SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cfp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN
(Influenza
A
virus;
Saccharomyces
cerevisiae) 		5 / 12 LEU A 470
ASN A 471
LEU A 469
ALA A 472
LEU A 511
 None
None
DMS  A 802 (-4.0A)
None
None
 1.38A 2aa6A-6cfpA:
undetectable		 2aa6A-6cfpA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN
(Saccharomyces
cerevisiae;
Influenza
A
virus) 		4 / 7 LEU A 694
GLN A 654
LEU A 268
PHE A 707
 None
 1.04A 2eijC-6cfpA:
undetectable
2eijJ-6cfpA:
undetectable		 2eijC-6cfpA:
undetectable
2eijJ-6cfpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN
(Saccharomyces
cerevisiae;
Influenza
A
virus) 		4 / 6 LEU A 694
GLN A 654
LEU A 268
PHE A 707
 None
 0.94A 2einP-6cfpA:
undetectable
2einW-6cfpA:
undetectable		 2einP-6cfpA:
undetectable
2einW-6cfpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN
(Influenza
A
virus;
Saccharomyces
cerevisiae) 		4 / 5 LEU A 345
LEU A 342
LEU A 543
MET A 311
 EZS  A 801 (-3.6A)
EZS  A 801 (-4.2A)
None
None
 0.91A 2oaxF-6cfpA:
undetectable		 2oaxF-6cfpA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN
(Saccharomyces
cerevisiae;
Influenza
A
virus) 		5 / 9 LEU A 500
LEU A 342
VAL A 545
GLY A 546
MET A 548
 None
EZS  A 801 (-4.2A)
None
None
None
 1.33A 2po7B-6cfpA:
undetectable		 2po7B-6cfpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN
(Saccharomyces
cerevisiae;
Influenza
A
virus) 		4 / 6 LEU A 694
GLN A 654
LEU A 268
PHE A 707
 None
 1.02A 2zxwP-6cfpA:
undetectable
2zxwW-6cfpA:
undetectable		 2zxwP-6cfpA:
undetectable
2zxwW-6cfpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN
(Influenza
A
virus;
Saccharomyces
cerevisiae) 		5 / 12 ALA A 439
LEU A 641
ILE A 428
ILE A 459
LEU A 586
 None
 1.01A 3gcsA-6cfpA:
undetectable		 3gcsA-6cfpA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN
(Influenza
A
virus;
Saccharomyces
cerevisiae) 		4 / 7 THR A 639
LEU A 702
GLN A 654
LEU A 655
 None
 1.08A 4ib4A-6cfpA:
undetectable		 4ib4A-6cfpA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN
(Influenza
A
virus;
Saccharomyces
cerevisiae) 		5 / 12 LEU A 543
LEU A 482
LEU A 345
PHE A 525
LEU A 500
 None
None
EZS  A 801 (-3.6A)
None
None
 1.23A 5iepA-6cfpA:
undetectable		 5iepA-6cfpA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN
(Influenza
A
virus;
Saccharomyces
cerevisiae) 		4 / 8 TYR A 458
SER A 405
ASN A 409
SER A 526
 None
 1.04A 5l1fA-6cfpA:
undetectable
5l1fB-6cfpA:
undetectable		 5l1fA-6cfpA:
7.68
5l1fB-6cfpA:
7.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN
(Saccharomyces
cerevisiae;
Influenza
A
virus) 		5 / 12 SER A 291
THR A 498
ILE A 292
LEU A 283
LEU A 563
 None
 1.34A 6a93A-6cfpA:
undetectable		 6a93A-6cfpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 6cfp UBIQUITIN-LIKE
PROTEIN
SMT3,POLYMERASE
ACIDIC PROTEIN
(Saccharomyces
cerevisiae;
Influenza
A
virus) 		5 / 12 SER A 291
THR A 498
ILE A 292
PHE A 525
LEU A 563
 None
 1.42A 6a93A-6cfpA:
undetectable		 6a93A-6cfpA:
undetectable