SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6cgm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 11 SER A 379
GLU A 384
TYR A 683
GLY A 651
LEU A 386
 None
 1.27A 1i9jH-6cgmA:
undetectable
1i9jL-6cgmA:
undetectable		 1i9jH-6cgmA:
14.29
1i9jL-6cgmA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 5 ASP A 315
SER A 204
ASN A 176
SER A 389
 None
 1.47A 1kiaB-6cgmA:
2.2		 1kiaB-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 6 ASP A 315
SER A 204
ASN A 176
SER A 389
 None
 1.47A 1kiaC-6cgmA:
undetectable		 1kiaC-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 5 GLY A 651
GLN A 650
VAL A 364
SER A 379
 None
 1.41A 1p6kB-6cgmA:
undetectable		 1p6kB-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 5 GLY A 651
GLN A 650
VAL A 364
SER A 379
 None
 1.43A 1rs6B-6cgmA:
1.4		 1rs6B-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 12 ALA A 448
LEU A 192
GLN A 387
ASN A 380
TYR A 394
 None
 1.21A 1u72A-6cgmA:
undetectable		 1u72A-6cgmA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 12 LEU A 656
VAL A 637
ILE A 641
MET A 466
SER A 413
 EDO  A 803 (-3.8A)
None
None
None
None
 1.14A 1zq9A-6cgmA:
2.6		 1zq9A-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 5 GLY A 651
GLN A 650
VAL A 364
SER A 379
 None
 1.22A 1zzqB-6cgmA:
undetectable		 1zzqB-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 5 GLY A 651
GLN A 650
VAL A 364
SER A 379
 None
 1.22A 1zzuA-6cgmA:
undetectable		 1zzuA-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 5 GLY A 651
GLN A 650
VAL A 364
SER A 379
 None
 1.42A 1zzuB-6cgmA:
1.4		 1zzuB-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 6 LEU A 201
LEU A 203
LEU A 278
LEU A 381
 None
 0.89A 2ab2A-6cgmA:
undetectable		 2ab2A-6cgmA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 6 ALA A 297
TYR A 323
TYR A 299
ILE A 337
 None
 1.27A 2dcfA-6cgmA:
undetectable		 2dcfA-6cgmA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 8 ALA A 504
TYR A 517
ILE A 500
TYR A 522
 None
 0.87A 2zm8A-6cgmA:
undetectable		 2zm8A-6cgmA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 8 ALA A 504
TYR A 517
ILE A 500
TYR A 522
 None
 0.89A 2zmaA-6cgmA:
undetectable		 2zmaA-6cgmA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 6 ILE A 552
MET A 420
LYS A 423
ILE A 425
 None
 0.94A 3eteA-6cgmA:
undetectable
3eteE-6cgmA:
undetectable		 3eteA-6cgmA:
10.06
3eteE-6cgmA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 7 MET A 420
LYS A 423
ILE A 425
ILE A 552
 None
 0.94A 3eteD-6cgmA:
undetectable
3eteF-6cgmA:
undetectable		 3eteD-6cgmA:
10.06
3eteF-6cgmA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 7 LEU A 143
GLN A 501
LEU A 414
LEU A 561
 None
 0.90A 3g8iA-6cgmA:
undetectable		 3g8iA-6cgmA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 7 ARG A 575
LEU A 414
ILE A 644
PHE A 492
 None
 1.04A 3ln1C-6cgmA:
undetectable		 3ln1C-6cgmA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 5 ARG A 575
LEU A 414
ILE A 644
PHE A 492
 None
 1.06A 3ln1D-6cgmA:
undetectable		 3ln1D-6cgmA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 6 THR A 681
GLN A 645
ILE A 652
SER A 379
 None
 1.15A 3peoG-6cgmA:
undetectable		 3peoG-6cgmA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		3 / 3 HIS A 313
SER A 374
ASN A 202
 None
 0.76A 3s8pB-6cgmA:
undetectable		 3s8pB-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 9 PHE A  81
LEU A  55
LEU A 127
ILE A  77
PHE A  68
 None
 1.11A 3tbgD-6cgmA:
undetectable		 3tbgD-6cgmA:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 5 THR A 591
ILE A 597
GLU A 602
PHE A 657
 None
 1.47A 4ac9C-6cgmA:
undetectable		 4ac9C-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 5 THR A 591
ILE A 597
GLU A 602
PHE A 657
 None
 1.48A 4acaC-6cgmA:
undetectable		 4acaC-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 4 TYR A 104
THR A 155
VAL A 125
ILE A 584
 None
 1.38A 4jx1F-6cgmA:
undetectable		 4jx1F-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8W_G_MTXG301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 9 PHE A 156
GLY A 462
GLY A 412
CYH A 577
LEU A 463
 None
 1.39A 4l8wG-6cgmA:
undetectable		 4l8wG-6cgmA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 11 ASN A 363
VAL A 364
ILE A 652
LEU A 656
SER A 383
 None
None
None
EDO  A 803 (-3.8A)
None
 1.41A 4m83A-6cgmA:
undetectable		 4m83A-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 8 GLU A 426
GLU A 505
GLN A 501
ILE A 500
 None
 0.83A 4mj8A-6cgmA:
undetectable		 4mj8A-6cgmA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 6 PHE A 360
ILE A 358
ARG A 350
VAL A 638
 None
None
EDO  A 803 (-4.1A)
None
 1.15A 4mk4B-6cgmA:
undetectable		 4mk4B-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 6 ILE A  77
ILE A 145
ILE A 124
LEU A  51
 None
 0.73A 4o8fB-6cgmA:
undetectable		 4o8fB-6cgmA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 6 LEU A 172
MET A 359
LEU A 386
MET A 458
 None
 1.11A 4okbA-6cgmA:
undetectable		 4okbA-6cgmA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		3 / 3 SER A 204
ASP A 315
GLN A 361
 None
 0.85A 4oltA-6cgmA:
undetectable
4oltB-6cgmA:
undetectable		 4oltA-6cgmA:
16.29
4oltB-6cgmA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		3 / 3 GLN A 361
SER A 204
ASP A 315
 None
 0.82A 4qwpA-6cgmA:
undetectable
4qwpB-6cgmA:
undetectable		 4qwpA-6cgmA:
17.98
4qwpB-6cgmA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 6 PHE A 171
LEU A 167
ASN A 158
PRO A 154
 None
 1.44A 4yv5B-6cgmA:
undetectable		 4yv5B-6cgmA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 6 PHE A 171
LEU A 167
ASN A 158
PRO A 154
 None
 1.39A 4yv5A-6cgmA:
undetectable		 4yv5A-6cgmA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		3 / 3 HIS A 313
SER A 374
ASN A 202
 None
 0.68A 5cprB-6cgmA:
undetectable		 5cprB-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 12 LEU A 173
LEU A 201
SER A 279
LEU A 278
LEU A 381
 None
 0.88A 5mwyA-6cgmA:
undetectable		 5mwyA-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 8 THR A 305
PRO A 303
VAL A 223
GLY A 222
 None
 0.90A 5nzyA-6cgmA:
undetectable		 5nzyA-6cgmA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 12 SER A 246
ALA A 249
TYR A 357
ALA A 248
GLY A 247
 None
 1.21A 5tzoA-6cgmA:
undetectable		 5tzoA-6cgmA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 12 SER A 246
ALA A 249
TYR A 357
ALA A 248
GLY A 247
 None
 1.22A 5tzoC-6cgmA:
undetectable		 5tzoC-6cgmA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 9 HIS A 647
LYS A 680
ILE A 679
ILE A 682
 None
 0.81A 5vkqB-6cgmA:
undetectable
5vkqC-6cgmA:
undetectable		 5vkqB-6cgmA:
undetectable
5vkqC-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 12 MET A 662
LEU A 667
ILE A 670
VAL A 637
PHE A 654
 None
EDO  A 803 ( 3.8A)
EDO  A 803 ( 4.3A)
None
None
 1.34A 5vlmB-6cgmA:
undetectable		 5vlmB-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 5 GLY A 651
GLN A 650
VAL A 364
SER A 379
 None
 1.40A 5vunA-6cgmA:
undetectable		 5vunA-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		3 / 3 SER A 374
HIS A 368
TYR A 574
 None
 0.99A 5y2tA-6cgmA:
undetectable		 5y2tA-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 12 SER A 460
SER A 152
THR A 153
ILE A 584
LEU A 172
 None
 1.27A 6a93A-6cgmA:
undetectable		 6a93A-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 12 LEU A 203
LEU A 251
GLY A 225
GLY A 222
GLY A 210
 None
 1.07A 6ce2B-6cgmA:
undetectable		 6ce2B-6cgmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 10 ILE A 578
ARG A 575
LEU A 463
LEU A 576
LEU A 414
 None
 0.98A 6f6nA-6cgmA:
undetectable
6f6nB-6cgmA:
undetectable		 6f6nA-6cgmA:
18.18
6f6nB-6cgmA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 10 ILE A 578
VAL A 429
LEU A 463
LEU A 576
LEU A 414
 None
 0.91A 6f6nA-6cgmA:
undetectable
6f6nB-6cgmA:
undetectable		 6f6nA-6cgmA:
18.18
6f6nB-6cgmA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 5 ARG A 453
ALA A 454
GLN A 516
ILE A 373
 None
 1.09A 6g9bA-6cgmA:
undetectable
6g9bB-6cgmA:
undetectable		 6g9bA-6cgmA:
18.18
6g9bB-6cgmA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		5 / 12 VAL A 283
ASP A 362
ASN A 320
ASN A 252
GLU A 294
 None
 1.37A 6gnfC-6cgmA:
undetectable		 6gnfC-6cgmA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 6 GLY A 651
LEU A 386
VAL A 638
PHE A 360
 None
 0.88A 6h7lA-6cgmA:
undetectable		 6h7lA-6cgmA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Bacillus
subtilis) 		4 / 6 GLY A 651
LEU A 386
VAL A 638
PHE A 360
 None
 0.88A 6h7lB-6cgmA:
undetectable		 6h7lB-6cgmA:
17.78