SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ccu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 6ccu GLUCOSE-INDUCED
DEGRADATION PROTEIN
4 HOMOLOG
(Homo
sapiens) 		4 / 8 ASP A 196
LYS A 200
GLY A 203
PHE A 208
 None
 1.04A 2aouA-6ccuA:
undetectable		 2aouA-6ccuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 6ccu GLUCOSE-INDUCED
DEGRADATION PROTEIN
4 HOMOLOG
(Homo
sapiens) 		5 / 12 TYR A 272
GLY A 271
GLU A 270
ASP A 194
PHE A 257
 None
 1.27A 3qowA-6ccuA:
undetectable		 3qowA-6ccuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 6ccu GLUCOSE-INDUCED
DEGRADATION PROTEIN
4 HOMOLOG
(Homo
sapiens) 		4 / 7 PHE A 186
PHE A 205
ALA A 207
LEU A 225
 None
 1.04A 4ejgA-6ccuA:
undetectable		 4ejgA-6ccuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 6ccu GLUCOSE-INDUCED
DEGRADATION PROTEIN
4 HOMOLOG
(Homo
sapiens) 		4 / 6 PHE A 128
LEU A 284
ARG A 129
GLY A 130
 None
 1.05A 5o4yA-6ccuA:
undetectable		 5o4yA-6ccuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 6ccu GLUCOSE-INDUCED
DEGRADATION PROTEIN
4 HOMOLOG
(Homo
sapiens) 		4 / 6 LEU A 284
LYS A 236
GLU A 237
LEU A 159
 None
 1.33A 5xooA-6ccuA:
undetectable		 5xooA-6ccuA:
20.00