SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cen'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NW3_A_ACTA600_0 (HISTONE METHYLTRANSFERASE DOT1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	4 / 5	LEU A1245 VAL A1243 TYR A1174 THR A1232	None	1.39A	1nw3A-6cenA: undetectable	1nw3A-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2R3A_A_SAMA304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	9 / 12	ARG A1155 GLY A1156 TRP A1157 TYR A1200 HIS A1224 TYR A1261 CYH A1273 CYH A1275 LEU A1284	None SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A) SAM  A1301 (-4.6A)	0.62A	2r3aA-6cenA: 20.2	2r3aA-6cenA: 29.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OOI_A_SAMA237_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	10 / 12	ARG A1155 GLY A1156 TRP A1157 ASN A1198 TYR A1200 ASN A1223 HIS A1224 CYH A1273 CYH A1275 LEU A1284	None SAM  A1301 (-3.6A) None SAM  A1301 (-3.8A) SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A) SAM  A1301 (-4.6A)	0.67A	3ooiA-6cenA: 32.8	3ooiA-6cenA: 76.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OOI_A_SAMA237_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	10 / 12	ARG A1155 GLY A1156 TRP A1157 ASN A1198 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275	None SAM  A1301 (-3.6A) None SAM  A1301 (-3.8A) SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	0.34A	3ooiA-6cenA: 32.8	3ooiA-6cenA: 76.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OOI_A_SAMA237_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.14A	3ooiA-6cenA: 32.8	3ooiA-6cenA: 76.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OOI_A_SAMA237_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1275	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.12A	3ooiA-6cenA: 32.8	3ooiA-6cenA: 76.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OPE_A_SAMA7_0 (PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.42A	3opeA-6cenA: 25.8	3opeA-6cenA: 40.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OPE_A_SAMA7_0 (PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.45A	3opeA-6cenA: 25.8	3opeA-6cenA: 40.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OPE_A_SAMA7_0 (PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.41A	3opeA-6cenA: 25.8	3opeA-6cenA: 40.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OPE_B_SAMB8_0 (PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 9	GLY A1156 TRP A1157 TYR A1200 ASN A1223 TYR A1261	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) SAM  A1301 (-4.9A)	0.48A	3opeB-6cenA: 23.9	3opeB-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QXY_A_SAMA6734_0 (N-LYSINE METHYLTRANSFERASE SETD6)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TYR A1200 ASN A1223 HIS A1224 TYR A1261	SAM  A1301 (-3.6A) SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A)	0.90A	3qxyA-6cenA: 5.9	3qxyA-6cenA: 17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RC0_B_SAMB480_0 (N-LYSINE METHYLTRANSFERASE SETD6)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TYR A1200 ASN A1223 HIS A1224 TYR A1261	SAM  A1301 (-3.6A) SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A)	0.87A	3rc0B-6cenA: 5.6	3rc0B-6cenA: 17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQ4_A_SAMA500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275	SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	0.48A	3rq4A-6cenA: 6.4	3rq4A-6cenA: 25.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S8P_A_SAMA500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275	SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	0.52A	3s8pA-6cenA: 8.4	3s8pA-6cenA: 23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BUP_A_SAMA500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275	SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	0.54A	4bupA-6cenA: 8.6	4bupA-6cenA: 24.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YNM_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.36A	4ynmA-6cenA: 26.7	4ynmA-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YNM_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.35A	4ynmA-6cenA: 26.7	4ynmA-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YNM_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.38A	4ynmB-6cenA: 24.5	4ynmB-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YNM_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.31A	4ynmB-6cenA: 24.5	4ynmB-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YNM_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1275	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.11A	4ynmB-6cenA: 24.5	4ynmB-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YNP_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 HIS A1224 TYR A1261 CYH A1273 CYH A1275	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	0.38A	4ynpA-6cenA: 26.1	4ynpA-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YNP_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 TYR A1200 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.48A	4ynpA-6cenA: 26.1	4ynpA-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YNP_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273 CYH A1275	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	1.37A	4ynpA-6cenA: 26.1	4ynpA-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YNP_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1275	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.05A	4ynpA-6cenA: 26.1	4ynpA-6cenA: 41.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YNP_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 10	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.53A	4ynpB-6cenA: 24.1	4ynpB-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YNP_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 10	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.49A	4ynpB-6cenA: 24.1	4ynpB-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YNP_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 10	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.34A	4ynpB-6cenA: 24.1	4ynpB-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YNP_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 10	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1275	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.15A	4ynpB-6cenA: 24.1	4ynpB-6cenA: undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPA_A_SAMA3004_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.24A	4ypaA-6cenA: 26.8	4ypaA-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPA_A_SAMA3004_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 TYR A1200 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.46A	4ypaA-6cenA: 26.8	4ypaA-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPA_A_SAMA3004_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.38A	4ypaA-6cenA: 26.8	4ypaA-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPA_A_SAMA3004_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1275	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.06A	4ypaA-6cenA: 26.8	4ypaA-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPA_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.44A	4ypaB-6cenA: 25.9	4ypaB-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPA_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.34A	4ypaB-6cenA: 25.9	4ypaB-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPA_C_SAMC2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.27A	4ypaC-6cenA: 26.4	4ypaC-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPA_C_SAMC2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.29A	4ypaC-6cenA: 26.4	4ypaC-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPA_D_SAMD2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.44A	4ypaD-6cenA: 25.6	4ypaD-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPA_D_SAMD2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 TYR A1200 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.49A	4ypaD-6cenA: 25.6	4ypaD-6cenA: 41.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPE_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.36A	4ypeA-6cenA: 26.1	4ypeA-6cenA: 41.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPE_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.39A	4ypeA-6cenA: 26.1	4ypeA-6cenA: 41.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPE_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.31A	4ypeA-6cenA: 26.1	4ypeA-6cenA: 41.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YPE_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 11	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.48A	4ypeB-6cenA: 24.8	4ypeB-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YPE_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 11	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.51A	4ypeB-6cenA: 24.8	4ypeB-6cenA: undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPU_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.37A	4ypuA-6cenA: 26.0	4ypuA-6cenA: 40.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPU_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.32A	4ypuA-6cenA: 26.0	4ypuA-6cenA: 40.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YPU_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1275	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.11A	4ypuA-6cenA: 26.0	4ypuA-6cenA: 40.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YPU_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 11	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A)	0.62A	4ypuB-6cenA: 23.9	4ypuB-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CPR_B_SAMB402_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	PHE A1221 HIS A1224 TYR A1261 CYH A1273 CYH A1275	None None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	1.42A	5cprB-6cenA: 7.3	5cprB-6cenA: 23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0Y_A_FOLA201_1 (CONSERVED HYPOTHETICAL MEMBRANE PROTEIN)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	3 / 3	ARG A1187 LYS A1215 GLU A1177	None	0.83A	5d0yA-6cenA: undetectable	5d0yA-6cenA: 19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5INZ_D_DVAD15_0 (THETA DEFENSIN-2, D-PEPTIDE THETA DEFENSIN-2, L-PEPTIDE)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	3 / 3	GLY A1276 CYH A1280 CYH A1226	None ZN  A1304 (-2.3A) ZN  A1304 (-2.3A)	0.93A	5inzB-6cenA: undetectable	5inzB-6cenA: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JHN_A_SAMA1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.39A	5jhnA-6cenA: 15.6	5jhnA-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JHN_A_SAMA1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.27A	5jhnA-6cenA: 15.6	5jhnA-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JHN_A_SAMA1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.32A	5jhnA-6cenA: 15.6	5jhnA-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JHN_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.43A	5jhnB-6cenA: 19.7	5jhnB-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JHN_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.28A	5jhnB-6cenA: 19.7	5jhnB-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JHN_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.27A	5jhnB-6cenA: 19.7	5jhnB-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JIN_A_SAMA1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.43A	5jinA-6cenA: 15.6	5jinA-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JIN_A_SAMA1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 TYR A1200 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.35A	5jinA-6cenA: 15.6	5jinA-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JIN_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.29A	5jinB-6cenA: 19.8	5jinB-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JIY_A_SAMA1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.39A	5jiyA-6cenA: 19.5	5jiyA-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JIY_A_SAMA1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.26A	5jiyA-6cenA: 19.5	5jiyA-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JIY_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.44A	5jiyB-6cenA: 19.7	5jiyB-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JIY_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.30A	5jiyB-6cenA: 19.7	5jiyB-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JJ0_A_SAMA1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.42A	5jj0A-6cenA: 15.6	5jj0A-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JJ0_A_SAMA1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 TYR A1200 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.32A	5jj0A-6cenA: 15.6	5jj0A-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JJ0_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.29A	5jj0B-6cenA: 19.7	5jj0B-6cenA: 29.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JJ0_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.46A	5jj0B-6cenA: 19.7	5jj0B-6cenA: 29.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5LSU_A_SAMA1304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	9 / 12	ARG A1155 GLY A1156 TRP A1157 TYR A1200 HIS A1224 THR A1271 CYH A1273 CYH A1275 LEU A1284	None SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) None None ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A) SAM  A1301 (-4.6A)	0.58A	5lsuA-6cenA: 32.5	5lsuA-6cenA: 77.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5LSU_B_SAMB1304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	9 / 12	ARG A1155 GLY A1156 TRP A1157 PHE A1199 TYR A1200 HIS A1224 THR A1271 CYH A1275 LEU A1284	None SAM  A1301 (-3.6A) None None SAM  A1301 (-3.9A) None None ZN  A1304 (-2.3A) SAM  A1301 (-4.6A)	0.78A	5lsuB-6cenA: 31.7	5lsuB-6cenA: 77.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5LSU_B_SAMB1304_1 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	3 / 3	ASN A1223 TYR A1261 CYH A1273	SAM  A1301 (-3.2A) SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.24A	5lsuB-6cenA: 31.7	5lsuB-6cenA: 77.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T0K_A_SAMA1304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.40A	5t0kA-6cenA: 19.7	5t0kA-6cenA: 28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T0K_A_SAMA1304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.26A	5t0kA-6cenA: 19.7	5t0kA-6cenA: 28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T0K_A_SAMA1304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.27A	5t0kA-6cenA: 19.7	5t0kA-6cenA: 28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T0K_B_SAMB1304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.24A	5t0kB-6cenA: 19.8	5t0kB-6cenA: 28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T0K_B_SAMB1304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.39A	5t0kB-6cenA: 19.8	5t0kB-6cenA: 28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T0M_A_SAMA1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.25A	5t0mA-6cenA: 19.9	5t0mA-6cenA: 28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T0M_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.38A	5t0mB-6cenA: 19.7	5t0mB-6cenA: 28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T0M_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.26A	5t0mB-6cenA: 19.7	5t0mB-6cenA: 28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T0M_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.33A	5t0mB-6cenA: 19.7	5t0mB-6cenA: 28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TEG_B_SAMB401_0 (HISTONE H4 MUTANT PEPTIDE WITH H4K20NORLEUCINE N-LYSINE METHYLTRANSFERASE KMT5A)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 10	GLY A1156 TYR A1200 ASN A1223 HIS A1224 TYR A1261	SAM  A1301 (-3.6A) SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A)	0.26A	5tegB-6cenA: 14.3 5tegE-6cenA: undetectable	5tegB-6cenA: undetectable 5tegE-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TQR_B_SAMB8009_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EZH2, POLYCOMB PROTEIN SUZ12)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 10	GLY A1156 TYR A1200 ASN A1223 HIS A1224 TYR A1261	SAM  A1301 (-3.6A) SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A)	0.40A	5tqrB-6cenA: 4.2	5tqrB-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTF_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 11	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.46A	5ttfA-6cenA: 19.4	5ttfA-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTF_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 11	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.39A	5ttfA-6cenA: 19.4	5ttfA-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTF_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.49A	5ttfB-6cenA: 19.5	5ttfB-6cenA: 28.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTF_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.43A	5ttfB-6cenA: 19.5	5ttfB-6cenA: 28.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTF_C_SAMC1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.71A	5ttfC-6cenA: 19.4	5ttfC-6cenA: 28.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTF_D_SAMD1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 11	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.61A	5ttfD-6cenA: 15.6	5ttfD-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTG_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.51A	5ttgA-6cenA: 16.1	5ttgA-6cenA: 26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTG_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.17A	5ttgA-6cenA: 16.1	5ttgA-6cenA: 26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTG_B_SAMB1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 11	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.55A	5ttgB-6cenA: 15.6	5ttgB-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTG_B_SAMB1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 11	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.16A	5ttgB-6cenA: 15.6	5ttgB-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUY_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.38A	5tuyA-6cenA: 19.4	5tuyA-6cenA: 29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUY_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.34A	5tuyB-6cenA: 15.4	5tuyB-6cenA: 29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUZ_A_SAMA3001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	0.55A	5tuzA-6cenA: 16.0	5tuzA-6cenA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUZ_B_SAMB3001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.50A	5tuzB-6cenA: 15.8	5tuzB-6cenA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UPD_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD3)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	11 / 11	ARG A1155 GLY A1156 TRP A1157 ASN A1198 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275 LEU A1284	None SAM  A1301 (-3.6A) None SAM  A1301 (-3.8A) SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A) SAM  A1301 (-4.6A)	0.42A	5updA-6cenA: 33.5	5updA-6cenA: undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5V21_A_SAMA1804_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	8 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273 LEU A1284	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) SAM  A1301 (-4.6A)	0.50A	5v21A-6cenA: 25.8	5v21A-6cenA: 36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5V21_A_SAMA1804_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273 LEU A1284	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) SAM  A1301 (-4.6A)	1.33A	5v21A-6cenA: 25.8	5v21A-6cenA: 36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5V21_A_SAMA1804_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1275	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.05A	5v21A-6cenA: 25.8	5v21A-6cenA: 36.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9I_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.47A	5v9iA-6cenA: 19.4	5v9iA-6cenA: 28.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9I_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.45A	5v9iA-6cenA: 19.4	5v9iA-6cenA: 28.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9I_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 11	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.47A	5v9iB-6cenA: 19.5	5v9iB-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9I_C_SAMC1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 11	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.61A	5v9iC-6cenA: 19.4	5v9iC-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9I_D_SAMD1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 TYR A1200 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.71A	5v9iD-6cenA: 19.5	5v9iD-6cenA: 28.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9J_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.48A	5v9jA-6cenA: 16.0	5v9jA-6cenA: 26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9J_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.48A	5v9jA-6cenA: 16.0	5v9jA-6cenA: 26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9J_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.20A	5v9jA-6cenA: 16.0	5v9jA-6cenA: 26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9J_B_SAMB1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.53A	5v9jB-6cenA: 19.8	5v9jB-6cenA: 26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9J_B_SAMB1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.15A	5v9jB-6cenA: 19.8	5v9jB-6cenA: 26.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSC_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.40A	5vscA-6cenA: 19.6	5vscA-6cenA: 29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSC_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.32A	5vscA-6cenA: 19.6	5vscA-6cenA: 29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSC_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.29A	5vscB-6cenA: 15.4	5vscB-6cenA: 29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSC_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.34A	5vscB-6cenA: 15.4	5vscB-6cenA: 29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSD_A_SAMA3001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.54A	5vsdA-6cenA: 16.1	5vsdA-6cenA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSD_A_SAMA3001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.50A	5vsdA-6cenA: 16.1	5vsdA-6cenA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSD_B_SAMB3001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.53A	5vsdB-6cenA: 19.7	5vsdB-6cenA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSD_B_SAMB3001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.19A	5vsdB-6cenA: 19.7	5vsdB-6cenA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSE_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.41A	5vseA-6cenA: 19.7	5vseA-6cenA: 29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSE_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.30A	5vseA-6cenA: 19.7	5vseA-6cenA: 29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSE_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.29A	5vseB-6cenA: 19.4	5vseB-6cenA: 29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSE_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.30A	5vseB-6cenA: 19.4	5vseB-6cenA: 29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSF_A_SAMA3001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.55A	5vsfA-6cenA: 16.0	5vsfA-6cenA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSF_B_SAMB3001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.49A	5vsfB-6cenA: 16.0	5vsfB-6cenA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSF_B_SAMB3001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	0.47A	5vsfB-6cenA: 16.0	5vsfB-6cenA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXD_A_SAMA501_0 (SMYD3 METHYLTRANSFERASE)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	ARG A1155 GLY A1156 ASN A1223 HIS A1224 TYR A1261	None SAM  A1301 (-3.6A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A)	0.86A	5xxdA-6cenA: 5.3	5xxdA-6cenA: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5K_A_SAMA805_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH6)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	9 / 12	ARG A1155 GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275 LEU A1284	None SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A) SAM  A1301 (-4.6A)	0.62A	6a5kA-6cenA: 15.0	6a5kA-6cenA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5K_A_SAMA805_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH6)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	ARG A1155 GLY A1158 HIS A1224 TYR A1261 CYH A1273 CYH A1275 LEU A1284	None None None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A) SAM  A1301 (-4.6A)	1.26A	6a5kA-6cenA: 15.0	6a5kA-6cenA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5K_A_SAMA805_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH6)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.48A	6a5kA-6cenA: 15.0	6a5kA-6cenA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5M_A_SAMA805_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH6)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	10 / 12	ARG A1155 GLY A1156 TRP A1157 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275 LEU A1284	None SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A) SAM  A1301 (-4.6A)	0.67A	6a5mA-6cenA: 17.1	6a5mA-6cenA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5M_A_SAMA805_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH6)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.18A	6a5mA-6cenA: 17.1	6a5mA-6cenA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5M_A_SAMA805_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH6)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1275	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.13A	6a5mA-6cenA: 17.1	6a5mA-6cenA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AGO_A_SAMA2301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 11	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1273 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	0.65A	6agoA-6cenA: 24.7	6agoA-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AGO_A_SAMA2301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 11	GLY A1156 TYR A1200 HIS A1224 TYR A1261 CYH A1273 CYH A1275	SAM  A1301 (-3.6A) SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	0.69A	6agoA-6cenA: 24.7	6agoA-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AGO_A_SAMA2301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 11	TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275	None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	0.87A	6agoA-6cenA: 24.7	6agoA-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AGO_A_SAMA2301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 11	TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275	SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	0.92A	6agoA-6cenA: 24.7	6agoA-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BP4_A_SAMA505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 ARG A1220 HIS A1224 TYR A1261 CYH A1273	SAM  A1301 (-3.6A) None None None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A)	1.48A	6bp4A-6cenA: 19.0	6bp4A-6cenA: 27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BP4_A_SAMA505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 ARG A1220 HIS A1224 TYR A1261 CYH A1275 LEU A1284	SAM  A1301 (-3.6A) None None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A) SAM  A1301 (-4.6A)	0.64A	6bp4A-6cenA: 19.0	6bp4A-6cenA: 27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BP4_B_SAMB505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	8 / 12	GLY A1156 TRP A1157 TYR A1200 HIS A1224 TYR A1261 CYH A1273 CYH A1275 LEU A1284	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A) SAM  A1301 (-4.6A)	0.37A	6bp4B-6cenA: 19.6	6bp4B-6cenA: 27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BP4_B_SAMB505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1156 TRP A1157 TYR A1200 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.46A	6bp4B-6cenA: 19.6	6bp4B-6cenA: 27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BP4_B_SAMB505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	6 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1273 CYH A1275	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	1.39A	6bp4B-6cenA: 19.6	6bp4B-6cenA: 27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BP4_B_SAMB505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1158 TYR A1200 HIS A1224 TYR A1261 CYH A1275	None SAM  A1301 (-3.9A) None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	0.94A	6bp4B-6cenA: 19.6	6bp4B-6cenA: 27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CEN_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD3)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	11 / 11	ARG A1155 GLY A1156 TRP A1157 ASN A1198 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275 LEU A1284	None SAM  A1301 (-3.6A) None SAM  A1301 (-3.8A) SAM  A1301 (-3.9A) SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A) SAM  A1301 (-4.6A)	0.03A	6cenA-6cenA: 38.5	6cenA-6cenA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CHG_C_SAMC1101_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	TRP A1157 TYR A1200 PHE A1221 ASN A1223 HIS A1224	None SAM  A1301 (-3.9A) None SAM  A1301 (-3.2A) None	0.44A	6chgC-6cenA: 10.3	6chgC-6cenA: 29.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6INE_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 CYH A1273	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None ZN  A1304 ( 2.3A)	1.23A	6ineA-6cenA: 24.8	6ineA-6cenA: 37.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6INE_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	7 / 12	GLY A1156 TRP A1157 ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275	SAM  A1301 (-3.6A) None SAM  A1301 (-3.2A) None SAM  A1301 (-4.9A) ZN  A1304 ( 2.3A) ZN  A1304 (-2.3A)	0.43A	6ineA-6cenA: 24.8	6ineA-6cenA: 37.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6INE_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	5 / 12	GLY A1156 TRP A1157 HIS A1224 TYR A1261 CYH A1275	SAM  A1301 (-3.6A) None None SAM  A1301 (-4.9A) ZN  A1304 (-2.3A)	1.42A	6ineA-6cenA: 24.8	6ineA-6cenA: 37.97