SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cdw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUV_A_VK3A4558_1 (PROTEIN YGIN)	6cdw	EFFECTOR PROTEIN LEM4 (LPG1101) (Legionella pneumophila)	4 / 7	TYR A 102 LEU A 107 TYR A 63 ILE A 30	None	1.20A	1tuvA-6cdwA: undetectable	1tuvA-6cdwA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QOW_A_SAMA417_0 (HISTONE-LYSINE N-METHYLTRANSFERASE)	6cdw	EFFECTOR PROTEIN LEM4 (LPG1101) (Legionella pneumophila)	5 / 12	GLY A 162 GLY A 168 VAL A 178 LYS A 136 ALA A 137	None	1.26A	3qowA-6cdwA: undetectable	3qowA-6cdwA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MGH_A_ACTA1320_0 (PHOSPHORIBOSYLFORMYL GLYCINAMIDINE SYNTHASE)	6cdw	EFFECTOR PROTEIN LEM4 (LPG1101) (Legionella pneumophila)	4 / 5	VAL A 178 LEU A 169 ILE A 154 LEU A 153	None	0.85A	4mghA-6cdwA: undetectable	4mghA-6cdwA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OU1_A_BEZA302_0 (RETRO-ALDOLASE, DESIGN RA114)	6cdw	EFFECTOR PROTEIN LEM4 (LPG1101) (Legionella pneumophila)	4 / 8	ILE A 92 LYS A 91 ILE A 117 ASN A 116	None	0.95A	4ou1A-6cdwA: undetectable	4ou1A-6cdwA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TUV_A_VK3A4558_1","PROTEIN YGIN","6cdw","EFFECTOR PROTEIN LEM4 (LPG1101)","Legionella pneumophila",4,"TYR A 102;LEU A 107;TYR A  63;ILE A  30","None","1.20A","1tuvA-6cdwA:undetectable","1tuvA-6cdwA:undetectable"],["3QOW_A_SAMA417_0","HISTONE-LYSINE N-METHYLTRANSFERASE","6cdw","EFFECTOR PROTEIN LEM4 (LPG1101)","Legionella pneumophila",5,"GLY A 162;GLY A 168;VAL A 178;LYS A 136;ALA A 137","None","1.26A","3qowA-6cdwA:undetectable","3qowA-6cdwA:undetectable"],["4MGH_A_ACTA1320_0","PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE","6cdw","EFFECTOR PROTEIN LEM4 (LPG1101)","Legionella pneumophila",4,"VAL A 178;LEU A 169;ILE A 154;LEU A 153","None","0.85A","4mghA-6cdwA:undetectable","4mghA-6cdwA:undetectable"],["4OU1_A_BEZA302_0","RETRO-ALDOLASE, DESIGN RA114","6cdw","EFFECTOR PROTEIN LEM4 (LPG1101)","Legionella pneumophila",4,"ILE A  92;LYS A  91;ILE A 117;ASN A 116","None","0.95A","4ou1A-6cdwA:undetectable","4ou1A-6cdwA:undetectable"]]