SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cey'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 7 TYR A 191
HIS A 195
THR A 227
TYR A 264
 None
 1.33A 1afsB-6ceyA:
undetectable		 1afsB-6ceyA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.44A 1d4fC-6ceyA:
undetectable		 1d4fC-6ceyA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCB_P_DHIP3_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-L-GLN-D-PHE
-L-HIS-D-PRO-OH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 5 TYR A 237
TYR A 244
GLU A 240
TYR A 274
 GNP  A 500 (-4.7A)
None
GNP  A 500 ( 4.4A)
GNP  A 500 (-4.7A)
 1.19A 1mcbA-6ceyA:
0.0
1mcbB-6ceyA:
0.0
1mcbP-6ceyA:
undetectable		 1mcbA-6ceyA:
undetectable
1mcbB-6ceyA:
undetectable
1mcbP-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 8 ILE A 450
TYR A 340
ILE A 351
GLU A 352
 None
 0.85A 1mrjA-6ceyA:
undetectable		 1mrjA-6ceyA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.43A 1v8bA-6ceyA:
undetectable		 1v8bA-6ceyA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.45A 1v8bB-6ceyA:
undetectable		 1v8bB-6ceyA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.42A 1v8bC-6ceyA:
undetectable		 1v8bC-6ceyA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.46A 1v8bD-6ceyA:
undetectable		 1v8bD-6ceyA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 5 TYR A 403
TYR A 440
ILE A 443
GLY A 366
 None
 1.06A 2du8G-6ceyA:
undetectable		 2du8G-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 6 ILE A 208
PRO A 258
LEU A 381
ILE A 392
 GNP  A 500 ( 4.6A)
None
None
GNP  A 500 (-3.9A)
 0.88A 2q83B-6ceyA:
15.6		 2q83B-6ceyA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_C_SRYC403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 ASN A 373
ASP A 374
SER A 376
ASN A 378
SER A 413
 None
GNP  A 500 (-4.6A)
None
None
None
 1.11A 3havC-6ceyA:
17.1		 3havC-6ceyA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		3 / 3 GLU A 411
GLY A 418
THR A 419
 None
 0.46A 3iazA-6ceyA:
undetectable		 3iazA-6ceyA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		3 / 3 ASN A 378
ASP A 374
ARG A 475
 None
GNP  A 500 (-4.6A)
None
 0.92A 3k13A-6ceyA:
undetectable		 3k13A-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 6 VAL A 363
VAL A 444
PHE A 354
GLU A 439
 None
 1.47A 3n61A-6ceyA:
undetectable
3n61B-6ceyA:
undetectable		 3n61A-6ceyA:
11.02
3n61B-6ceyA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 11 LEU A 272
SER A 263
ILE A 265
GLY A 236
ALA A 238
 None
 1.13A 3n8yA-6ceyA:
undetectable		 3n8yA-6ceyA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG8_A_TOYA305_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 12 ASP A 374
SER A 376
HIS A 379
ASP A 396
GLU A 411
GLU A 416
 GNP  A 500 (-4.6A)
None
MG  A 700 ( 3.2A)
MG  A 702 ( 4.8A)
None
None
 0.43A 3sg8A-6ceyA:
30.7		 3sg8A-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG8_A_TOYA305_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 12 ASP A 374
SER A 376
HIS A 379
GLU A 411
GLU A 415
GLU A 416
 GNP  A 500 (-4.6A)
None
MG  A 700 ( 3.2A)
None
None
None
 0.70A 3sg8A-6ceyA:
30.7		 3sg8A-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG8_B_TOYB305_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 12 ASP A 374
SER A 376
HIS A 379
ASP A 396
GLU A 411
GLU A 416
 GNP  A 500 (-4.6A)
None
MG  A 700 ( 3.2A)
MG  A 702 ( 4.8A)
None
None
 0.57A 3sg8B-6ceyA:
31.0		 3sg8B-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG8_B_TOYB305_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 12 ASP A 374
SER A 376
HIS A 379
ASP A 396
GLU A 411
GLU A 416
 GNP  A 500 (-4.6A)
None
MG  A 700 ( 3.2A)
MG  A 702 ( 4.8A)
None
None
 1.44A 3sg8B-6ceyA:
31.0		 3sg8B-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_A_KANA304_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 10 ASP A 374
SER A 376
HIS A 379
ASP A 396
GLU A 411
GLU A 416
 GNP  A 500 (-4.6A)
None
MG  A 700 ( 3.2A)
MG  A 702 ( 4.8A)
None
None
 0.43A 3sg9A-6ceyA:
30.7		 3sg9A-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_A_KANA304_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 10 ASP A 374
SER A 376
HIS A 379
ASP A 396
GLU A 411
GLU A 416
 GNP  A 500 (-4.6A)
None
MG  A 700 ( 3.2A)
MG  A 702 ( 4.8A)
None
None
 1.46A 3sg9A-6ceyA:
30.7		 3sg9A-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_A_KANA304_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 10 ASP A 374
SER A 376
HIS A 379
ASP A 396
GLU A 415
GLU A 416
 GNP  A 500 (-4.6A)
None
MG  A 700 ( 3.2A)
MG  A 702 ( 4.8A)
None
None
 0.91A 3sg9A-6ceyA:
30.7		 3sg9A-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 8 ASP A 374
SER A 376
HIS A 379
ASP A 396
GLU A 411
GLU A 445
 GNP  A 500 (-4.6A)
None
MG  A 700 ( 3.2A)
MG  A 702 ( 4.8A)
None
None
 0.83A 3sg9B-6ceyA:
30.8		 3sg9B-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 6 TYR A 244
HIS A 372
HIS A 379
TYR A 237
 None
None
MG  A 700 ( 3.2A)
GNP  A 500 (-4.7A)
 0.86A 4df2A-6ceyA:
undetectable		 4df2A-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFB_A_KANA401_1
(APH(2')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 9 ASP A 374
SER A 376
HIS A 379
ASP A 396
GLU A 416
 GNP  A 500 (-4.6A)
None
MG  A 700 ( 3.2A)
MG  A 702 ( 4.8A)
None
 0.44A 4dfbA-6ceyA:
30.6		 4dfbA-6ceyA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFB_B_KANB401_1
(APH(2')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 10 ASP A 374
SER A 376
HIS A 379
ASP A 396
GLU A 411
GLU A 416
GLU A 445
 GNP  A 500 (-4.6A)
None
MG  A 700 ( 3.2A)
MG  A 702 ( 4.8A)
None
None
None
 0.75A 4dfbB-6ceyA:
31.0		 4dfbB-6ceyA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFB_B_KANB401_1
(APH(2')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 SER A 376
GLU A 411
GLU A 415
GLU A 416
GLU A 445
 None
 1.06A 4dfbB-6ceyA:
31.0		 4dfbB-6ceyA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFU_A_KANA401_1
(APH(2')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 12 ASP A 374
SER A 376
HIS A 379
ASP A 396
GLU A 411
GLU A 416
 GNP  A 500 (-4.6A)
None
MG  A 700 ( 3.2A)
MG  A 702 ( 4.8A)
None
None
 0.53A 4dfuA-6ceyA:
31.3		 4dfuA-6ceyA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFU_A_KANA401_1
(APH(2')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 SER A 376
HIS A 379
GLU A 411
GLU A 415
GLU A 416
 None
MG  A 700 ( 3.2A)
None
None
None
 0.79A 4dfuA-6ceyA:
31.3		 4dfuA-6ceyA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFU_B_KANB402_1
(APH(2')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 12 ASP A 374
SER A 376
HIS A 379
ASP A 396
GLU A 411
GLU A 416
 GNP  A 500 (-4.6A)
None
MG  A 700 ( 3.2A)
MG  A 702 ( 4.8A)
None
None
 0.52A 4dfuB-6ceyA:
31.2		 4dfuB-6ceyA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 11 ALA A 216
LYS A 226
PRO A 258
HIS A 379
ASP A 393
 GNP  A 500 ( 3.9A)
GNP  A 500 (-2.7A)
None
MG  A 700 ( 3.2A)
MG  A 702 (-1.7A)
 1.04A 4dt8A-6ceyA:
30.7		 4dt8A-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 11 GLY A 209
ALA A 216
ILE A 224
LYS A 226
PRO A 258
ILE A 277
HIS A 379
ILE A 392
 GNP  A 500 ( 4.3A)
GNP  A 500 ( 3.9A)
GNP  A 500 (-3.7A)
GNP  A 500 (-2.7A)
None
GNP  A 500 (-3.8A)
MG  A 700 ( 3.2A)
GNP  A 500 (-3.9A)
 0.63A 4dt8A-6ceyA:
30.7		 4dt8A-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 11 GLY A 209
ALA A 216
ILE A 224
PRO A 258
ILE A 277
HIS A 379
LEU A 381
ILE A 392
 GNP  A 500 ( 4.3A)
GNP  A 500 ( 3.9A)
GNP  A 500 (-3.7A)
None
GNP  A 500 (-3.8A)
MG  A 700 ( 3.2A)
None
GNP  A 500 (-3.9A)
 0.69A 4dt8A-6ceyA:
30.7		 4dt8A-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 10 GLY A 209
ALA A 216
ILE A 224
LYS A 226
PRO A 258
ASP A 393
 GNP  A 500 ( 4.3A)
GNP  A 500 ( 3.9A)
GNP  A 500 (-3.7A)
GNP  A 500 (-2.7A)
None
MG  A 702 (-1.7A)
 0.89A 4dt8B-6ceyA:
30.6		 4dt8B-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 10 GLY A 209
ALA A 216
ILE A 224
LYS A 226
PRO A 258
ILE A 277
ILE A 392
 GNP  A 500 ( 4.3A)
GNP  A 500 ( 3.9A)
GNP  A 500 (-3.7A)
GNP  A 500 (-2.7A)
None
GNP  A 500 (-3.8A)
GNP  A 500 (-3.9A)
 0.61A 4dt8B-6ceyA:
30.6		 4dt8B-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 10 GLY A 209
ALA A 216
ILE A 224
PRO A 258
ILE A 277
LEU A 381
ILE A 392
 GNP  A 500 ( 4.3A)
GNP  A 500 ( 3.9A)
GNP  A 500 (-3.7A)
None
GNP  A 500 (-3.8A)
None
GNP  A 500 (-3.9A)
 0.66A 4dt8B-6ceyA:
30.6		 4dt8B-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 10 ALA A 216
ILE A 224
LYS A 226
PRO A 258
ILE A 277
HIS A 379
ILE A 392
 GNP  A 500 ( 3.9A)
GNP  A 500 (-3.7A)
GNP  A 500 (-2.7A)
None
GNP  A 500 (-3.8A)
MG  A 700 ( 3.2A)
GNP  A 500 (-3.9A)
 0.57A 4dtaA-6ceyA:
30.7		 4dtaA-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 10 ALA A 216
ILE A 224
PRO A 258
ILE A 277
HIS A 379
LEU A 381
ILE A 392
 GNP  A 500 ( 3.9A)
GNP  A 500 (-3.7A)
None
GNP  A 500 (-3.8A)
MG  A 700 ( 3.2A)
None
GNP  A 500 (-3.9A)
 0.62A 4dtaA-6ceyA:
30.7		 4dtaA-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 ALA A 216
LYS A 226
PRO A 258
HIS A 379
ASP A 393
 GNP  A 500 ( 3.9A)
GNP  A 500 (-2.7A)
None
MG  A 700 ( 3.2A)
MG  A 702 (-1.7A)
 1.00A 4dtaA-6ceyA:
30.7		 4dtaA-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 8 ILE A 224
PRO A 258
ILE A 277
LEU A 381
ILE A 392
 GNP  A 500 (-3.7A)
None
GNP  A 500 (-3.8A)
None
GNP  A 500 (-3.9A)
 0.57A 4dtaB-6ceyA:
30.8		 4dtaB-6ceyA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 7 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.13A 4feuB-6ceyA:
17.3		 4feuB-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 8 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.20A 4feuF-6ceyA:
17.8		 4feuF-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 7 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.17A 4fevB-6ceyA:
17.5		 4fevB-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 7 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.16A 4fevD-6ceyA:
18.6		 4fevD-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 7 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.17A 4fevF-6ceyA:
17.8		 4fevF-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 7 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.19A 4fewB-6ceyA:
17.8		 4fewB-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 8 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.15A 4fewD-6ceyA:
18.4		 4fewD-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 8 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.14A 4fewF-6ceyA:
18.1		 4fewF-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 7 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.17A 4fexB-6ceyA:
17.7		 4fexB-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 8 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.14A 4gkhB-6ceyA:
18.4		 4gkhB-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 8 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.16A 4gkhD-6ceyA:
18.2		 4gkhD-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 8 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.14A 4gkhF-6ceyA:
18.2		 4gkhF-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 7 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.15A 4gkhG-6ceyA:
17.8		 4gkhG-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 6 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.20A 4gkhJ-6ceyA:
18.1		 4gkhJ-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 8 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.13A 4gkiA-6ceyA:
18.3		 4gkiA-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 8 ASP A 396
ASP A 393
ASP A 213
GLU A 240
 MG  A 702 ( 4.8A)
MG  A 702 (-1.7A)
None
GNP  A 500 ( 4.4A)
 1.15A 4gkiC-6ceyA:
18.0		 4gkiC-6ceyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.47A 4lvcB-6ceyA:
undetectable		 4lvcB-6ceyA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.44A 4pfjA-6ceyA:
undetectable		 4pfjA-6ceyA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 7 ASN A 296
GLU A 293
GLU A 294
GLU A 292
 None
 1.23A 4r87I-6ceyA:
undetectable		 4r87I-6ceyA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		3 / 3 MET A 290
GLU A 294
LEU A 298
 None
 0.48A 4v2oB-6ceyA:
undetectable		 4v2oB-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.44A 5axaA-6ceyA:
undetectable		 5axaA-6ceyA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.46A 5axaC-6ceyA:
undetectable		 5axaC-6ceyA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.46A 5hm8A-6ceyA:
undetectable		 5hm8A-6ceyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.46A 5hm8B-6ceyA:
undetectable		 5hm8B-6ceyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.46A 5hm8C-6ceyA:
undetectable		 5hm8C-6ceyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.46A 5hm8D-6ceyA:
undetectable		 5hm8D-6ceyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.46A 5hm8E-6ceyA:
undetectable		 5hm8E-6ceyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.46A 5hm8F-6ceyA:
undetectable		 5hm8F-6ceyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.46A 5hm8G-6ceyA:
undetectable		 5hm8G-6ceyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.46A 5hm8H-6ceyA:
undetectable		 5hm8H-6ceyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 9 ILE A 417
TYR A 287
LEU A 282
ARG A 300
ILE A 302
 None
 1.18A 5ifuB-6ceyA:
undetectable		 5ifuB-6ceyA:
10.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		11 / 12 ASP A 374
SER A 376
ASN A 378
ASP A 396
TYR A 408
GLU A 411
SER A 413
GLU A 416
GLU A 445
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
None
MG  A 702 ( 4.8A)
None
None
None
None
None
None
None
 0.50A 5iqbA-6ceyA:
16.8		 5iqbA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 12 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
GLU A 445
GLU A 451
 None
 0.89A 5iqbA-6ceyA:
16.8		 5iqbA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQB_B_KANB600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		10 / 11 ASP A 374
SER A 376
ASN A 378
ASP A 396
TYR A 408
GLU A 411
GLU A 416
GLU A 445
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
None
MG  A 702 ( 4.8A)
None
None
None
None
None
None
 0.53A 5iqbB-6ceyA:
43.1		 5iqbB-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQB_B_KANB600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 11 TYR A 408
GLU A 411
GLU A 415
GLU A 416
GLU A 445
GLU A 451
 None
 0.95A 5iqbB-6ceyA:
43.1		 5iqbB-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQB_C_KANC600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		10 / 11 ASP A 374
SER A 376
ASN A 378
ASP A 396
TYR A 408
GLU A 411
GLU A 416
GLU A 445
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
None
MG  A 702 ( 4.8A)
None
None
None
None
None
None
 0.48A 5iqbC-6ceyA:
43.2		 5iqbC-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQB_C_KANC600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		9 / 11 SER A 376
ASN A 378
TYR A 408
GLU A 411
GLU A 415
GLU A 416
GLU A 445
TYR A 448
GLU A 451
 None
 0.75A 5iqbC-6ceyA:
43.2		 5iqbC-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQB_D_KAND600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		11 / 12 ASP A 374
SER A 376
ASN A 378
ASP A 396
TYR A 408
GLU A 411
SER A 413
GLU A 416
GLU A 445
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
None
MG  A 702 ( 4.8A)
None
None
None
None
None
None
None
 0.60A 5iqbD-6ceyA:
41.4		 5iqbD-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQB_D_KAND600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 12 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
GLU A 445
 None
 0.87A 5iqbD-6ceyA:
41.4		 5iqbD-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQC_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASP A 396
TYR A 408
GLU A 411
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
MG  A 702 ( 4.8A)
None
None
None
None
None
 0.44A 5iqcA-6ceyA:
43.2		 5iqcA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQC_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 TYR A 408
GLU A 411
GLU A 415
GLU A 416
TYR A 448
 None
 0.90A 5iqcA-6ceyA:
43.2		 5iqcA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQC_B_51GB600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASP A 396
TYR A 408
GLU A 411
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
MG  A 702 ( 4.8A)
None
None
None
None
None
 0.46A 5iqcB-6ceyA:
42.7		 5iqcB-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQC_B_51GB600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 10 TYR A 408
GLU A 411
GLU A 415
GLU A 416
TYR A 448
GLU A 451
 None
 0.93A 5iqcB-6ceyA:
42.7		 5iqcB-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQC_C_51GC600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASP A 396
TYR A 408
GLU A 411
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
MG  A 702 ( 4.8A)
None
None
None
None
None
 0.31A 5iqcC-6ceyA:
43.3		 5iqcC-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQC_C_51GC600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 ASP A 393
TYR A 408
GLU A 411
GLU A 415
GLU A 416
 MG  A 702 (-1.7A)
None
None
None
None
 1.34A 5iqcC-6ceyA:
43.3		 5iqcC-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQC_C_51GC600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 10 TYR A 408
GLU A 411
GLU A 415
GLU A 416
TYR A 448
GLU A 451
 None
 0.78A 5iqcC-6ceyA:
43.3		 5iqcC-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQC_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASP A 396
TYR A 408
GLU A 411
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
MG  A 702 ( 4.8A)
None
None
None
None
None
 0.54A 5iqcD-6ceyA:
41.6		 5iqcD-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQC_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 10 ASP A 374
SER A 376
TYR A 408
GLU A 411
GLU A 416
GLU A 445
 GNP  A 500 (-4.6A)
None
None
None
None
None
 0.77A 5iqcD-6ceyA:
41.6		 5iqcD-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQC_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 TYR A 408
GLU A 411
GLU A 415
GLU A 416
GLU A 445
 None
 1.06A 5iqcD-6ceyA:
41.6		 5iqcD-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQC_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 TYR A 408
GLU A 411
GLU A 415
GLU A 416
TYR A 448
 None
 0.98A 5iqcD-6ceyA:
41.6		 5iqcD-6ceyA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		9 / 11 ASP A 374
SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 416
VAL A 444
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
None
None
None
None
None
None
None
 0.31A 5iqdA-6ceyA:
16.7		 5iqdA-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 11 SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 416
VAL A 444
GLU A 445
 None
 0.78A 5iqdA-6ceyA:
16.7		 5iqdA-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 11 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
VAL A 444
GLU A 445
 None
 0.99A 5iqdA-6ceyA:
16.7		 5iqdA-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 11 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
VAL A 444
TYR A 448
 None
 0.83A 5iqdA-6ceyA:
16.7		 5iqdA-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_B_RIOB600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		9 / 11 ASP A 374
SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 416
VAL A 444
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
None
None
None
None
None
None
None
 0.39A 5iqdB-6ceyA:
42.7		 5iqdB-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_B_RIOB600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 11 SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 416
VAL A 444
GLU A 445
 None
 0.79A 5iqdB-6ceyA:
42.7		 5iqdB-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_B_RIOB600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 11 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
VAL A 444
GLU A 445
 None
 0.97A 5iqdB-6ceyA:
42.7		 5iqdB-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_B_RIOB600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 11 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
VAL A 444
TYR A 448
 None
 0.82A 5iqdB-6ceyA:
42.7		 5iqdB-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_C_RIOC600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		10 / 12 ASP A 374
SER A 376
ASN A 378
TYR A 408
GLU A 411
SER A 413
GLU A 416
VAL A 444
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
None
None
None
None
None
None
None
None
 0.29A 5iqdC-6ceyA:
18.1		 5iqdC-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_C_RIOC600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 12 GLU A 411
SER A 413
GLU A 415
GLU A 416
VAL A 444
GLU A 445
 None
 1.06A 5iqdC-6ceyA:
18.1		 5iqdC-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_C_RIOC600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 12 SER A 376
ASN A 378
GLU A 411
SER A 413
GLU A 416
VAL A 444
GLU A 445
 None
 0.85A 5iqdC-6ceyA:
18.1		 5iqdC-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_C_RIOC600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 12 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
VAL A 444
TYR A 448
GLU A 451
 None
 0.75A 5iqdC-6ceyA:
18.1		 5iqdC-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 11 ASP A 374
SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 416
VAL A 444
GLU A 445
 GNP  A 500 (-4.6A)
None
None
None
None
None
None
None
 0.69A 5iqdD-6ceyA:
42.8		 5iqdD-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		9 / 11 ASP A 374
SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 416
VAL A 444
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
None
None
None
None
None
None
None
 0.49A 5iqdD-6ceyA:
42.8		 5iqdD-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 11 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
VAL A 444
GLU A 445
 None
 0.96A 5iqdD-6ceyA:
42.8		 5iqdD-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 11 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
VAL A 444
TYR A 448
 None
 0.91A 5iqdD-6ceyA:
42.8		 5iqdD-6ceyA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		9 / 11 ASP A 374
SER A 376
ASP A 396
TYR A 408
GLU A 411
SER A 413
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
MG  A 702 ( 4.8A)
None
None
None
None
None
None
 0.27A 5iqeA-6ceyA:
44.0		 5iqeA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 11 ASP A 393
TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
 MG  A 702 (-1.7A)
None
None
None
None
None
 1.40A 5iqeA-6ceyA:
44.0		 5iqeA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 11 SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 416
GLU A 445
 None
 0.73A 5iqeA-6ceyA:
44.0		 5iqeA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 11 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
GLU A 445
 None
 0.95A 5iqeA-6ceyA:
44.0		 5iqeA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 11 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
TYR A 448
GLU A 451
 None
 0.73A 5iqeA-6ceyA:
44.0		 5iqeA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_B_NMYB600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASP A 396
TYR A 408
GLU A 411
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
MG  A 702 ( 4.8A)
None
None
None
None
None
 0.37A 5iqeB-6ceyA:
43.2		 5iqeB-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_B_NMYB600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 ASP A 393
TYR A 408
GLU A 411
GLU A 415
GLU A 416
 MG  A 702 (-1.7A)
None
None
None
None
 1.35A 5iqeB-6ceyA:
43.2		 5iqeB-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_B_NMYB600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 10 SER A 376
TYR A 408
GLU A 411
GLU A 415
GLU A 416
GLU A 445
 None
 0.91A 5iqeB-6ceyA:
43.2		 5iqeB-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_B_NMYB600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 10 SER A 376
TYR A 408
GLU A 411
GLU A 415
GLU A 416
TYR A 448
GLU A 451
 None
 0.81A 5iqeB-6ceyA:
43.2		 5iqeB-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		11 / 12 ASP A 374
SER A 376
ASN A 378
ASP A 396
TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
None
MG  A 702 ( 4.8A)
None
None
None
None
None
None
None
 0.46A 5iqeC-6ceyA:
34.3		 5iqeC-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 12 SER A 376
ASN A 378
GLU A 411
SER A 413
GLU A 415
GLU A 416
GLU A 445
 None
 0.80A 5iqeC-6ceyA:
34.3		 5iqeC-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		9 / 12 ASP A 374
SER A 376
ASN A 378
ASP A 396
TYR A 408
GLU A 411
SER A 413
GLU A 416
GLU A 445
 GNP  A 500 (-4.6A)
None
None
MG  A 702 ( 4.8A)
None
None
None
None
None
 0.54A 5iqeD-6ceyA:
41.9		 5iqeD-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		10 / 12 ASP A 374
SER A 376
ASN A 378
ASP A 396
TYR A 408
GLU A 411
SER A 413
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
None
MG  A 702 ( 4.8A)
None
None
None
None
None
None
 0.60A 5iqeD-6ceyA:
41.9		 5iqeD-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 12 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
GLU A 445
 None
 0.95A 5iqeD-6ceyA:
41.9		 5iqeD-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 12 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
TYR A 448
 None
 1.07A 5iqeD-6ceyA:
41.9		 5iqeD-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASP A 396
TYR A 408
GLU A 411
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
MG  A 702 ( 4.8A)
None
None
None
None
None
 0.36A 5iqgA-6ceyA:
42.4		 5iqgA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 ASP A 393
TYR A 408
GLU A 411
GLU A 415
GLU A 416
 MG  A 702 (-1.7A)
None
None
None
None
 1.39A 5iqgA-6ceyA:
42.4		 5iqgA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 10 SER A 376
ASP A 396
TYR A 408
GLU A 411
GLU A 416
GLU A 445
 None
MG  A 702 ( 4.8A)
None
None
None
None
 0.77A 5iqgA-6ceyA:
42.4		 5iqgA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 TYR A 408
GLU A 411
GLU A 415
GLU A 416
GLU A 445
 None
 1.01A 5iqgA-6ceyA:
42.4		 5iqgA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 10 TYR A 408
GLU A 411
GLU A 415
GLU A 416
TYR A 448
GLU A 451
 None
 0.80A 5iqgA-6ceyA:
42.4		 5iqgA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_B_51GB600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASP A 396
TYR A 408
GLU A 411
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
MG  A 702 ( 4.8A)
None
None
None
None
None
 0.41A 5iqgB-6ceyA:
42.2		 5iqgB-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_B_51GB600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 ASP A 393
TYR A 408
GLU A 411
GLU A 415
GLU A 416
 MG  A 702 (-1.7A)
None
None
None
None
 1.37A 5iqgB-6ceyA:
42.2		 5iqgB-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_B_51GB600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 TYR A 408
GLU A 411
GLU A 415
GLU A 416
TYR A 448
 None
 0.88A 5iqgB-6ceyA:
42.2		 5iqgB-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_C_51GC600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 ASP A 374
SER A 376
ASP A 396
GLU A 411
GLU A 416
 GNP  A 500 (-4.6A)
None
MG  A 702 ( 4.8A)
None
None
 1.39A 5iqgC-6ceyA:
42.8		 5iqgC-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_C_51GC600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASP A 396
TYR A 408
GLU A 411
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
MG  A 702 ( 4.8A)
None
None
None
None
None
 0.33A 5iqgC-6ceyA:
42.8		 5iqgC-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_C_51GC600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 ASP A 393
TYR A 408
GLU A 411
GLU A 415
GLU A 416
 MG  A 702 (-1.7A)
None
None
None
None
 1.38A 5iqgC-6ceyA:
42.8		 5iqgC-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_C_51GC600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 10 TYR A 408
GLU A 411
GLU A 415
GLU A 416
TYR A 448
GLU A 451
 None
 0.75A 5iqgC-6ceyA:
42.8		 5iqgC-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASP A 396
TYR A 408
GLU A 411
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
MG  A 702 ( 4.8A)
None
None
None
None
None
 0.49A 5iqgD-6ceyA:
16.3		 5iqgD-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 ASP A 393
TYR A 408
GLU A 411
GLU A 415
GLU A 416
 MG  A 702 (-1.7A)
None
None
None
None
 1.38A 5iqgD-6ceyA:
16.3		 5iqgD-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 SER A 376
TYR A 408
GLU A 411
GLU A 416
GLU A 445
 None
 0.84A 5iqgD-6ceyA:
16.3		 5iqgD-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IQG_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 TYR A 408
GLU A 411
GLU A 415
GLU A 416
GLU A 445
 None
 1.03A 5iqgD-6ceyA:
16.3		 5iqgD-6ceyA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.44A 5m5kC-6ceyA:
undetectable		 5m5kC-6ceyA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.45A 5m66B-6ceyA:
undetectable		 5m66B-6ceyA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.45A 5utuH-6ceyA:
undetectable		 5utuH-6ceyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.44A 5v96B-6ceyA:
undetectable		 5v96B-6ceyA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.45A 5v96C-6ceyA:
undetectable		 5v96C-6ceyA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.45A 5v96D-6ceyA:
undetectable		 5v96D-6ceyA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 5 HIS A 372
SER A 397
GLY A 395
TYR A 244
 None
None
MG  A 702 ( 4.5A)
None
 1.21A 5yodB-6ceyA:
2.2		 5yodB-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_H_BEZH201_0
(NS3 PROTEASE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		4 / 5 HIS A 372
SER A 397
GLY A 395
TYR A 244
 None
None
MG  A 702 ( 4.5A)
None
 1.24A 5yodH-6ceyA:
2.2		 5yodH-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.45A 6aphA-6ceyA:
undetectable		 6aphA-6ceyA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASN A 378
TYR A 408
GLU A 411
SER A 413
GLU A 416
GLU A 445
 GNP  A 500 (-4.6A)
None
None
None
None
None
None
None
 0.65A 6c5uA-6ceyA:
43.5		 6c5uA-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASN A 378
TYR A 408
GLU A 411
SER A 413
GLU A 416
TYR A 448
 GNP  A 500 (-4.6A)
None
None
None
None
None
None
None
 0.26A 6c5uA-6ceyA:
43.5		 6c5uA-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 10 SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
GLU A 445
 None
 0.93A 6c5uA-6ceyA:
43.5		 6c5uA-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 10 SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
TYR A 448
 None
 0.77A 6c5uA-6ceyA:
43.5		 6c5uA-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_B_RIOB600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 9 ASP A 374
SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 416
GLU A 445
 GNP  A 500 (-4.6A)
None
None
None
None
None
None
 0.70A 6c5uB-6ceyA:
43.3		 6c5uB-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_B_RIOB600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 9 ASP A 374
SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 416
TYR A 448
 GNP  A 500 (-4.6A)
None
None
None
None
None
None
 0.28A 6c5uB-6ceyA:
43.3		 6c5uB-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_B_RIOB600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 9 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
GLU A 445
 None
 1.00A 6c5uB-6ceyA:
43.3		 6c5uB-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_B_RIOB600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		6 / 9 TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
TYR A 448
 None
 0.87A 6c5uB-6ceyA:
43.3		 6c5uB-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASN A 378
TYR A 408
GLU A 411
SER A 413
GLU A 416
GLU A 445
 GNP  A 500 (-4.6A)
None
None
None
None
None
None
None
 0.60A 6c5uD-6ceyA:
42.4		 6c5uD-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 10 ASP A 374
SER A 376
ASN A 378
TYR A 408
GLU A 411
SER A 413
GLU A 416
TYR A 448
 GNP  A 500 (-4.6A)
None
None
None
None
None
None
None
 0.47A 6c5uD-6ceyA:
42.4		 6c5uD-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 10 SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
GLU A 445
 None
 0.90A 6c5uD-6ceyA:
42.4		 6c5uD-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		7 / 10 SER A 376
TYR A 408
GLU A 411
SER A 413
GLU A 415
GLU A 416
TYR A 448
 None
 0.91A 6c5uD-6ceyA:
42.4		 6c5uD-6ceyA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CGD_A_AKNA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		9 / 10 GLY A 211
ASP A 374
ASP A 396
TYR A 408
GLU A 411
VAL A 444
GLU A 445
TYR A 448
GLU A 451
 GNP  A 500 ( 4.3A)
GNP  A 500 (-4.6A)
MG  A 702 ( 4.8A)
None
None
None
None
None
None
 0.28A 6cgdA-6ceyA:
43.8		 6cgdA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CGD_A_AKNA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 GLY A 211
ASP A 374
ASP A 396
TYR A 408
GLU A 416
 GNP  A 500 ( 4.3A)
GNP  A 500 (-4.6A)
MG  A 702 ( 4.8A)
None
None
 1.29A 6cgdA-6ceyA:
43.8		 6cgdA-6ceyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CGD_A_AKNA600_1
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 10 GLY A 211
ASP A 396
VAL A 444
TYR A 448
GLU A 451
 GNP  A 500 ( 4.3A)
MG  A 702 ( 4.8A)
None
None
None
 1.27A 6cgdA-6ceyA:
43.8		 6cgdA-6ceyA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_B_84GB600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		9 / 10 ASP A 374
SER A 376
ASN A 378
HIS A 379
TYR A 408
GLU A 411
GLU A 415
GLU A 416
GLU A 445
 GNP  A 500 (-4.6A)
None
None
MG  A 700 ( 3.2A)
None
None
None
None
None
 0.61A 6cggB-6ceyA:
43.0		 6cggB-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_B_84GB600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		9 / 10 ASP A 374
SER A 376
ASN A 378
HIS A 379
TYR A 408
GLU A 411
GLU A 415
GLU A 416
GLU A 451
 GNP  A 500 (-4.6A)
None
None
MG  A 700 ( 3.2A)
None
None
None
None
None
 0.30A 6cggB-6ceyA:
43.0		 6cggB-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_D_84GD600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		8 / 11 ASP A 374
SER A 376
ASN A 378
HIS A 379
TYR A 408
GLU A 411
GLU A 416
GLU A 445
 GNP  A 500 (-4.6A)
None
None
MG  A 700 ( 3.2A)
None
None
None
None
 0.54A 6cggD-6ceyA:
42.0		 6cggD-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_D_84GD600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		9 / 11 ASP A 374
SER A 376
ASN A 378
HIS A 379
TYR A 408
GLU A 411
GLU A 416
TYR A 448
GLU A 451
 GNP  A 500 (-4.6A)
None
None
MG  A 700 ( 3.2A)
None
None
None
None
None
 0.46A 6cggD-6ceyA:
42.0		 6cggD-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_D_84GD600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 11 TYR A 408
GLU A 411
GLU A 415
GLU A 416
GLU A 445
 None
 0.93A 6cggD-6ceyA:
42.0		 6cggD-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_D_84GD600_0
(BIFUNCTIONAL AAC/APH)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 11 TYR A 408
GLU A 411
GLU A 415
GLU A 416
TYR A 448
 None
 0.98A 6cggD-6ceyA:
42.0		 6cggD-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.47A 6gbnA-6ceyA:
undetectable		 6gbnA-6ceyA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.47A 6gbnB-6ceyA:
undetectable		 6gbnB-6ceyA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_1
(-)		 6cey BIFUNCTIONAL AAC/APH
(Staphylococcus
aureus) 		5 / 12 LEU A 247
ASP A 405
GLY A 311
HIS A 310
PHE A 305
 None
 1.49A 6gbnD-6ceyA:
undetectable		 6gbnD-6ceyA:
10.93