SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cf8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		4 / 7 TYR A 461
PHE A 458
GLY A 503
ILE A 282
 None
 0.80A 11gsB-6cf8A:
undetectable		 11gsB-6cf8A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		5 / 10 ALA A 403
LEU A 404
MET A 432
ILE A 417
HIS A 445
 None
 1.46A 1a52A-6cf8A:
undetectable		 1a52A-6cf8A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		5 / 10 ALA A 403
LEU A 404
MET A 432
ILE A 417
HIS A 445
 None
 1.44A 1a52B-6cf8A:
undetectable		 1a52B-6cf8A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		3 / 3 ALA A 221
VAL A 226
TRP A 260
 None
 1.02A 1gmkC-6cf8A:
undetectable
1gmkD-6cf8A:
undetectable		 1gmkC-6cf8A:
undetectable
1gmkD-6cf8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		5 / 12 ILE A 264
LEU A 236
ALA A 237
PHE A 241
LEU A 489
 None
 1.11A 1og5B-6cf8A:
undetectable		 1og5B-6cf8A:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		4 / 8 PHE A  60
SER A  31
LEU A  32
ILE A 394
 None
 0.80A 1sbrA-6cf8A:
0.9		 1sbrA-6cf8A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		5 / 12 LEU A 116
LEU A 135
THR A 136
LEU A 138
PHE A 142
 None
SO4  A 704 (-4.5A)
None
None
None
 0.77A 2bdmA-6cf8A:
undetectable		 2bdmA-6cf8A:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		4 / 8 PHE A 188
ALA A 192
LEU A 224
ASP A 171
 None
 1.02A 2bxkA-6cf8A:
undetectable		 2bxkA-6cf8A:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		4 / 6 PRO A 367
MET A 366
ASP A 374
TYR A 439
 None
 1.17A 2lh8A-6cf8A:
undetectable		 2lh8A-6cf8A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		4 / 6 GLU A  28
TYR A  20
PHE A 316
PRO A 315
 None
 1.42A 2vmyA-6cf8A:
undetectable		 2vmyA-6cf8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		5 / 11 THR A 470
ILE A 467
GLY A 468
GLY A 465
HIS A 445
 None
 1.00A 2y7kA-6cf8A:
undetectable		 2y7kA-6cf8A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		5 / 12 THR A 470
ILE A 467
GLY A 468
GLY A 465
HIS A 445
 None
 1.07A 2y7kC-6cf8A:
undetectable		 2y7kC-6cf8A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		5 / 12 THR A 470
ILE A 467
GLY A 468
GLY A 465
HIS A 445
 None
 1.05A 2y7kD-6cf8A:
undetectable		 2y7kD-6cf8A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		5 / 10 THR A 470
ILE A 467
GLY A 468
GLY A 465
HIS A 445
 None
 0.97A 2y7pA-6cf8A:
undetectable		 2y7pA-6cf8A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		3 / 3 GLU A 419
PHE A 427
GLN A 429
 None
 0.99A 3r55A-6cf8A:
undetectable		 3r55A-6cf8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		5 / 12 TYR A 283
ILE A 531
ILE A 282
LEU A 457
LEU A 474
 None
 1.19A 3vw1B-6cf8A:
undetectable		 3vw1B-6cf8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		4 / 6 LYS A 181
LEU A 174
SER A 207
THR A 176
 None
 1.26A 4d7bB-6cf8A:
undetectable		 4d7bB-6cf8A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		4 / 7 ILE A 151
LEU A 178
ILE A 157
ASP A 156
 None
 0.84A 4rmjA-6cf8A:
undetectable		 4rmjA-6cf8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AY6_A_VORA501_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 6cf8 LYTIC
TRANSGLYCOSYLASE
(Campylobacter
jejuni) 		5 / 9 TYR A 369
PHE A 393
ALA A 387
ALA A 385
LEU A 516
 None
 1.42A 6ay6A-6cf8A:
undetectable		 6ay6A-6cf8A:
12.65