SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cg0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 7 HIS A 942
HIS A 937
HIS A 744
THR A 732
 ZN  A1101 (-3.3A)
ZN  A1101 (-3.4A)
None
None
 0.79A 1am6A-6cg0A:
undetectable		 1am6A-6cg0A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS A 942
HIS A 937
HIS A 744
THR A 732
 ZN  A1101 (-3.3A)
ZN  A1101 (-3.4A)
None
None
 0.80A 1azmA-6cg0A:
undetectable		 1azmA-6cg0A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS A 942
HIS A 937
HIS A 744
THR A 732
 ZN  A1101 (-3.3A)
ZN  A1101 (-3.4A)
None
None
 0.83A 1bzmA-6cg0A:
undetectable		 1bzmA-6cg0A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 12 SER D 104
LEU D  69
GLY D  96
PRO D  75
VAL D  45
 None
 1.10A 1fduC-6cg0D:
undetectable		 1fduC-6cg0D:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 7 TYR A 928
VAL A 815
GLU A 803
LEU A 882
 None
 0.98A 1j96B-6cg0A:
undetectable		 1j96B-6cg0A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 11 TYR A 928
VAL A 815
GLU A 803
LEU A 882
LEU A 879
 None
 1.24A 1mrqA-6cg0A:
undetectable		 1mrqA-6cg0A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		3 / 3 LEU A 993
HIS A 990
LYS A 989
 None
 1.02A 1y7iA-6cg0A:
undetectable		 1y7iA-6cg0A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 6 TYR A 725
ASP A 774
THR A 732
GLU A 736
 None
 1.45A 2dttB-6cg0A:
1.8
2dttC-6cg0A:
1.7		 2dttB-6cg0A:
18.49
2dttC-6cg0A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS A 942
HIS A 937
HIS A 744
THR A 732
 ZN  A1101 (-3.3A)
ZN  A1101 (-3.4A)
None
None
 0.74A 2gehA-6cg0A:
undetectable		 2gehA-6cg0A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS A 942
HIS A 937
HIS A 744
THR A 732
 ZN  A1101 (-3.3A)
ZN  A1101 (-3.4A)
None
None
 0.75A 2it4A-6cg0A:
undetectable		 2it4A-6cg0A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		4 / 6 LYS D 106
GLU D 126
TYR D 108
CYH D  67
 None
 1.46A 2x7hA-6cg0D:
undetectable		 2x7hA-6cg0D:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		3 / 3 ARG A 679
GLU A 597
SER A 539
 None
 0.92A 2xctD-6cg0A:
3.5		 2xctD-6cg0A:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 9 ASP D 132
HIS D 140
HIS D  94
ILE D 185
LEU D 184
 None
 1.28A 3hy7A-6cg0D:
undetectable		 3hy7A-6cg0D:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 10 LEU D 204
SER D 259
TYR D 277
GLY D 139
GLY D 158
 None
 1.21A 3ls4H-6cg0D:
undetectable		 3ls4H-6cg0D:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 5 PHE A 784
ILE A 785
GLY A 717
HIS A 665
 None
 1.08A 3r0lD-6cg0A:
undetectable		 3r0lD-6cg0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		3 / 3 GLN D   4
THR D   7
ASN D  53
 None
 0.87A 3v4tE-6cg0D:
undetectable		 3v4tE-6cg0D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 5 LEU A 538
ALA A 670
MET A 658
THR A 552
 None
 1.38A 3vasB-6cg0A:
undetectable		 3vasB-6cg0A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS A 942
HIS A 937
HIS A 744
THR A 732
 ZN  A1101 (-3.3A)
ZN  A1101 (-3.4A)
None
None
 0.81A 3w6hA-6cg0A:
undetectable		 3w6hA-6cg0A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 ARG A 679
GLU A 597
ARG A 556
VAL A 712
TYR A 707
 None
 1.46A 4ffwA-6cg0A:
undetectable		 4ffwA-6cg0A:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JI8_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		3 / 3 LYS A 653
LYS A 997
TRP A 992
 None
 1.40A 4ji8L-6cg0A:
undetectable		 4ji8L-6cg0A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 9 TYR A 928
VAL A 815
GLU A 803
LEU A 882
LEU A 879
 None
 1.23A 4l1xB-6cg0A:
undetectable		 4l1xB-6cg0A:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		3 / 3 PRO D  59
ASN D  11
HIS D  10
 None
 0.96A 4ma3H-6cg0D:
undetectable
4ma3L-6cg0D:
undetectable		 4ma3H-6cg0D:
undetectable
4ma3L-6cg0D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS A 942
HIS A 937
HIS A 744
THR A 732
 ZN  A1101 (-3.3A)
ZN  A1101 (-3.4A)
None
None
 0.74A 4n16A-6cg0A:
undetectable		 4n16A-6cg0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		4 / 7 THR D 125
ARG D 123
PHE D  62
SER D  63
 None
 0.91A 4o4dA-6cg0D:
undetectable		 4o4dA-6cg0D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA304_1
(CHITOSANASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 4 TYR A 707
ILE A 785
THR A 787
TYR A 559
 None
 1.49A 4oltA-6cg0A:
undetectable		 4oltA-6cg0A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB304_1
(CHITOSANASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 5 TYR A 707
ILE A 785
THR A 787
TYR A 559
 None
 1.50A 4oltB-6cg0A:
0.6		 4oltB-6cg0A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 9 PHE A 622
ALA A 554
LEU A 659
SER A 623
LEU A 655
 None
 1.27A 4or0A-6cg0A:
2.8		 4or0A-6cg0A:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 6 GLU A 786
THR A 787
THR A 669
HIS A 665
 None
 1.31A 4pfjB-6cg0A:
undetectable		 4pfjB-6cg0A:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		5 / 11 GLY D  96
GLY D  95
ILE D  93
GLY D  18
PHE D 206
 None
 1.05A 4qoiA-6cg0D:
undetectable
4qoiB-6cg0D:
undetectable		 4qoiA-6cg0D:
18.14
4qoiB-6cg0D:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 6 GLU A 597
TYR A 707
ILE A 785
THR A 787
 None
 1.29A 4qwpA-6cg0A:
undetectable		 4qwpA-6cg0A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 6 TYR A 707
ILE A 785
THR A 787
TYR A 559
 None
 1.49A 4qwpA-6cg0A:
undetectable		 4qwpA-6cg0A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB302_1
(CHITOSANASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 5 GLU A 597
TYR A 707
ILE A 785
THR A 787
 None
 1.31A 4qwpB-6cg0A:
undetectable		 4qwpB-6cg0A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB302_1
(CHITOSANASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 5 TYR A 707
ILE A 785
THR A 787
TYR A 559
 None
 1.46A 4qwpB-6cg0A:
undetectable		 4qwpB-6cg0A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		4 / 4 LEU D 289
ARG D 284
ILE D 273
ILE D 256
 None
 1.10A 5dzk2-6cg0D:
undetectable
5dzkM-6cg0D:
undetectable
5dzkN-6cg0D:
undetectable		 5dzk2-6cg0D:
undetectable
5dzkM-6cg0D:
undetectable
5dzkN-6cg0D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 2
(Mus
musculus) 		4 / 4 ILE D 273
ILE D 256
ARG D 284
LEU D 289
 None
 1.13A 5dzkh-6cg0D:
undetectable
5dzkn-6cg0D:
undetectable
5dzkv-6cg0D:
undetectable		 5dzkh-6cg0D:
undetectable
5dzkn-6cg0D:
undetectable
5dzkv-6cg0D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 7 GLY A 706
HIS A 795
ASP A 792
ASN A 961
 None
 1.02A 5nnwD-6cg0A:
undetectable		 5nnwD-6cg0A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 7 GLY A 706
HIS A 795
ASP A 792
ASN A 961
 None
 1.03A 5no9D-6cg0A:
undetectable		 5no9D-6cg0A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 6 HIS A 665
VAL A 715
LEU A 672
THR A 669
 None
 1.16A 5ogjA-6cg0A:
undetectable		 5ogjA-6cg0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 6 HIS A 665
VAL A 715
LEU A 672
THR A 669
 None
 1.15A 5ogjB-6cg0A:
undetectable		 5ogjB-6cg0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 5 HIS A 665
VAL A 715
LEU A 672
THR A 669
 None
 1.15A 5ohhA-6cg0A:
undetectable		 5ohhA-6cg0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 6 HIS A 665
VAL A 715
LEU A 672
THR A 669
 None
 1.17A 5ohhB-6cg0A:
undetectable		 5ohhB-6cg0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS A 942
HIS A 937
HIS A 744
THR A 732
 ZN  A1101 (-3.3A)
ZN  A1101 (-3.4A)
None
None
 0.75A 5tt3F-6cg0A:
undetectable		 5tt3F-6cg0A:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS A 942
HIS A 937
HIS A 744
THR A 732
 ZN  A1101 (-3.3A)
ZN  A1101 (-3.4A)
None
None
 0.89A 5tt3H-6cg0A:
undetectable		 5tt3H-6cg0A:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 10 LEU A 655
ALA A 562
PRO A 674
SER A 539
VAL A 532
 None
 1.32A 6b89A-6cg0A:
undetectable		 6b89A-6cg0A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 10 LEU A 655
ALA A 562
PRO A 674
SER A 539
VAL A 532
 None
 1.21A 6b89B-6cg0A:
1.6		 6b89B-6cg0A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 LEU A 657
SER A 561
VAL A 532
ILE A 535
ASP A 536
 None
 1.01A 6bxmA-6cg0A:
undetectable		 6bxmA-6cg0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 LEU A 657
SER A 561
VAL A 532
ILE A 535
ASP A 536
 None
 1.03A 6bxnA-6cg0A:
undetectable		 6bxnA-6cg0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 6 SER A 979
ASP A 986
GLN A 978
GLU A 985
 None
 1.43A 6djzA-6cg0A:
undetectable		 6djzA-6cg0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_C_GM4C301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 11 VAL A 620
ALA A 660
LEU A 711
GLU A 714
THR A 669
 None
 0.87A 6dk1C-6cg0A:
undetectable		 6dk1C-6cg0A:
undetectable