SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ce2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		4 / 7 GLY A  30
HIS A  48
TYR A  52
PRO A  68
 PE4  A 201 ( 3.6A)
None
None
None
 0.31A 1th6A-6ce2A:
21.1		 1th6A-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 6ce2 -
(-) 		7 / 12 LEU A   2
GLY A  23
GLY A  30
GLY A  33
ARG A  34
LYS A  49
TYR A  52
 PE4  A 201 ( 4.3A)
PE4  A 201 ( 3.9A)
PE4  A 201 ( 3.6A)
None
None
None
None
 1.14A 1y4lA-6ce2A:
23.8		 1y4lA-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 6ce2 -
(-) 		7 / 12 LEU A   2
GLY A  23
GLY A  30
GLY A  33
LYS A  49
TYR A  52
PRO A  68
 PE4  A 201 ( 4.3A)
PE4  A 201 ( 3.9A)
PE4  A 201 ( 3.6A)
None
None
None
None
 0.65A 1y4lA-6ce2A:
23.8		 1y4lA-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 6ce2 -
(-) 		7 / 12 LEU A   2
GLY A  23
GLY A  30
LEU A  32
GLY A  33
LYS A  49
TYR A  52
 PE4  A 201 ( 4.3A)
PE4  A 201 ( 3.9A)
PE4  A 201 ( 3.6A)
None
None
None
None
 1.12A 1y4lA-6ce2A:
23.8		 1y4lA-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 6ce2 -
(-) 		6 / 12 LEU A   5
GLY A  23
GLY A  30
LEU A  32
GLY A  33
LYS A  49
 PE4  A 201 ( 4.7A)
PE4  A 201 ( 3.9A)
PE4  A 201 ( 3.6A)
None
None
None
 1.38A 1y4lA-6ce2A:
23.8		 1y4lA-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 6ce2 -
(-) 		6 / 11 LEU A   2
LEU A   5
ARG A  34
HIS A  48
LYS A  49
TYR A  52
 PE4  A 201 ( 4.3A)
PE4  A 201 ( 4.7A)
None
None
None
None
 1.09A 1y4lB-6ce2A:
23.4		 1y4lB-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 6ce2 -
(-) 		7 / 11 LEU A   2
LEU A   5
VAL A  31
GLY A  33
HIS A  48
LYS A  49
TYR A  52
 PE4  A 201 ( 4.3A)
PE4  A 201 ( 4.7A)
None
None
None
None
None
 0.76A 1y4lB-6ce2A:
23.4		 1y4lB-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 6ce2 -
(-) 		5 / 11 LEU A   5
ARG A  34
HIS A  48
TYR A  52
LYS A  53
 PE4  A 201 ( 4.7A)
None
None
None
None
 1.19A 1y4lB-6ce2A:
23.4		 1y4lB-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 6ce2 -
(-) 		4 / 7 GLY A  30
HIS A  48
TYR A  52
PRO A  68
 PE4  A 201 ( 3.6A)
None
None
None
 0.34A 2armA-6ce2A:
21.1		 2armA-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 6ce2 -
(-) 		3 / 3 ASP A  76
TYR A  75
LYS A 100
 None
 1.01A 2othA-6ce2A:
21.3		 2othA-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		5 / 11 LEU A   5
GLY A   6
LYS A  16
PRO A  18
SER A  21
 PE4  A 201 ( 4.7A)
PE4  A 201 (-3.3A)
None
PE4  A 201 (-4.6A)
None
 0.70A 3bjwB-6ce2A:
20.6		 3bjwB-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		4 / 7 VAL A   3
GLN A  11
GLY A  15
ARG A 107
 None
 0.58A 3bjwB-6ce2A:
20.6		 3bjwB-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		5 / 10 VAL A   3
GLU A   4
GLY A   6
LYS A  69
ARG A  72
 None
None
PE4  A 201 (-3.3A)
None
None
 1.21A 3bjwD-6ce2A:
20.1		 3bjwD-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		5 / 10 VAL A   3
GLU A   4
GLY A   6
PRO A  18
ARG A  72
 None
None
PE4  A 201 (-3.3A)
PE4  A 201 (-4.6A)
None
 1.14A 3bjwD-6ce2A:
20.1		 3bjwD-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		4 / 7 VAL A   3
GLY A   6
PRO A  18
ARG A  72
 None
PE4  A 201 (-3.3A)
PE4  A 201 (-4.6A)
None
 0.76A 3bjwC-6ce2A:
20.0		 3bjwC-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		5 / 11 LEU A   5
GLY A   6
LYS A  16
PRO A  18
SER A  21
 PE4  A 201 ( 4.7A)
PE4  A 201 (-3.3A)
None
PE4  A 201 (-4.6A)
None
 0.64A 3bjwE-6ce2A:
20.7		 3bjwE-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		4 / 6 VAL A   3
GLN A  11
GLY A  15
ARG A 107
 None
 0.55A 3bjwE-6ce2A:
20.7		 3bjwE-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		5 / 12 LEU A   5
GLY A   6
LYS A  16
PRO A  18
SER A  21
 PE4  A 201 ( 4.7A)
PE4  A 201 (-3.3A)
None
PE4  A 201 (-4.6A)
None
 0.64A 3bjwF-6ce2A:
20.8		 3bjwF-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		4 / 7 VAL A   3
GLN A  11
GLY A  15
ARG A 107
 None
 0.55A 3bjwF-6ce2A:
20.8		 3bjwF-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		5 / 8 GLY A   6
LYS A   7
PRO A  18
LYS A  69
ARG A  72
 PE4  A 201 (-3.3A)
None
PE4  A 201 (-4.6A)
None
None
 1.12A 3bjwA-6ce2A:
20.2		 3bjwA-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		4 / 8 VAL A   3
GLY A   6
PRO A  18
ARG A  72
 None
PE4  A 201 (-3.3A)
PE4  A 201 (-4.6A)
None
 0.76A 3bjwA-6ce2A:
20.2		 3bjwA-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		5 / 11 LEU A   5
GLY A   6
LYS A  16
PRO A  18
SER A  21
 PE4  A 201 ( 4.7A)
PE4  A 201 (-3.3A)
None
PE4  A 201 (-4.6A)
None
 0.72A 3bjwH-6ce2A:
20.5		 3bjwH-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 6ce2 -
(-) 		4 / 7 VAL A   3
GLN A  11
GLY A  15
ARG A 107
 None
 0.66A 3bjwH-6ce2A:
20.5		 3bjwH-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 6ce2 -
(-) 		5 / 6 LYS A   7
LEU A  10
ASN A  17
PRO A  18
ARG A  72
 None
None
None
PE4  A 201 (-4.6A)
None
 0.34A 4yv5B-6ce2A:
24.3		 4yv5B-6ce2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 6ce2 -
(-) 		5 / 6 LYS A   7
LEU A  10
ASN A  17
PRO A  18
ARG A  72
 None
None
None
PE4  A 201 (-4.6A)
None
 0.37A 4yv5A-6ce2A:
24.4		 4yv5A-6ce2A:
undetectable