SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ccv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 6ccv -
(-) 		4 / 7 PHE F 273
PHE F 281
ALA F 188
ILE F 191
 None
 1.02A 1fxhA-6ccvF:
undetectable
1fxhB-6ccvF:
2.1		 1fxhA-6ccvF:
undetectable
1fxhB-6ccvF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 6ccv -
(-) 		3 / 3 ARG F 442
VAL F 413
THR F 448
 None
 0.60A 2nmzA-6ccvF:
undetectable		 2nmzA-6ccvF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 6ccv -
(-) 		3 / 3 ARG F 442
VAL F 413
THR F 448
 None
 0.81A 3k4vD-6ccvF:
undetectable		 3k4vD-6ccvF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 6ccv -
(-) 		3 / 3 ARG F 442
VAL F 413
THR F 448
 None
 0.71A 3ndtA-6ccvF:
undetectable		 3ndtA-6ccvF:
undetectable