SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cdm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 6cdm VFP7.04 HEAVY CHAIN
(Mus
musculus) 		5 / 12 SER A  21
GLY A 104
THR A 105
THR A 107
VAL A 102
 None
 1.20A 2zifA-6cdmA:
undetectable		 2zifA-6cdmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6cdm VFP7.04 HEAVY CHAIN
(Mus
musculus) 		5 / 11 SER A 188
GLY A 134
THR A 135
ALA A 136
THR A 131
 None
 0.99A 5bxnH-6cdmA:
undetectable
5bxnI-6cdmA:
undetectable		 5bxnH-6cdmA:
18.78
5bxnI-6cdmA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 6cdm VFP7.04 HEAVY CHAIN
(Mus
musculus) 		5 / 11 SER A 188
GLY A 134
THR A 135
ALA A 136
THR A 131
 None
 1.10A 6hwdV-6cdmA:
undetectable		 6hwdV-6cdmA:
17.65