SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cdd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 4 LEU A 272
VAL A 406
CYH A 404
ALA A 418
 None
 1.26A 1mz9E-6cddA:
undetectable		 1mz9E-6cddA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P9G_A_ACTA42_0
(EAFP 2)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		3 / 3 CYH A 171
ARG A 154
CYH A 160
 ZN  A 701 (-2.3A)
None
ZN  A 701 (-2.3A)
 0.97A 1p9gA-6cddA:
undetectable		 1p9gA-6cddA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBK_A_RAPA225_1
(FKBP25)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		6 / 12 ASP A 314
LEU A 321
GLY A 343
VAL A 344
ILE A 345
ALA A 274
 None
 1.34A 1pbkA-6cddA:
undetectable		 1pbkA-6cddA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 7 GLY A 284
GLN A 312
ILE A 345
VAL A 344
 None
 0.99A 1rxcC-6cddA:
undetectable		 1rxcC-6cddA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 7 GLY A 284
GLN A 312
ILE A 345
VAL A 344
 None
 1.05A 1rxcL-6cddA:
undetectable		 1rxcL-6cddA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 7 LEU A 286
PHE A 262
ILE A 345
PHE A 271
 None
 0.78A 2opxA-6cddA:
undetectable		 2opxA-6cddA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 8 VAL A 330
TYR A 336
CYH A 566
CYH A 337
 None
 1.10A 2xz5A-6cddA:
undetectable
2xz5C-6cddA:
undetectable		 2xz5A-6cddA:
undetectable
2xz5C-6cddA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 8 VAL A 330
TYR A 336
CYH A 566
CYH A 337
 None
 1.09A 2xz5C-6cddA:
undetectable
2xz5D-6cddA:
undetectable		 2xz5C-6cddA:
undetectable
2xz5D-6cddA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 6 ARG A 276
ILE A 345
LEU A 286
GLU A 309
 None
 1.05A 2ya7A-6cddA:
undetectable		 2ya7A-6cddA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 6 ARG A 276
ILE A 345
LEU A 286
GLU A 309
 None
 1.05A 2ya7B-6cddA:
undetectable		 2ya7B-6cddA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 6 ARG A 276
ILE A 345
LEU A 286
GLU A 309
 None
 1.06A 2ya7D-6cddA:
undetectable		 2ya7D-6cddA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		3 / 3 TRP A 346
VAL A 429
ARG A 459
 None
 0.88A 3b0wA-6cddA:
undetectable		 3b0wA-6cddA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 6 GLY A 284
GLN A 312
ILE A 345
VAL A 344
 None
 1.08A 3kvvA-6cddA:
undetectable		 3kvvA-6cddA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 6 GLY A 284
GLN A 312
ILE A 345
VAL A 344
 None
 1.05A 3kvvB-6cddA:
undetectable		 3kvvB-6cddA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 6 GLY A 284
GLN A 312
ILE A 345
VAL A 344
 None
 1.09A 3kvvC-6cddA:
undetectable		 3kvvC-6cddA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 6 GLY A 284
GLN A 312
ILE A 345
VAL A 344
 None
 1.03A 3kvvD-6cddA:
undetectable		 3kvvD-6cddA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 6 GLY A 284
GLN A 312
ILE A 345
VAL A 344
 None
 1.02A 3kvvE-6cddA:
undetectable		 3kvvE-6cddA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 6 GLY A 284
GLN A 312
ILE A 345
VAL A 344
 None
 1.05A 3kvvF-6cddA:
undetectable		 3kvvF-6cddA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 8 GLN A 312
PRO A 310
GLN A 522
GLU A 520
 None
 1.04A 3oyaA-6cddA:
undetectable		 3oyaA-6cddA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 8 VAL A 330
TYR A 336
CYH A 566
CYH A 337
 None
 0.90A 4afgD-6cddA:
undetectable
4afgE-6cddA:
undetectable		 4afgD-6cddA:
16.59
4afgE-6cddA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 8 VAL A 330
TYR A 336
CYH A 566
CYH A 337
 None
 1.05A 4bqtC-6cddA:
undetectable
4bqtD-6cddA:
undetectable		 4bqtC-6cddA:
undetectable
4bqtD-6cddA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 8 GLY A 284
GLN A 312
ILE A 345
VAL A 344
 None
 0.99A 4e1vA-6cddA:
undetectable		 4e1vA-6cddA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 7 GLY A 284
GLN A 312
ILE A 345
VAL A 344
 None
 1.04A 4e1vB-6cddA:
undetectable		 4e1vB-6cddA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 6 GLY A 284
GLN A 312
ILE A 345
VAL A 344
 None
 1.01A 4e1vF-6cddA:
undetectable		 4e1vF-6cddA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 5 PRO A 219
ASP A 424
ASN A 423
VAL A 491
 None
 1.44A 4hytA-6cddA:
undetectable		 4hytA-6cddA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		5 / 12 GLU A 374
GLN A 281
SER A 407
LEU A 349
VAL A 360
 None
 1.40A 4k36A-6cddA:
undetectable		 4k36A-6cddA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 6 GLU A 516
GLU A 520
GLU A 513
GLU A 309
 None
 1.25A 4mi4A-6cddA:
undetectable		 4mi4A-6cddA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		4 / 7 GLU A 516
GLU A 520
GLU A 513
GLU A 309
 None
 1.27A 4mi4A-6cddA:
undetectable
4mi4C-6cddA:
undetectable		 4mi4A-6cddA:
19.75
4mi4C-6cddA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		3 / 3 GLU A 513
ILE A 267
ALA A 274
 None
 0.59A 4wnwB-6cddA:
undetectable		 4wnwB-6cddA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		5 / 11 ASP A 314
LEU A 321
VAL A 344
ILE A 345
ALA A 274
 None
 1.08A 5d75A-6cddA:
undetectable		 5d75A-6cddA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		5 / 11 ASP A 314
LEU A 321
VAL A 344
ILE A 345
ALA A 274
 None
 1.16A 5gpgA-6cddA:
undetectable		 5gpgA-6cddA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 6cdd NPL4 ZINC FINGER
(Chaetomium
thermophilum) 		3 / 3 GLU A 576
HIS A 572
VAL A 568
 None
 0.75A 5trqB-6cddA:
undetectable		 5trqB-6cddA:
undetectable