		5 / 12 LEU C 416
THR C 387
GLN C 258
GLY C 451
LEU C 452
 None
 1.29A 5m50E-6ccbC:
undetectable		 5m50E-6ccbC:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 6ccb GLYCOPROTEIN 120
(Human
immunodeficiency
virus
1) 		5 / 12 GLY C 451
ILE C 449
THR C 256
VAL C 254
LEU C 390
 None
 1.48A 5nz0A-6ccbC:
undetectable		 5nz0A-6ccbC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 6ccb GLYCOPROTEIN 41
(Human
immunodeficiency
virus
1) 		4 / 7 GLY A 594
TRP A 596
ASP A 589
TYR A 586
 None
 1.21A 5vlmG-6ccbA:
undetectable		 5vlmG-6ccbA:
undetectable