SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cd8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YKI_A_NFZA1219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	6cd8	GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG (Homo sapiens)	4 / 8	TYR A 272 GLU A 270 GLY A 271 PHE A 205	None	1.09A	1ykiA-6cd8A: undetectable 1ykiB-6cd8A: undetectable	1ykiA-6cd8A: 12.22 1ykiB-6cd8A: 12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	6cd8	GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG (Homo sapiens)	5 / 10	ILE A 260 PHE A 128 LEU A 155 VAL A 148 LEU A 145	None None None UNX A 303 ( 4.6A) None	1.42A	2w98A-6cd8A: undetectable	2w98A-6cd8A: 13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5O4Y_A_CCSA14_0 (PHE-MAA-ASN-PRO-HIS- LEU-SER-TRP-SER-TRP- 9KK-9KK-ARG-CCS-GLY- NH2)	6cd8	GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG (Homo sapiens)	4 / 6	PHE A 128 LEU A 284 ARG A 129 GLY A 130	None	1.03A	5o4yA-6cd8A: undetectable	5o4yA-6cd8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XOO_A_ADNA506_1 (GLYCOSAMINOGLYCAN XYLOSYLKINASE)	6cd8	GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG (Homo sapiens)	4 / 6	LEU A 284 LYS A 236 GLU A 237 LEU A 159	None	1.31A	5xooA-6cd8A: undetectable	5xooA-6cd8A: 19.75

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YKI_A_NFZA1219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","6cd8","GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG","Homo sapiens",4,"TYR A 272;GLU A 270;GLY A 271;PHE A 205","None","1.09A","1ykiA-6cd8A:undetectable;1ykiB-6cd8A:undetectable","1ykiA-6cd8A:12.22;1ykiB-6cd8A:12.22"],["2W98_A_P1ZA1351_1","PROSTAGLANDIN REDUCTASE 2","6cd8","GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG","Homo sapiens",5,"ILE A 260;PHE A 128;LEU A 155;VAL A 148;LEU A 145","None;None;None;UNX A 303 ( 4.6A);None","1.42A","2w98A-6cd8A:undetectable","2w98A-6cd8A:13.12"],["5O4Y_A_CCSA14_0","PHE-MAA-ASN-PRO-HIS-LEU-SER-TRP-SER-TRP-9KK-9KK-ARG-CCS-GLY-NH2","6cd8","GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG","Homo sapiens",4,"PHE A 128;LEU A 284;ARG A 129;GLY A 130","None","1.03A","5o4yA-6cd8A:undetectable","5o4yA-6cd8A:undetectable"],["5XOO_A_ADNA506_1","GLYCOSAMINOGLYCAN XYLOSYLKINASE","6cd8","GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG","Homo sapiens",4,"LEU A 284;LYS A 236;GLU A 237;LEU A 159","None","1.31A","5xooA-6cd8A:undetectable","5xooA-6cd8A:19.75"]]