SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cg6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6cg6 CADHERIN-10
(Mus
musculus) 		4 / 7 GLY A 162
GLY A 190
GLN A 184
PHE A 106
 None
 0.97A 2qwxA-6cg6A:
undetectable
2qwxB-6cg6A:
undetectable		 2qwxA-6cg6A:
18.87
2qwxB-6cg6A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 6cg6 CADHERIN-10
(Mus
musculus) 		5 / 12 THR A 198
ILE A 148
GLN A 150
ASN A 202
ILE A 203
 None
 1.11A 3ddyA-6cg6A:
undetectable		 3ddyA-6cg6A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 6cg6 CADHERIN-10
(Mus
musculus) 		5 / 9 ILE A  96
PHE A   7
PHE A  92
PHE A  48
GLY A  43
 None
 1.36A 3ko0A-6cg6A:
undetectable
3ko0C-6cg6A:
undetectable		 3ko0A-6cg6A:
20.79
3ko0C-6cg6A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI201_1
(PROTEIN S100-A4)		 6cg6 CADHERIN-10
(Mus
musculus) 		5 / 9 PHE A  48
GLY A  43
ILE A  96
PHE A   7
PHE A  92
 None
 1.31A 3ko0H-6cg6A:
undetectable
3ko0I-6cg6A:
undetectable		 3ko0H-6cg6A:
20.79
3ko0I-6cg6A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 6cg6 CADHERIN-10
(Mus
musculus) 		5 / 10 PHE A  48
GLY A  43
ILE A  96
PHE A   7
PHE A  92
 None
 1.35A 3ko0L-6cg6A:
undetectable
3ko0N-6cg6A:
undetectable		 3ko0L-6cg6A:
20.79
3ko0N-6cg6A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 6cg6 CADHERIN-10
(Mus
musculus) 		5 / 10 ILE A  96
PHE A   7
PHE A  92
PHE A  48
GLY A  43
 None
 1.34A 3ko0R-6cg6A:
undetectable
3ko0T-6cg6A:
undetectable		 3ko0R-6cg6A:
20.79
3ko0T-6cg6A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 6cg6 CADHERIN-10
(Mus
musculus) 		5 / 11 ALA A  59
THR A  60
VAL A  21
ALA A  44
GLY A  43
 None
None
EDO  A 304 ( 4.2A)
None
None
 0.95A 3mg0K-6cg6A:
undetectable
3mg0L-6cg6A:
undetectable		 3mg0K-6cg6A:
18.23
3mg0L-6cg6A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 6cg6 CADHERIN-10
(Mus
musculus) 		4 / 6 GLU A 103
ASP A 134
ASP A  98
GLU A  11
 None
CA  A 303 ( 3.4A)
CA  A 301 (-3.0A)
CA  A 302 ( 3.0A)
 1.38A 4ntxA-6cg6A:
undetectable
4ntxC-6cg6A:
undetectable		 4ntxA-6cg6A:
10.89
4ntxC-6cg6A:
21.31